270 related articles for article (PubMed ID: 29459793)
1. Consequences of SPAK inactivation on Hyperkalemic Hypertension caused by WNK1 mutations: evidence for differential roles of WNK1 and WNK4.
Rafael C; Soukaseum C; Baudrie V; Frère P; Hadchouel J
Sci Rep; 2018 Feb; 8(1):3249. PubMed ID: 29459793
[TBL] [Abstract][Full Text] [Related]
2. WNK-SPAK-NCC cascade revisited: WNK1 stimulates the activity of the Na-Cl cotransporter via SPAK, an effect antagonized by WNK4.
Chávez-Canales M; Zhang C; Soukaseum C; Moreno E; Pacheco-Alvarez D; Vidal-Petiot E; Castañeda-Bueno M; Vázquez N; Rojas-Vega L; Meermeier NP; Rogers S; Jeunemaitre X; Yang CL; Ellison DH; Gamba G; Hadchouel J
Hypertension; 2014 Nov; 64(5):1047-53. PubMed ID: 25113964
[TBL] [Abstract][Full Text] [Related]
3. Kidney-specific WNK1 isoform (KS-WNK1) is a potent activator of WNK4 and NCC.
Argaiz ER; Chavez-Canales M; Ostrosky-Frid M; Rodríguez-Gama A; Vázquez N; Gonzalez-Rodriguez X; Garcia-Valdes J; Hadchouel J; Ellison D; Gamba G
Am J Physiol Renal Physiol; 2018 Sep; 315(3):F734-F745. PubMed ID: 29846116
[TBL] [Abstract][Full Text] [Related]
4. Mutation affecting the conserved acidic WNK1 motif causes inherited hyperkalemic hyperchloremic acidosis.
Louis-Dit-Picard H; Kouranti I; Rafael C; Loisel-Ferreira I; Chavez-Canales M; Abdel-Khalek W; Argaiz ER; Baron S; Vacle S; Migeon T; Coleman R; Do Cruzeiro M; Hureaux M; Thurairajasingam N; Decramer S; Girerd X; O'Shaugnessy K; Mulatero P; Roussey G; Tack I; Unwin R; Vargas-Poussou R; Staub O; Grimm R; Welling PA; Gamba G; Clauser E; Hadchouel J; Jeunemaitre X
J Clin Invest; 2020 Dec; 130(12):6379-6394. PubMed ID: 32790646
[TBL] [Abstract][Full Text] [Related]
5. WNK4 is indispensable for the pathogenesis of pseudohypoaldosteronism type II caused by mutant KLHL3.
Susa K; Sohara E; Takahashi D; Okado T; Rai T; Uchida S
Biochem Biophys Res Commun; 2017 Sep; 491(3):727-732. PubMed ID: 28743496
[TBL] [Abstract][Full Text] [Related]
6. The WNK1 and WNK4 protein kinases that are mutated in Gordon's hypertension syndrome phosphorylate and activate SPAK and OSR1 protein kinases.
Vitari AC; Deak M; Morrice NA; Alessi DR
Biochem J; 2005 Oct; 391(Pt 1):17-24. PubMed ID: 16083423
[TBL] [Abstract][Full Text] [Related]
7. Phenotypes of pseudohypoaldosteronism type II caused by the WNK4 D561A missense mutation are dependent on the WNK-OSR1/SPAK kinase cascade.
Chiga M; Rafiqi FH; Alessi DR; Sohara E; Ohta A; Rai T; Sasaki S; Uchida S
J Cell Sci; 2011 May; 124(Pt 9):1391-5. PubMed ID: 21486947
[TBL] [Abstract][Full Text] [Related]
8. Decreased KLHL3 expression is involved in the activation of WNK-OSR1/SPAK-NCC cascade in type 1 diabetic mice.
Guo Q; Zhang Y; Jiang GR; Zhang C
Pflugers Arch; 2021 Feb; 473(2):185-196. PubMed ID: 33432425
[TBL] [Abstract][Full Text] [Related]
9. SPAK deficiency corrects pseudohypoaldosteronism II caused by WNK4 mutation.
Chu PY; Cheng CJ; Wu YC; Fang YW; Chau T; Uchida S; Sasaki S; Yang SS; Lin SH
PLoS One; 2013; 8(9):e72969. PubMed ID: 24039833
[TBL] [Abstract][Full Text] [Related]
10. Dysregulation of the WNK4-SPAK/OSR1 pathway has a minor effect on baseline NKCC2 phosphorylation.
Maeoka Y; Nguyen LT; Sharma A; Cornelius RJ; Su XT; Gutierrez MR; Carbajal-Contreras H; Castañeda-Bueno M; Gamba G; McCormick JA
Am J Physiol Renal Physiol; 2024 Jan; 326(1):F39-F56. PubMed ID: 37881876
[TBL] [Abstract][Full Text] [Related]
