137 related articles for article (PubMed ID: 29458050)
1. Investigation of metabolic stability of the novel ALK inhibitor brigatinib by liquid chromatography tandem mass spectrometry.
Darwish HW; Kadi AA; Attwa MW; Almutairi HS
Clin Chim Acta; 2018 May; 480():180-185. PubMed ID: 29458050
[TBL] [Abstract][Full Text] [Related]
2. Investigation of metabolic degradation of new ALK inhibitor: Entrectinib by LC-MS/MS.
Attwa MW; Darwish HW; Alhazmi HA; Kadi AA
Clin Chim Acta; 2018 Oct; 485():298-304. PubMed ID: 30006284
[TBL] [Abstract][Full Text] [Related]
3. Bioanalytical liquid chromatography-tandem mass spectrometric assay for the quantification of the ALK inhibitors alectinib, brigatinib and lorlatinib in plasma and mouse tissue homogenates.
Sparidans RW; Li W; Schinkel AH; Schellens JHM; Beijnen JH
J Pharm Biomed Anal; 2018 Nov; 161():136-143. PubMed ID: 30149189
[TBL] [Abstract][Full Text] [Related]
4. Liquid chromatography tandem mass spectrometry method for the quantification of vandetanib in human plasma and rat liver microsomes matrices: metabolic stability investigation.
Amer SM; Kadi AA; Darwish HW; Attwa MW
Chem Cent J; 2017 May; 11(1):45. PubMed ID: 29086823
[TBL] [Abstract][Full Text] [Related]
5. Validated LC-MS/MS Method for the Quantification of Ponatinib in Plasma: Application to Metabolic Stability.
Kadi AA; Darwish HW; Attwa MW; Amer SM
PLoS One; 2016; 11(10):e0164967. PubMed ID: 27764191
[TBL] [Abstract][Full Text] [Related]
6. A reliable and stable method for the determination of foretinib in human plasma by LC-MS/MS: Application to metabolic stability investigation and excretion rate.
Attwa MW; Kadi AA; Darwish HW; Amer SM; Alrabiah H
Eur J Mass Spectrom (Chichester); 2018 Aug; 24(4):344-351. PubMed ID: 29629565
[TBL] [Abstract][Full Text] [Related]
7. A reliable and stable method for determination of brigatinib in rat plasma by UPLC-MS/MS: Application to a pharmacokinetic study.
Wen J; Bao S; Cai Y; Zhang B; Wang R; Wang C; Hu G
J Chromatogr B Analyt Technol Biomed Life Sci; 2017 Nov; 1068-1069():84-89. PubMed ID: 29032042
[TBL] [Abstract][Full Text] [Related]
8. Assessment of In Silico and In Vitro Selpercatinib Metabolic Stability in Human Liver Microsomes Using a Validated LC-MS/MS Method.
Attwa MW; AlRabiah H; Mostafa GAE; Bakheit AH; Kadi AA
Molecules; 2023 Mar; 28(6):. PubMed ID: 36985590
[TBL] [Abstract][Full Text] [Related]
9. Quantification of the irreversible fibroblast growth factor receptor inhibitor futibatinib by UPLC-MS/MS: Application to the metabolic stability assay in human liver microsomes for the estimation of its in vitro hepatic intrinsic clearance.
Tang LWT; Chan ECY
J Pharm Biomed Anal; 2022 May; 214():114731. PubMed ID: 35325798
[TBL] [Abstract][Full Text] [Related]
10. A highly efficient and sensitive LC-MS/MS method for the determination of afatinib in human plasma: application to a metabolic stability study.
Kadi AA; Abdelhameed AS; Darwish HW; Attwa MW; Al-Shakliah NS
Biomed Chromatogr; 2016 Aug; 30(8):1248-55. PubMed ID: 26683307
[TBL] [Abstract][Full Text] [Related]
11. LC-MS/MS method for the quantification of masitinib in RLMs matrix and rat urine: application to metabolic stability and excretion rate.
