BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

179 related articles for article (PubMed ID: 29459693)

  • 1. Identification and characterization of SSE15206, a microtubule depolymerizing agent that overcomes multidrug resistance.
    Manzoor S; Bilal A; Khan S; Ullah R; Iftikhar S; Emwas AH; Alazmi M; Gao X; Jawaid A; Saleem RSZ; Faisal A
    Sci Rep; 2018 Feb; 8(1):3305. PubMed ID: 29459693
    [TBL] [Abstract][Full Text] [Related]  

  • 2. CKT0353, a novel microtubule targeting agent, overcomes paclitaxel induced resistance in cancer cells.
    Dinić J; Ríos-Luci C; Karpaviciene I; Cikotiene I; Fernandes MX; Pešić M; Padrón JM
    Invest New Drugs; 2020 Jun; 38(3):584-598. PubMed ID: 31177401
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Structural insight into SSE15206 in complex with tubulin provides a rational design for pyrazolinethioamides as tubulin polymerization inhibitors.
    Ma L; Lei J; Chen H; Huang R; Su T; Feng J; Sun Q
    Future Med Chem; 2022 Jun; 14(11):785-794. PubMed ID: 35506429
    [No Abstract]   [Full Text] [Related]  

  • 4. 2-APCAs, the Novel Microtubule Targeting Agents Active Against Distinct Cancer Cell Lines.
    Boichuk S; Galembikova A; Bikinieva F; Dunaev P; Aukhadieva A; Syuzov K; Zykova S; Igidov N; Ksenofontov A; Bocharov P
    Molecules; 2021 Jan; 26(3):. PubMed ID: 33503939
    [TBL] [Abstract][Full Text] [Related]  

  • 5. CPPF, A Novel Microtubule Targeting Anticancer Agent, Inhibits the Growth of a Wide Variety of Cancers.
    Han HJ; Park C; Hwang J; N R T; Kim SO; Han J; Woo M; B S; Ryoo IJ; Lee KH; Cha-Molstad H; Kwon YT; Kim BY; Soung NK
    Int J Mol Sci; 2020 Jul; 21(13):. PubMed ID: 32645923
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Arsenic trioxide produces polymerization of microtubules and mitotic arrest before apoptosis in human tumor cell lines.
    Ling YH; Jiang JD; Holland JF; Perez-Soler R
    Mol Pharmacol; 2002 Sep; 62(3):529-38. PubMed ID: 12181429
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Systematic Review on Cytotoxic and Anticancer Potential of N-Substituted Isatins as Novel Class of Compounds Useful in Multidrug-Resistant Cancer Therapy: In Silico and In Vitro Analysis.
    Gupta AK; Tulsyan S; Bharadwaj M; Mehrotra R
    Top Curr Chem (Cham); 2019 May; 377(3):15. PubMed ID: 31073777
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A novel oral indoline-sulfonamide agent, N-[1-(4-methoxybenzenesulfonyl)-2,3-dihydro-1H-indol-7-yl]-isonicotinamide (J30), exhibits potent activity against human cancer cells in vitro and in vivo through the disruption of microtubule.
    Liou JP; Hsu KS; Kuo CC; Chang CY; Chang JY
    J Pharmacol Exp Ther; 2007 Oct; 323(1):398-405. PubMed ID: 17660383
    [TBL] [Abstract][Full Text] [Related]  

  • 9. BZML, a novel colchicine binding site inhibitor, overcomes multidrug resistance in A549/Taxol cells by inhibiting P-gp function and inducing mitotic catastrophe.
    Bai Z; Gao M; Zhang H; Guan Q; Xu J; Li Y; Qi H; Li Z; Zuo D; Zhang W; Wu Y
    Cancer Lett; 2017 Aug; 402():81-92. PubMed ID: 28576750
    [TBL] [Abstract][Full Text] [Related]  

