BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

112 related articles for article (PubMed ID: 29471040)

  • 1. Biodistribution, activation, and retention of proinsulin-transferrin fusion protein in the liver: Mechanism of liver-targeting as an insulin prodrug.
    Liu Y; Wang HY; Zhou L; Su Y; Shen WC
    J Control Release; 2018 Apr; 275():186-191. PubMed ID: 29471040
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Receptor-mediated activation of a proinsulin-transferrin fusion protein in hepatoma cells.
    Wang Y; Chen YS; Zaro JL; Shen WC
    J Control Release; 2011 Nov; 155(3):386-92. PubMed ID: 21756950
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Proinsulin-Transferrin Fusion Protein Exhibits a Prolonged and Selective Effect on the Control of Hepatic Glucose Production in an Experimental Model of Type 1 Diabetes.
    Shao J; Zaro JL; Shen WC
    Mol Pharm; 2016 Aug; 13(8):2641-6. PubMed ID: 27280852
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Proinsulin-transferrin fusion protein as a novel long-acting insulin analog for the inhibition of hepatic glucose production.
    Wang Y; Shao J; Zaro JL; Shen WC
    Diabetes; 2014 May; 63(5):1779-88. PubMed ID: 24353179
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Enhanced insulin receptor interaction by a bifunctional insulin-transferrin fusion protein: an approach to overcome insulin resistance.
    Liu Y; Wang HY; Shao J; Zaro JL; Shen WC
    Sci Rep; 2020 May; 10(1):7724. PubMed ID: 32382087
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Characterization and Oral Delivery of Proinsulin-Transferrin Fusion Protein Expressed Using ExpressTec.
    Chen YS; Zaro JL; Zhang D; Huang N; Simon A; Shen WC
    Int J Mol Sci; 2018 Jan; 19(2):. PubMed ID: 29373562
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Tyrphostin-8 enhances transferrin receptor-mediated transcytosis in Caco-2- cells and inreases hypoglycemic effect of orally administered insulin-transferrin conjugate in diabetic rats.
    Xia CQ; Shen WC
    Pharm Res; 2001 Feb; 18(2):191-5. PubMed ID: 11405290
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Hypoglycemic effect of insulin-transferrin conjugate in streptozotocin-induced diabetic rats.
    Xia CQ; Wang J; Shen WC
    J Pharmacol Exp Ther; 2000 Nov; 295(2):594-600. PubMed ID: 11046093
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Effects of receptor binding on plasma half-life of bifunctional transferrin fusion proteins.
    Chen X; Lee HF; Zaro JL; Shen WC
    Mol Pharm; 2011 Apr; 8(2):457-65. PubMed ID: 21291258
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Tumor cell targeting of transferrin-PEG-TNF-alpha conjugate via a receptor-mediated delivery system: design, synthesis, and biological evaluation.
    Jiang YY; Liu C; Hong MH; Zhu SJ; Pei YY
    Bioconjug Chem; 2007; 18(1):41-9. PubMed ID: 17226956
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Transcellular delivery of an insulin-transferrin conjugate in enterocyte-like Caco-2 cells.
    Shah D; Shen WC
    J Pharm Sci; 1996 Dec; 85(12):1306-11. PubMed ID: 8961144
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Comparison of monomeric and oligomeric transferrin as potential carrier in oral delivery of protein drugs.
    Lim CJ; Shen WC
    J Control Release; 2005 Sep; 106(3):273-86. PubMed ID: 15964654
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Cell itinerary and metabolic fate of proinsulin in rat liver: in vivo and in vitro studies.
    Desbuquois B; Chauvet G; Kouach M; Authier F
    Endocrinology; 2003 Dec; 144(12):5308-21. PubMed ID: 12970169
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Fusion of proinsulin-producing bone marrow-derived cells with hepatocytes in diabetes.
    Fujimiya M; Kojima H; Ichinose M; Arai R; Kimura H; Kashiwagi A; Chan L
    Proc Natl Acad Sci U S A; 2007 Mar; 104(10):4030-5. PubMed ID: 17360472
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Targeting of transferrin receptors in nude mice bearing A431 and LS174T xenografts with [18F]holo-transferrin: permeability and receptor dependence.
    Aloj L; Jogoda E; Lang L; Caracò C; Neumann RD; Sung C; Eckelman WC
    J Nucl Med; 1999 Sep; 40(9):1547-55. PubMed ID: 10492378
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Active tumor-targeted delivery of PEG-protein via transferrin-transferrin-receptor system.
    Jiang Y; Tang G; Hong M; Zhu S; Fang C; Shi B; Pei Y
    J Drug Target; 2007 Dec; 15(10):672-83. PubMed ID: 18041635
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Transferrin-conjugated micelles: enhanced accumulation and antitumor effect for transferrin-receptor-overexpressing cancer models.
    Yue J; Liu S; Wang R; Hu X; Xie Z; Huang Y; Jing X
    Mol Pharm; 2012 Jul; 9(7):1919-31. PubMed ID: 22616905
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Tissue barriers and novel approaches to achieve hepatoselectivity of subcutaneously-injected insulin therapeutics.
    Shao J; Zaro JL; Shen WC
    Tissue Barriers; 2016; 4(2):e1156804. PubMed ID: 27358753
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Increased brain uptake of targeted nanoparticles by adding an acid-cleavable linkage between transferrin and the nanoparticle core.
    Clark AJ; Davis ME
    Proc Natl Acad Sci U S A; 2015 Oct; 112(40):12486-91. PubMed ID: 26392563
    [TBL] [Abstract][Full Text] [Related]  

  • 20. [Transferrin receptor and iron deposition pattern in the hepatic lobules of the iron-deficient and iron-overloaded rats].
    Lu J; Hayashi K; Hu X
    Zhonghua Bing Li Xue Za Zhi; 1995 Apr; 24(2):75-7. PubMed ID: 7788730
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.