These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

137 related articles for article (PubMed ID: 29460311)

  • 1. Enhancing cytochrome P450-mediated non-natural cyclopropanation by mutation of a conserved second-shell residue.
    Gober JG; Rydeen AE; Schwochert TD; Gibson-O'Grady EJ; Brustad EM
    Biotechnol Bioeng; 2018 Jun; 115(6):1416-1426. PubMed ID: 29460311
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Non-natural olefin cyclopropanation catalyzed by diverse cytochrome P450s and other hemoproteins.
    Heel T; McIntosh JA; Dodani SC; Meyerowitz JT; Arnold FH
    Chembiochem; 2014 Nov; 15(17):2556-62. PubMed ID: 25294253
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Mutating a Highly Conserved Residue in Diverse Cytochrome P450s Facilitates Diastereoselective Olefin Cyclopropanation.
    Gober JG; Rydeen AE; Gibson-O'Grady EJ; Leuthaeuser JB; Fetrow JS; Brustad EM
    Chembiochem; 2016 Mar; 17(5):394-7. PubMed ID: 26690878
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Identification of Mechanism-Based Inactivation in P450-Catalyzed Cyclopropanation Facilitates Engineering of Improved Enzymes.
    Renata H; Lewis RD; Sweredoski MJ; Moradian A; Hess S; Wang ZJ; Arnold FH
    J Am Chem Soc; 2016 Sep; 138(38):12527-33. PubMed ID: 27573353
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Improved cyclopropanation activity of histidine-ligated cytochrome P450 enables the enantioselective formal synthesis of levomilnacipran.
    Wang ZJ; Renata H; Peck NE; Farwell CC; Coelho PS; Arnold FH
    Angew Chem Int Ed Engl; 2014 Jun; 53(26):6810-3. PubMed ID: 24802161
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Development of an improved Amplex Red peroxidation activity assay for screening cytochrome P450 variants and identification of a novel mutant of the thermophilic CYP119.
    Başlar MS; Sakallı T; Güralp G; Kestevur Doğru E; Haklı E; Surmeli NB
    J Biol Inorg Chem; 2020 Oct; 25(7):949-962. PubMed ID: 32924072
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Orthogonal Expression of an Artificial Metalloenzyme for Abiotic Catalysis.
    Reynolds EW; Schwochert TD; McHenry MW; Watters JW; Brustad EM
    Chembiochem; 2017 Dec; 18(24):2380-2384. PubMed ID: 29024391
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Hijacking Chemical Reactions of P450 Enzymes for Altered Chemical Reactions and Asymmetric Synthesis.
    Rajakumara E; Saniya D; Bajaj P; Rajeshwari R; Giri J; Davari MD
    Int J Mol Sci; 2022 Dec; 24(1):. PubMed ID: 36613657
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Theoretical Insights into the Mechanism and Stereoselectivity of Olefin Cyclopropanation Catalyzed by Two Engineered Cytochrome P450 Enzymes.
    Su H; Ma G; Liu Y
    Inorg Chem; 2018 Sep; 57(18):11738-11745. PubMed ID: 30156099
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Recent developments in the application of P450 based biocatalysts.
    Wei Y; Ang EL; Zhao H
    Curr Opin Chem Biol; 2018 Apr; 43():1-7. PubMed ID: 29100098
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Olefin cyclopropanation via carbene transfer catalyzed by engineered cytochrome P450 enzymes.
    Coelho PS; Brustad EM; Kannan A; Arnold FH
    Science; 2013 Jan; 339(6117):307-10. PubMed ID: 23258409
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Role of cytochrome B5 in modulating peroxide-supported cyp3a4 activity: evidence for a conformational transition and cytochrome P450 heterogeneity.
    Kumar S; Davydov DR; Halpert JR
    Drug Metab Dispos; 2005 Aug; 33(8):1131-6. PubMed ID: 15870379
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Engineering bacterial cytochrome P450 (P450) BM3 into a prototype with human P450 enzyme activity using indigo formation.
    Park SH; Kim DH; Kim D; Kim DH; Jung HC; Pan JG; Ahn T; Kim D; Yun CH
    Drug Metab Dispos; 2010 May; 38(5):732-9. PubMed ID: 20100815
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Cytochrome P450 monooxygenases: an update on perspectives for synthetic application.
    Urlacher VB; Girhard M
    Trends Biotechnol; 2012 Jan; 30(1):26-36. PubMed ID: 21782265
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Application of engineered cytochrome P450 mutants as biocatalysts for the synthesis of benzylic and aromatic metabolites of fenamic acid NSAIDs.
    Venkataraman H; Verkade-Vreeker MC; Capoferri L; Geerke DP; Vermeulen NP; Commandeur JN
    Bioorg Med Chem; 2014 Oct; 22(20):5613-20. PubMed ID: 24999003
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Engineering cytochrome c peroxidase into cytochrome P450: a proximal effect on heme-thiolate ligation.
    Sigman JA; Pond AE; Dawson JH; Lu Y
    Biochemistry; 1999 Aug; 38(34):11122-9. PubMed ID: 10460168
    [TBL] [Abstract][Full Text] [Related]  

  • 17. An integrated screening system for the selection of exemplary substrates for natural and engineered cytochrome P450s.
    Kanoh N; Kawamata-Asano A; Suzuki K; Takahashi Y; Miyazawa T; Nakamura T; Moriya T; Hirano H; Osada H; Iwabuchi Y; Takahashi S
    Sci Rep; 2019 Dec; 9(1):18023. PubMed ID: 31792277
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Biocatalytic Asymmetric Cyclopropanations via Enzyme-Bound Iminium Ion Intermediates.
    Kunzendorf A; Xu G; Saifuddin M; Saravanan T; Poelarends GJ
    Angew Chem Int Ed Engl; 2021 Nov; 60(45):24059-24063. PubMed ID: 34490955
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Cytochrome P450(cin) (CYP176A1) D241N: investigating the role of the conserved acid in the active site of cytochrome P450s.
    Stok JE; Yamada S; Farlow AJ; Slessor KE; De Voss JJ
    Biochim Biophys Acta; 2013 Mar; 1834(3):688-96. PubMed ID: 23305928
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Strategies for Substrate-Regulated P450 Catalysis: From Substrate Engineering to Co-catalysis.
    Xu J; Wang C; Cong Z
    Chemistry; 2019 May; 25(28):6853-6863. PubMed ID: 30698852
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.