Amer SM; Kadi AA; Darwish HW; Attwa MW
Chem Cent J; 2017 Dec; 11(1):136. PubMed ID: 29274040
[TBL] [Abstract][Full Text] [Related]
12. A rapid and sensitive LC-MS/MS method for evaluation of the absolute oral bioavailability of a novel c-Met tyrosine kinase inhibitor QBH-196 in rats.
Zhang Q; Sun J; Lu T; Zhang J; Wu C; Li L; He Z; Zhao Y; Liu X
Biomed Chromatogr; 2015 Nov; 29(11):1650-6. PubMed ID: 25880630
[TBL] [Abstract][Full Text] [Related]
13. LC-MS/MS Estimation of Rociletinib Levels in Human Liver Microsomes: Application to Metabolic Stability Estimation.
Attwa MW; Abdelhameed AS; Kadi AA
Drug Des Devel Ther; 2021; 15():3915-3925. PubMed ID: 34552321
[TBL] [Abstract][Full Text] [Related]
14. An UPLC-MS/MS method for the quantitation of alectinib in rat plasma.
Huang XX; Li YX; Li XY; Hu XX; Tang PF; Hu GX
J Pharm Biomed Anal; 2017 Jan; 132():227-231. PubMed ID: 27768922
[TBL] [Abstract][Full Text] [Related]
15. LC-MS/MS Estimation of the Anti-Cancer Agent Tandutinib Levels in Human Liver Microsomes: Metabolic Stability Evaluation Assay.
Attwa MW; Abdelhameed AS; Al-Shakliah NS; Kadi AA
Drug Des Devel Ther; 2020; 14():4439-4449. PubMed ID: 33122888
[TBL] [Abstract][Full Text] [Related]
16. Development of an LC-MS/MS Method for Quantification of Sapitinib in Human Liver Microsomes: In Silico and In Vitro Metabolic Stability Evaluation.
Attwa MW; AlRabiah H; Mostafa GAE; Kadi AA
Molecules; 2023 Mar; 28(5):. PubMed ID: 36903565
[TBL] [Abstract][Full Text] [Related]
17. Plasma pharmacokinetics and tissue distribution study of cajaninstilbene acid in rats by liquid chromatography with tandem mass spectrometry.
Hua X; Fu YJ; Zu YG; Wu N; Kong Y; Li J; Peng X; Efferth T
J Pharm Biomed Anal; 2010 Jun; 52(2):273-9. PubMed ID: 20116956
[TBL] [Abstract][Full Text] [Related]
18. Simultaneous determination of selected tyrosine kinase inhibitors with corticosteroids and antiemetics in rat plasma by solid phase extraction and ultra-performance liquid chromatography-tandem mass spectrometry: Application to pharmacokinetic interaction studies.
Maher HM; Alzoman NZ; Shehata SM
J Pharm Biomed Anal; 2016 May; 124():216-227. PubMed ID: 26966895
[TBL] [Abstract][Full Text] [Related]
19. A supported liquid extraction-LC-MS/MS method for determination of GDC-0980 (Apitolisib), a dual small-molecule inhibitor of class 1A phosphoinositide 3-kinase and mammalian target of rapamycin, in human plasma.
Ding X; Li F; McKnight J; Schmidt C; Strooisma K; Shimizu H; Faber K; Ware JA; Dean B
J Pharm Biomed Anal; 2014 Nov; 100():150-156. PubMed ID: 25165011
[TBL] [Abstract][Full Text] [Related]
20. LC-MS/MS method for the quantification of the anti-cancer agent infigratinib: Application for estimation of metabolic stability in human liver microsomes.
Mostafa GAE; Kadi AA; AlMasoud N; Attwa MW; Al-Shakliah NS; AlRabiah H
J Chromatogr B Analyt Technol Biomed Life Sci; 2021 Aug; 1179():122806. PubMed ID: 34325312
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]