BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

251 related articles for article (PubMed ID: 29457782)

  • 1. Hypothalamic ER-associated degradation regulates POMC maturation, feeding, and age-associated obesity.
    Kim GH; Shi G; Somlo DR; Haataja L; Song S; Long Q; Nillni EA; Low MJ; Arvan P; Myers MG; Qi L
    J Clin Invest; 2018 Mar; 128(3):1125-1140. PubMed ID: 29457782
    [TBL] [Abstract][Full Text] [Related]  

  • 2. SEL1L-HRD1 ER-associated degradation regulates leptin receptor maturation and signaling in POMC neurons in diet-induced obesity.
    Mao H; Kim GH; Qi L
    Res Sq; 2024 Jan; ():. PubMed ID: 38260335
    [TBL] [Abstract][Full Text] [Related]  

  • 3. ER-associated degradation is required for vasopressin prohormone processing and systemic water homeostasis.
    Shi G; Somlo DRM; Kim GH; Prescianotto-Baschong C; Sun S; Beuret N; Long Q; Rutishauser J; Arvan P; Spiess M; Qi L
    J Clin Invest; 2017 Oct; 127(10):3897-3912. PubMed ID: 28920920
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Association of the SEL1L protein transmembrane domain with HRD1 ubiquitin ligase regulates ERAD-L.
    Hosokawa N; Wada I
    FEBS J; 2016 Jan; 283(1):157-72. PubMed ID: 26471130
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Hepatic Sel1L-Hrd1 ER-associated degradation (ERAD) manages FGF21 levels and systemic metabolism via CREBH.
    Bhattacharya A; Sun S; Wang H; Liu M; Long Q; Yin L; Kersten S; Zhang K; Qi L
    EMBO J; 2018 Nov; 37(22):. PubMed ID: 30389665
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Hepatic SEL1L-HRD1 ER-associated degradation regulates systemic iron homeostasis via ceruloplasmin.
    Thepsuwan P; Bhattacharya A; Song Z; Hippleheuser S; Feng S; Wei X; Das NK; Sierra M; Wei J; Fang D; Huang YM; Zhang K; Shah YM; Sun S
    Proc Natl Acad Sci U S A; 2023 Jan; 120(2):e2212644120. PubMed ID: 36595688
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Sel1L is indispensable for mammalian endoplasmic reticulum-associated degradation, endoplasmic reticulum homeostasis, and survival.
    Sun S; Shi G; Han X; Francisco AB; Ji Y; Mendonça N; Liu X; Locasale JW; Simpson KW; Duhamel GE; Kersten S; Yates JR; Long Q; Qi L
    Proc Natl Acad Sci U S A; 2014 Feb; 111(5):E582-91. PubMed ID: 24453213
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Endoplasmic reticulum-associated degradation is required for nephrin maturation and kidney glomerular filtration function.
    Yoshida S; Wei X; Zhang G; O'Connor CL; Torres M; Zhou Z; Lin L; Menon R; Xu X; Zheng W; Xiong Y; Otto E; Tang CA; Hua R; Verma R; Mori H; Zhang Y; Hu CA; Liu M; Garg P; Hodgin JB; Sun S; Bitzer M; Qi L
    J Clin Invest; 2021 Apr; 131(7):. PubMed ID: 33591954
    [TBL] [Abstract][Full Text] [Related]  

  • 9. SEL1L-HRD1 endoplasmic reticulum-associated degradation controls STING-mediated innate immunity by limiting the size of the activable STING pool.
    Ji Y; Luo Y; Wu Y; Sun Y; Zhao L; Xue Z; Sun M; Wei X; He Z; Wu SA; Lin LL; Lu Y; Chang L; Chen F; Chen S; Qian W; Xu X; Chen S; Pan D; Zhou Z; Xia S; Hu CA; Liang T; Qi L
    Nat Cell Biol; 2023 May; 25(5):726-739. PubMed ID: 37142791
    [TBL] [Abstract][Full Text] [Related]  