  • 10. BPR0L075, a novel synthetic indole compound with antimitotic activity in human cancer cells, exerts effective antitumoral activity in vivo.
    Kuo CC; Hsieh HP; Pan WY; Chen CP; Liou JP; Lee SJ; Chang YL; Chen LT; Chen CT; Chang JY
    Cancer Res; 2004 Jul; 64(13):4621-8. PubMed ID: 15231674
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A-204197, a new tubulin-binding agent with antimitotic activity in tumor cell lines resistant to known microtubule inhibitors.
    Tahir SK; Han EK; Credo B; Jae HS; Pietenpol JA; Scatena CD; Wu-Wong JR; Frost D; Sham H; Rosenberg SH; Ng SC
    Cancer Res; 2001 Jul; 61(14):5480-5. PubMed ID: 11454695
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Indanocine, a microtubule-binding indanone and a selective inducer of apoptosis in multidrug-resistant cancer cells.
    Leoni LM; Hamel E; Genini D; Shih H; Carrera CJ; Cottam HB; Carson DA
    J Natl Cancer Inst; 2000 Feb; 92(3):217-24. PubMed ID: 10655438
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Pseudolaric acid B, a novel microtubule-destabilizing agent that circumvents multidrug resistance phenotype and exhibits antitumor activity in vivo.
    Wong VK; Chiu P; Chung SS; Chow LM; Zhao YZ; Yang BB; Ko BC
    Clin Cancer Res; 2005 Aug; 11(16):6002-11. PubMed ID: 16115945
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A Promising Microtubule Inhibitor Deoxypodophyllotoxin Exhibits Better Efficacy to Multidrug-Resistant Breast Cancer than Paclitaxel via Avoiding Efflux Transport.
    Zang X; Wang G; Cai Q; Zheng X; Zhang J; Chen Q; Wu B; Zhu X; Hao H; Zhou F
    Drug Metab Dispos; 2018 May; 46(5):542-551. PubMed ID: 29523600
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Design, Synthesis, and Biological Evaluation of SSE1806, a Microtubule Destabilizer That Overcomes Multidrug Resistance.
    Firdous F; Riaz S; Furqan M; Fozail S; Fatima K; Pohl SÖ; Doleschall NJ; Myant KB; Kahfi J; Emwas AH; Jaremko M; Chotana GA; Saleem RSZ; Faisal A
    ACS Med Chem Lett; 2023 Oct; 14(10):1369-1377. PubMed ID: 37849542
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Development of a novel class of tubulin inhibitor from desmosdumotin B with a hydroxylated bicyclic B-ring.
    Nakagawa-Goto K; Oda A; Hamel E; Ohkoshi E; Lee KH; Goto M
    J Med Chem; 2015 Mar; 58(5):2378-89. PubMed ID: 25695315
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A genistein derivative, ITB-301, induces microtubule depolymerization and mitotic arrest in multidrug-resistant ovarian cancer.
    Ahmed AA; Goldsmith J; Fokt I; Le XF; Krzysko KA; Lesyng B; Bast RC; Priebe W
    Cancer Chemother Pharmacol; 2011 Oct; 68(4):1033-44. PubMed ID: 21340606
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Salvinal, a novel microtubule inhibitor isolated from Salvia miltiorrhizae Bunge (Danshen), with antimitotic activity in multidrug-sensitive and -resistant human tumor cells.
    Chang JY; Chang CY; Kuo CC; Chen LT; Wein YS; Kuo YH
    Mol Pharmacol; 2004 Jan; 65(1):77-84. PubMed ID: 14722239
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Investigation of anti-tumor mechanisms of K2154: characterization of tubulin isotypes, mitotic arrest and apoptotic machinery.
    Lu PH; Kung FL; Kuo SC; Chueh SC; Guh JH
    Naunyn Schmiedebergs Arch Pharmacol; 2006 Dec; 374(3):223-33. PubMed ID: 17102938
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Targeting of tubulin polymerization and induction of mitotic blockage by Methyl 2-(5-fluoro-2-hydroxyphenyl)-1H-benzo[d]imidazole-5-carboxylate (MBIC) in human cervical cancer HeLa cell.
    Hasanpourghadi M; Karthikeyan C; Pandurangan AK; Looi CY; Trivedi P; Kobayashi K; Tanaka K; Wong WF; Mustafa MR
    J Exp Clin Cancer Res; 2016 Mar; 35():58. PubMed ID: 27030360
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.