These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
2. The natural mutation by deletion of Lys9 in the thrombin A-chain affects the pKa value of catalytic residues, the overall enzyme's stability and conformational transitions linked to Na+ binding. De Cristofaro R; Carotti A; Akhavan S; Palla R; Peyvandi F; Altomare C; Mannucci PM FEBS J; 2006 Jan; 273(1):159-69. PubMed ID: 16367756 [TBL] [Abstract][Full Text] [Related]
3. Light Chain Mutation Effects on the Dynamics of Thrombin. Wu D; Xiao J; Salsbury FR J Chem Inf Model; 2021 Feb; 61(2):950-965. PubMed ID: 33450154 [TBL] [Abstract][Full Text] [Related]
4. A natural prothrombin mutant reveals an unexpected influence of A-chain structure on the activity of human alpha-thrombin. De Cristofaro R; Akhavan S; Altomare C; Carotti A; Peyvandi F; Mannucci PM J Biol Chem; 2004 Mar; 279(13):13035-43. PubMed ID: 14722067 [TBL] [Abstract][Full Text] [Related]
5. Toward understanding allosteric activation of thrombin: a conjecture for important roles of unbound Na(+) molecules around thrombin. Kurisaki I; Takayanagi M; Nagaoka M J Phys Chem B; 2015 Mar; 119(9):3635-42. PubMed ID: 25654267 [TBL] [Abstract][Full Text] [Related]
18. The molecular environment of the Na+ binding site of thrombin. Zhang E; Tulinsky A Biophys Chem; 1997 Jan; 63(2-3):185-200. PubMed ID: 9108691 [TBL] [Abstract][Full Text] [Related]
19. Critical role of W60d in thrombin allostery. Guinto ER; Di Cera E Biophys Chem; 1997 Feb; 64(1-3):103-9. PubMed ID: 9127941 [TBL] [Abstract][Full Text] [Related]
20. The molecular basis of thrombin allostery revealed by a 1.8 A structure of the "slow" form. Huntington JA; Esmon CT Structure; 2003 Apr; 11(4):469-79. PubMed ID: 12679024 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]