  • 10. SEL1L protein critically determines the stability of the HRD1-SEL1L endoplasmic reticulum-associated degradation (ERAD) complex to optimize the degradation kinetics of ERAD substrates.
    Iida Y; Fujimori T; Okawa K; Nagata K; Wada I; Hosokawa N
    J Biol Chem; 2011 May; 286(19):16929-39. PubMed ID: 21454652
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Marchf6 E3 ubiquitin ligase critically regulates endoplasmic reticulum stress, ferroptosis, and metabolic homeostasis in POMC neurons.
    Mun SH; Lee CS; Kim HJ; Kim J; Lee H; Yang J; Im SH; Kim JH; Seong JK; Hwang CS
    Cell Rep; 2023 Jul; 42(7):112746. PubMed ID: 37421621
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Abnormal expression of ER quality control and ER associated degradation proteins in the dorsolateral prefrontal cortex in schizophrenia.
    Kim P; Scott MR; Meador-Woodruff JH
    Schizophr Res; 2018 Jul; 197():484-491. PubMed ID: 29496332
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Mitofusin 2 in POMC neurons connects ER stress with leptin resistance and energy imbalance.
    Schneeberger M; Dietrich MO; Sebastián D; Imbernón M; Castaño C; Garcia A; Esteban Y; Gonzalez-Franquesa A; Rodríguez IC; Bortolozzi A; Garcia-Roves PM; Gomis R; Nogueiras R; Horvath TL; Zorzano A; Claret M
    Cell; 2013 Sep; 155(1):172-87. PubMed ID: 24074867
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Hypomorphic variants of SEL1L-HRD1 ER-associated degradation are associated with neurodevelopmental disorders.
    Wang HH; Lin LL; Li ZJ; Wei X; Askander O; Cappuccio G; Hashem MO; Hubert L; Munnich A; Alqahtani M; Pang Q; Burmeister M; Lu Y; Poirier K; Besmond C; Sun S; Brunetti-Pierri N; Alkuraya FS; Qi L
    J Clin Invest; 2024 Jan; 134(2):. PubMed ID: 37943610
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The Sel1L-Hrd1 Endoplasmic Reticulum-Associated Degradation Complex Manages a Key Checkpoint in B Cell Development.
    Ji Y; Kim H; Yang L; Sha H; Roman CA; Long Q; Qi L
    Cell Rep; 2016 Sep; 16(10):2630-2640. PubMed ID: 27568564
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Role of HERP and a HERP-related protein in HRD1-dependent protein degradation at the endoplasmic reticulum.
    Huang CH; Chu YR; Ye Y; Chen X
    J Biol Chem; 2014 Feb; 289(7):4444-54. PubMed ID: 24366871
    [TBL] [Abstract][Full Text] [Related]  

  • 17. How Is the Fidelity of Proteins Ensured in Terms of Both Quality and Quantity at the Endoplasmic Reticulum? Mechanistic Insights into E3 Ubiquitin Ligases.
    Kang JA; Jeon YJ
    Int J Mol Sci; 2021 Feb; 22(4):. PubMed ID: 33669844
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The Integrated UPR and ERAD in Oligodendrocytes Maintain Myelin Thickness in Adults by Regulating Myelin Protein Translation.
    Wu S; Stone S; Nave KA; Lin W
    J Neurosci; 2020 Oct; 40(43):8214-8232. PubMed ID: 32958569
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Deletion of liver kinase B1 in POMC neurons predisposes to diet-induced obesity.
    Wu Z; Han J; Xue J; Xi P; Wang H; He L; Wang Q; Liang H; Sun X; Tian D
    Life Sci; 2020 Oct; 258():118204. PubMed ID: 32763296
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Obesity induces hypothalamic endoplasmic reticulum stress and impairs proopiomelanocortin (POMC) post-translational processing.
    Cakir I; Cyr NE; Perello M; Litvinov BP; Romero A; Stuart RC; Nillni EA
    J Biol Chem; 2013 Jun; 288(24):17675-88. PubMed ID: 23640886
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.