143 related articles for article (PubMed ID: 29461059)
1. Role of Dimers in the cAMP-Dependent Activation of Hyperpolarization-Activated Cyclic-Nucleotide-Modulated (HCN) Ion Channels.
VanSchouwen B; Melacini G
J Phys Chem B; 2018 Mar; 122(8):2177-2190. PubMed ID: 29461059
[TBL] [Abstract][Full Text] [Related]
2. Role of Dynamics in the Autoinhibition and Activation of the Hyperpolarization-activated Cyclic Nucleotide-modulated (HCN) Ion Channels.
VanSchouwen B; Akimoto M; Sayadi M; Fogolari F; Melacini G
J Biol Chem; 2015 Jul; 290(29):17642-17654. PubMed ID: 25944904
[TBL] [Abstract][Full Text] [Related]
3. The structure of the apo cAMP-binding domain of HCN4 - a stepping stone toward understanding the cAMP-dependent modulation of the hyperpolarization-activated cyclic-nucleotide-gated ion channels.
Akimoto M; VanSchouwen B; Melacini G
FEBS J; 2018 Jun; 285(12):2182-2192. PubMed ID: 29444387
[TBL] [Abstract][Full Text] [Related]
4. Structural Basis of Tonic Inhibition by Dimers of Dimers in Hyperpolarization-Activated Cyclic-Nucleotide-Modulated (HCN) Ion Channels.
VanSchouwen B; Melacini G
J Phys Chem B; 2016 Oct; 120(42):10936-10950. PubMed ID: 27690448
[TBL] [Abstract][Full Text] [Related]
5. A mechanism for the auto-inhibition of hyperpolarization-activated cyclic nucleotide-gated (HCN) channel opening and its relief by cAMP.
Akimoto M; Zhang Z; Boulton S; Selvaratnam R; VanSchouwen B; Gloyd M; Accili EA; Lange OF; Melacini G
J Biol Chem; 2014 Aug; 289(32):22205-20. PubMed ID: 24878962
[TBL] [Abstract][Full Text] [Related]
6. The HCN domain is required for HCN channel cell-surface expression and couples voltage- and cAMP-dependent gating mechanisms.
Wang ZJ; Blanco I; Hayoz S; Brelidze TI
J Biol Chem; 2020 Jun; 295(24):8164-8173. PubMed ID: 32341127
[TBL] [Abstract][Full Text] [Related]
7. Free energy landscape remodeling of the cardiac pacemaker channel explains the molecular basis of familial sinus bradycardia.
Boulton S; Akimoto M; Akbarizadeh S; Melacini G
J Biol Chem; 2017 Apr; 292(15):6414-6428. PubMed ID: 28174302
[TBL] [Abstract][Full Text] [Related]
8. The HCN domain couples voltage gating and cAMP response in hyperpolarization-activated cyclic nucleotide-gated channels.
Porro A; Saponaro A; Gasparri F; Bauer D; Gross C; Pisoni M; Abbandonato G; Hamacher K; Santoro B; Thiel G; Moroni A
Elife; 2019 Nov; 8():. PubMed ID: 31769408
[TBL] [Abstract][Full Text] [Related]
9. Propofol, an Anesthetic Agent, Inhibits HCN Channels through the Allosteric Modulation of the cAMP-Dependent Gating Mechanism.
Shimizu M; Mi X; Toyoda F; Kojima A; Ding WG; Fukushima Y; Omatsu-Kanbe M; Kitagawa H; Matsuura H
Biomolecules; 2022 Apr; 12(4):. PubMed ID: 35454159
[TBL] [Abstract][Full Text] [Related]
10. A synthetic peptide that prevents cAMP regulation in mammalian hyperpolarization-activated cyclic nucleotide-gated (HCN) channels.
