These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

144 related articles for article (PubMed ID: 29470101)

  • 1. Ebselen Reversibly Inhibits Human Glutamate Dehydrogenase at the Catalytic Site.
    Jin Y; Li D; Lu S; Zhao H; Chen Z; Hou W; Ruan BH
    Assay Drug Dev Technol; 2018; 16(2):115-122. PubMed ID: 29470101
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Ebselen: Mechanisms of Glutamate Dehydrogenase and Glutaminase Enzyme Inhibition.
    Yu Y; Jin Y; Zhou J; Ruan H; Zhao H; Lu S; Zhang Y; Li D; Ji X; Ruan BH
    ACS Chem Biol; 2017 Dec; 12(12):3003-3011. PubMed ID: 29072450
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Propylselen inhibits cancer cell growth by targeting glutamate dehydrogenase at the NADP
    Hou W; Lu S; Zhao H; Yu Y; Xu H; Yu B; Su L; Lin C; Ruan BH
    Biochem Biophys Res Commun; 2019 Jan; 509(1):262-267. PubMed ID: 30583861
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Identification of ebselen as a potent inhibitor of insulin degrading enzyme by a drug repurposing screening.
    Leroux F; Bosc D; Beghyn T; Hermant P; Warenghem S; Landry V; Pottiez V; Guillaume V; Charton J; Herledan A; Urata S; Liang W; Sheng L; Tang WJ; Deprez B; Deprez-Poulain R
    Eur J Med Chem; 2019 Oct; 179():557-566. PubMed ID: 31276900
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Biomolecular Interaction Assays Identified Dual Inhibitors of Glutaminase and Glutamate Dehydrogenase That Disrupt Mitochondrial Function and Prevent Growth of Cancer Cells.
    Zhu M; Fang J; Zhang J; Zhang Z; Xie J; Yu Y; Ruan JJ; Chen Z; Hou W; Yang G; Su W; Ruan BH
    Anal Chem; 2017 Feb; 89(3):1689-1696. PubMed ID: 28208301
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The selenazal drug ebselen potently inhibits indoleamine 2,3-dioxygenase by targeting enzyme cysteine residues.
    Terentis AC; Freewan M; Sempértegui Plaza TS; Raftery MJ; Stocker R; Thomas SR
    Biochemistry; 2010 Jan; 49(3):591-600. PubMed ID: 20000778
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Mono-sulfonated tetrazolium salt based NAD(P)H detection reagents suitable for dehydrogenase and real-time cell viability assays.
    Zhang W; Zhu M; Wang F; Cao D; Ruan JJ; Su W; Ruan BH
    Anal Biochem; 2016 Sep; 509():33-40. PubMed ID: 27387057
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Expression, purification and characterization of human glutamate dehydrogenase (GDH) allosteric regulatory mutations.
    Fang J; Hsu BY; MacMullen CM; Poncz M; Smith TJ; Stanley CA
    Biochem J; 2002 Apr; 363(Pt 1):81-7. PubMed ID: 11903050
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Inactivation of the Mycobacterium tuberculosis antigen 85 complex by covalent, allosteric inhibitors.
    Favrot L; Lajiness DH; Ronning DR
    J Biol Chem; 2014 Sep; 289(36):25031-40. PubMed ID: 25028518
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Horseradish peroxidase inhibition and antioxidant activity of ebselen and related organoselenium compounds.
    Mishra B; Priyadarsini KI; Mohan H; Mugesh G
    Bioorg Med Chem Lett; 2006 Oct; 16(20):5334-8. PubMed ID: 16919452
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Novel inhibitors complexed with glutamate dehydrogenase: allosteric regulation by control of protein dynamics.
    Li M; Smith CJ; Walker MT; Smith TJ
    J Biol Chem; 2009 Aug; 284(34):22988-3000. PubMed ID: 19531491
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Exploring Covalent Allosteric Inhibition of Antigen 85C from Mycobacterium tuberculosis by Ebselen Derivatives.
    Goins CM; Dajnowicz S; Thanna S; Sucheck SJ; Parks JM; Ronning DR
    ACS Infect Dis; 2017 May; 3(5):378-387. PubMed ID: 28285521
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Developing selective histone deacetylases (HDACs) inhibitors through ebselen and analogs.
    Wang Y; Wallach J; Duane S; Wang Y; Wu J; Wang J; Adejare A; Ma H
    Drug Des Devel Ther; 2017; 11():1369-1382. PubMed ID: 28496307
    [TBL] [Abstract][Full Text] [Related]  

  • 14. High throughput screening reveals several new classes of glutamate dehydrogenase inhibitors.
    Li M; Allen A; Smith TJ
    Biochemistry; 2007 Dec; 46(51):15089-102. PubMed ID: 18044977
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Ebselen, a Small-Molecule Capsid Inhibitor of HIV-1 Replication.
    Thenin-Houssier S; de Vera IM; Pedro-Rosa L; Brady A; Richard A; Konnick B; Opp S; Buffone C; Fuhrmann J; Kota S; Billack B; Pietka-Ottlik M; Tellinghuisen T; Choe H; Spicer T; Scampavia L; Diaz-Griffero F; Kojetin DJ; Valente ST
    Antimicrob Agents Chemother; 2016 Apr; 60(4):2195-208. PubMed ID: 26810656
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Glutamate Dehydrogenase as a Promising Target for Hyperinsulinism Hyperammonemia Syndrome Therapy.
    Bian Y; Hou W; Chen X; Fang J; Xu N; Ruan BH
    Curr Med Chem; 2022; 29(15):2652-2672. PubMed ID: 34525914
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The structure and allosteric regulation of mammalian glutamate dehydrogenase.
    Li M; Li C; Allen A; Stanley CA; Smith TJ
    Arch Biochem Biophys; 2012 Mar; 519(2):69-80. PubMed ID: 22079166
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Molecular actions of ebselen--an antiinflammatory antioxidant.
    Schewe T
    Gen Pharmacol; 1995 Oct; 26(6):1153-69. PubMed ID: 7590103
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Substitution of Ser for Arg-443 in the regulatory domain of human housekeeping (GLUD1) glutamate dehydrogenase virtually abolishes basal activity and markedly alters the activation of the enzyme by ADP and L-leucine.
    Zaganas I; Spanaki C; Karpusas M; Plaitakis A
    J Biol Chem; 2002 Nov; 277(48):46552-8. PubMed ID: 12324473
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Targeting the Mycobacterium tuberculosis transpeptidase Ldt
    de Munnik M; Lohans CT; Lang PA; Langley GW; Malla TR; Tumber A; Schofield CJ; Brem J
    Chem Commun (Camb); 2019 Aug; 55(69):10214-10217. PubMed ID: 31380528
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.