11. Impaired degradation of WNK1 and WNK4 kinases causes PHAII in mutant KLHL3 knock-in mice.
Susa K; Sohara E; Rai T; Zeniya M; Mori Y; Mori T; Chiga M; Nomura N; Nishida H; Takahashi D; Isobe K; Inoue Y; Takeishi K; Takeda N; Sasaki S; Uchida S
Hum Mol Genet; 2014 Oct; 23(19):5052-60. PubMed ID: 24821705
[TBL] [Abstract][Full Text] [Related]
12. Effect of heterozygous deletion of WNK1 on the WNK-OSR1/ SPAK-NCC/NKCC1/NKCC2 signal cascade in the kidney and blood vessels.
Susa K; Kita S; Iwamoto T; Yang SS; Lin SH; Ohta A; Sohara E; Rai T; Sasaki S; Alessi DR; Uchida S
Clin Exp Nephrol; 2012 Aug; 16(4):530-8. PubMed ID: 22294159
[TBL] [Abstract][Full Text] [Related]
13. Role of KLHL3 and dietary K
Ostrosky-Frid M; Chávez-Canales M; Zhang J; Andrukhova O; Argaiz ER; Lerdo-de-Tejada F; Murillo-de-Ozores A; Sanchez-Navarro A; Rojas-Vega L; Bobadilla NA; Vazquez N; Castañeda-Bueno M; Alessi DR; Gamba G
Am J Physiol Renal Physiol; 2021 May; 320(5):F734-F747. PubMed ID: 33682442
[TBL] [Abstract][Full Text] [Related]
14. The CUL3-KLHL3 E3 ligase complex mutated in Gordon's hypertension syndrome interacts with and ubiquitylates WNK isoforms: disease-causing mutations in KLHL3 and WNK4 disrupt interaction.
Ohta A; Schumacher FR; Mehellou Y; Johnson C; Knebel A; Macartney TJ; Wood NT; Alessi DR; Kurz T
Biochem J; 2013 Apr; 451(1):111-22. PubMed ID: 23387299
[TBL] [Abstract][Full Text] [Related]
15. WNK1 regulates phosphorylation of cation-chloride-coupled cotransporters via the STE20-related kinases, SPAK and OSR1.
Moriguchi T; Urushiyama S; Hisamoto N; Iemura S; Uchida S; Natsume T; Matsumoto K; Shibuya H
J Biol Chem; 2005 Dec; 280(52):42685-93. PubMed ID: 16263722
[TBL] [Abstract][Full Text] [Related]
16. Degradation by Cullin 3 and effect on WNK kinases suggest a role of KLHL2 in the pathogenesis of Familial Hyperkalemic Hypertension.
Zhang C; Meermeier NP; Terker AS; Blankenstein KI; Singer JD; Hadchouel J; Ellison DH; Yang CL
Biochem Biophys Res Commun; 2016 Jan; 469(1):44-48. PubMed ID: 26607111
[TBL] [Abstract][Full Text] [Related]
17. Dietary electrolyte-driven responses in the renal WNK kinase pathway in vivo.
O'Reilly M; Marshall E; Macgillivray T; Mittal M; Xue W; Kenyon CJ; Brown RW
J Am Soc Nephrol; 2006 Sep; 17(9):2402-13. PubMed ID: 16899520
[TBL] [Abstract][Full Text] [Related]
18. WNK1-related Familial Hyperkalemic Hypertension results from an increased expression of L-WNK1 specifically in the distal nephron.
Vidal-Petiot E; Elvira-Matelot E; Mutig K; Soukaseum C; Baudrie V; Wu S; Cheval L; Huc E; Cambillau M; Bachmann S; Doucet A; Jeunemaitre X; Hadchouel J
Proc Natl Acad Sci U S A; 2013 Aug; 110(35):14366-71. PubMed ID: 23940364
[TBL] [Abstract][Full Text] [Related]
19. The interplay of renal potassium and sodium handling in blood pressure regulation: critical role of the WNK-SPAK-NCC pathway.
Wu A; Wolley M; Stowasser M
J Hum Hypertens; 2019 Jul; 33(7):508-523. PubMed ID: 30723251
[TBL] [Abstract][Full Text] [Related]
20. Combined Kelch-like 3 and Cullin 3 Degradation is a Central Mechanism in Familial Hyperkalemic Hypertension in Mice.
Maeoka Y; Ferdaus MZ; Cornelius RJ; Sharma A; Su XT; Miller LN; Robertson JA; Gurley SB; Yang CL; Ellison DH; McCormick JA
J Am Soc Nephrol; 2022 Mar; 33(3):584-600. PubMed ID: 35064051
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
