BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

544 related articles for article (PubMed ID: 29459277)

  • 1. Targeting G-quadruplex DNA structures in the telomere and oncogene promoter regions by benzimidazole‒carbazole ligands.
    Kaulage MH; Maji B; Pasadi S; Ali A; Bhattacharya S; Muniyappa K
    Eur J Med Chem; 2018 Mar; 148():178-194. PubMed ID: 29459277
    [TBL] [Abstract][Full Text] [Related]  

  • 2. DNA G-Quadruplex in Human Telomeres and Oncogene Promoters: Structures, Functions, and Small Molecule Targeting.
    Chen L; Dickerhoff J; Sakai S; Yang D
    Acc Chem Res; 2022 Sep; 55(18):2628-2646. PubMed ID: 36054116
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Phenanthroline-bis-oxazole ligands for binding and stabilization of G-quadruplexes.
    Medeiros-Silva J; Guédin A; Salgado GF; Mergny JL; Queiroz JA; Cabrita EJ; Cruz C
    Biochim Biophys Acta Gen Subj; 2017 May; 1861(5 Pt B):1281-1292. PubMed ID: 27865994
    [TBL] [Abstract][Full Text] [Related]  

  • 4. FDA-approved drugs selected using virtual screening bind specifically to G-quadruplex DNA.
    Castillo-González D; Pérez-Machado G; Guédin A; Mergny JL; Cabrera-Pérez MA
    Curr Pharm Des; 2013; 19(12):2164-73. PubMed ID: 23016840
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Targeting Canine
    Zorzan E; Da Ros S; Giantin M; Shahidian LZ; Guerra G; Palumbo M; Sissi C; Dacasto M
    J Pharmacol Exp Ther; 2018 Dec; 367(3):461-472. PubMed ID: 30275152
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Benzothiazole hydrazones of furylbenzamides preferentially stabilize c-MYC and c-KIT1 promoter G-quadruplex DNAs.
    Pany SP; Bommisetti P; Diveshkumar KV; Pradeepkumar PI
    Org Biomol Chem; 2016 Jun; 14(24):5779-93. PubMed ID: 27021281
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Design and synthesis of new benzimidazole-carbazole conjugates for the stabilization of human telomeric DNA, telomerase inhibition, and their selective action on cancer cells.
    Maji B; Kumar K; Kaulage M; Muniyappa K; Bhattacharya S
    J Med Chem; 2014 Aug; 57(16):6973-88. PubMed ID: 25062468
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Interaction of G-quadruplexes with nonintercalating duplex-DNA minor groove binding ligands.
    Jain AK; Bhattacharya S
    Bioconjug Chem; 2011 Dec; 22(12):2355-68. PubMed ID: 22074555
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Naphthalene Diimides as Multimodal G-Quadruplex-Selective Ligands.
    Pirota V; Nadai M; Doria F; Richter SN
    Molecules; 2019 Jan; 24(3):. PubMed ID: 30682828
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Perylene and coronene derivatives binding to G-rich promoter oncogene sequences efficiently reduce their expression in cancer cells.
    Micheli E; Altieri A; Cianni L; Cingolani C; Iachettini S; Bianco A; Leonetti C; Cacchione S; Biroccio A; Franceschin M; Rizzo A
    Biochimie; 2016 Jun; 125():223-31. PubMed ID: 27086081
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structure-based optimization of FDA-approved drug methylene blue as a c-myc G-quadruplex DNA stabilizer.
    Chan DS; Yang H; Kwan MH; Cheng Z; Lee P; Bai LP; Jiang ZH; Wong CY; Fong WF; Leung CH; Ma DL
    Biochimie; 2011 Jun; 93(6):1055-64. PubMed ID: 21377506
    [TBL] [Abstract][Full Text] [Related]  

  • 12. In silico identification of novel ligands for G-quadruplex in the c-MYC promoter.
    Kang HJ; Park HJ
    J Comput Aided Mol Des; 2015 Apr; 29(4):339-48. PubMed ID: 25527072
    [TBL] [Abstract][Full Text] [Related]  

  • 13. New dimeric carbazole-benzimidazole mixed ligands for the stabilization of human telomeric G-quadruplex DNA and as telomerase inhibitors. A remarkable influence of the spacer.
    Maji B; Kumar K; Muniyappa K; Bhattacharya S
    Org Biomol Chem; 2015 Aug; 13(30):8335-48. PubMed ID: 26149178
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Telomerase Inhibition and Human Telomeric G-Quadruplex DNA Stabilization by a β-Carboline-Benzimidazole Derivative at Low Concentrations.
    Yadav K; Meka PNR; Sadhu S; Guggilapu SD; Kovvuri J; Kamal A; Srinivas R; Devayani P; Babu BN; Nagesh N
    Biochemistry; 2017 Aug; 56(33):4392-4404. PubMed ID: 28737386
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Topology specific stabilization of promoter over telomeric G-quadruplex DNAs by bisbenzimidazole carboxamide derivatives.
    Dhamodharan V; Harikrishna S; Bhasikuttan AC; Pradeepkumar PI
    ACS Chem Biol; 2015 Mar; 10(3):821-33. PubMed ID: 25495750
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Human telomere, oncogenic promoter and 5'-UTR G-quadruplexes: diverse higher order DNA and RNA targets for cancer therapeutics.
    Patel DJ; Phan AT; Kuryavyi V
    Nucleic Acids Res; 2007; 35(22):7429-55. PubMed ID: 17913750
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Dimeric 1,3-phenylene-bis(piperazinyl benzimidazole)s: synthesis and structure-activity investigations on their binding with human telomeric G-quadruplex DNA and telomerase inhibition properties.
    Jain AK; Paul A; Maji B; Muniyappa K; Bhattacharya S
    J Med Chem; 2012 Apr; 55(7):2981-93. PubMed ID: 22452380
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Specific stabilization of promoter G-Quadruplex DNA by 2,6-disubstituted amidoanthracene-9,10-dione based dimeric distamycin analogues and their selective cancer cell cytotoxicity.
    Roy S; Ali A; Kamra M; Muniyappa K; Bhattacharya S
    Eur J Med Chem; 2020 Jun; 195():112202. PubMed ID: 32302880
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Relative stability of G-quadruplex structures: Interactions between the human Bcl2 promoter region and derivatives of carbazole and diphenylamine.
    Sheu SY; Huang CH; Zhou JK; Yang DY
    Biopolymers; 2014 Oct; 101(10):1038-50. PubMed ID: 24723333
    [TBL] [Abstract][Full Text] [Related]  

  • 20. [G-quadruplex ligands: mechanisms of anticancer action and target binding].
    Il'inskiĭ NS; Varizhuk AM; Beniaminov AD; Puzanov MA; Shchelkina AK; Kaliuzhnyĭ DN
    Mol Biol (Mosk); 2014; 48(6):891-907. PubMed ID: 25845230
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 28.