Saponaro A; Cantini F; Porro A; Bucchi A; DiFrancesco D; Maione V; Donadoni C; Introini B; Mesirca P; Mangoni ME; Thiel G; Banci L; Santoro B; Moroni A
Elife; 2018 Jun; 7():. PubMed ID: 29923826
[TBL] [Abstract][Full Text] [Related]
11. A reduced mechanical model for cAMP-modulated gating in HCN channels.
Weißgraeber S; Saponaro A; Thiel G; Hamacher K
Sci Rep; 2017 Jan; 7():40168. PubMed ID: 28074902
[TBL] [Abstract][Full Text] [Related]
12. Structural and functional approaches to studying cAMP regulation of HCN channels.
Saponaro A; Thiel G; Moroni A
Biochem Soc Trans; 2021 Dec; 49(6):2573-2579. PubMed ID: 34812892
[TBL] [Abstract][Full Text] [Related]
13. Allosteric signaling in C-linker and cyclic nucleotide-binding domain of HCN2 channels.
Pfleger C; Kusch J; Kondapuram M; Schwabe T; Sattler C; Benndorf K; Gohlke H
Biophys J; 2021 Mar; 120(5):950-963. PubMed ID: 33515603
[TBL] [Abstract][Full Text] [Related]
14. Tetramerization dynamics of C-terminal domain underlies isoform-specific cAMP gating in hyperpolarization-activated cyclic nucleotide-gated channels.
Lolicato M; Nardini M; Gazzarrini S; Möller S; Bertinetti D; Herberg FW; Bolognesi M; Martin H; Fasolini M; Bertrand JA; Arrigoni C; Thiel G; Moroni A
J Biol Chem; 2011 Dec; 286(52):44811-20. PubMed ID: 22006928
[TBL] [Abstract][Full Text] [Related]
15. Mechanical transduction of cytoplasmic-to-transmembrane-domain movements in a hyperpolarization-activated cyclic nucleotide-gated cation channel.
Gross C; Saponaro A; Santoro B; Moroni A; Thiel G; Hamacher K
J Biol Chem; 2018 Aug; 293(33):12908-12918. PubMed ID: 29936413
[TBL] [Abstract][Full Text] [Related]
16. Regulation of HCN Ion Channels by Non-canonical Cyclic Nucleotides.
VanSchouwen B; Melacini G
Handb Exp Pharmacol; 2017; 238():123-133. PubMed ID: 28181007
[TBL] [Abstract][Full Text] [Related]
17. Structural basis for the mutual antagonism of cAMP and TRIP8b in regulating HCN channel function.
Saponaro A; Pauleta SR; Cantini F; Matzapetakis M; Hammann C; Donadoni C; Hu L; Thiel G; Banci L; Santoro B; Moroni A
Proc Natl Acad Sci U S A; 2014 Oct; 111(40):14577-82. PubMed ID: 25197093
[TBL] [Abstract][Full Text] [Related]
18. Anisotropic Network Analysis of Open/Closed HCN4 Channel Advocates Asymmetric Subunit Cooperativity in cAMP Modulation of Gating.
Kunzmann P; Krumbach JH; Saponaro A; Moroni A; Thiel G; Hamacher K
J Chem Inf Model; 2024 Jun; 64(12):4727-4738. PubMed ID: 38830626
[TBL] [Abstract][Full Text] [Related]
19. Functional and structural characterization of interactions between opposite subunits in HCN pacemaker channels.
Kondapuram M; Frieg B; Yüksel S; Schwabe T; Sattler C; Lelle M; Schweinitz A; Schmauder R; Benndorf K; Gohlke H; Kusch J
Commun Biol; 2022 May; 5(1):430. PubMed ID: 35534535
[TBL] [Abstract][Full Text] [Related]
20.
Leypold T; Bonus M; Spiegelhalter F; Schwede F; Schwabe T; Gohlke H; Kusch J
J Biol Chem; 2019 Nov; 294(47):17978-17987. PubMed ID: 31615893
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
