BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

640 related articles for article (PubMed ID: 29474819)

  • 1. Direct evidence for high affinity blockade of Na
    Gonçalves TC; Boukaiba R; Molgó J; Amar M; Partiseti M; Servent D; Benoit E
    Neuropharmacology; 2018 May; 133():404-414. PubMed ID: 29474819
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthesis and biological characterization of synthetic analogs of Huwentoxin-IV (Mu-theraphotoxin-Hh2a), a neuronal tetrodotoxin-sensitive sodium channel inhibitor.
    Deng M; Luo X; Jiang L; Chen H; Wang J; He H; Liang S
    Toxicon; 2013 Sep; 71():57-65. PubMed ID: 23726857
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The structure, dynamics and selectivity profile of a NaV1.7 potency-optimised huwentoxin-IV variant.
    Rahnama S; Deuis JR; Cardoso FC; Ramanujam V; Lewis RJ; Rash LD; King GF; Vetter I; Mobli M
    PLoS One; 2017; 12(3):e0173551. PubMed ID: 28301520
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Pharmacological characterization of potent and selective NaV1.7 inhibitors engineered from Chilobrachys jingzhao tarantula venom peptide JzTx-V.
    Moyer BD; Murray JK; Ligutti J; Andrews K; Favreau P; Jordan JB; Lee JH; Liu D; Long J; Sham K; Shi L; Stöcklin R; Wu B; Yin R; Yu V; Zou A; Biswas K; Miranda LP
    PLoS One; 2018; 13(5):e0196791. PubMed ID: 29723257
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Spider peptide toxin HwTx-IV engineered to bind to lipid membranes has an increased inhibitory potency at human voltage-gated sodium channel hNa
    Agwa AJ; Lawrence N; Deplazes E; Cheneval O; Chen RM; Craik DJ; Schroeder CI; Henriques ST
    Biochim Biophys Acta Biomembr; 2017 May; 1859(5):835-844. PubMed ID: 28115115
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Native pyroglutamation of huwentoxin-IV: a post-translational modification that increases the trapping ability to the sodium channel.
    Rong M; Duan Z; Chen J; Li J; Xiao Y; Liang S
    PLoS One; 2013; 8(6):e65984. PubMed ID: 23826086
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Isoflurane inhibits the tetrodotoxin-resistant voltage-gated sodium channel Nav1.8.
    Herold KF; Nau C; Ouyang W; Hemmings HC
    Anesthesiology; 2009 Sep; 111(3):591-9. PubMed ID: 19672182
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The tarantula toxins ProTx-II and huwentoxin-IV differentially interact with human Nav1.7 voltage sensors to inhibit channel activation and inactivation.
    Xiao Y; Blumenthal K; Jackson JO; Liang S; Cummins TR
    Mol Pharmacol; 2010 Dec; 78(6):1124-34. PubMed ID: 20855463
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthetic Analogues of Huwentoxin-IV Spider Peptide With Altered Human Na
    Lopez L; Montnach J; Oliveira-Mendes B; Khakh K; Thomas B; Lin S; Caumes C; Wesolowski S; Nicolas S; Servent D; Cohen C; Béroud R; Benoit E; De Waard M
    Front Cell Dev Biol; 2021; 9():798588. PubMed ID: 34988086
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Manipulation of a spider peptide toxin alters its affinity for lipid bilayers and potency and selectivity for voltage-gated sodium channel subtype 1.7.
    Agwa AJ; Tran P; Mueller A; Tran HNT; Deuis JR; Israel MR; McMahon KL; Craik DJ; Vetter I; Schroeder CI
    J Biol Chem; 2020 Apr; 295(15):5067-5080. PubMed ID: 32139508
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Pharmacologic Characterization of AMG8379, a Potent and Selective Small Molecule Sulfonamide Antagonist of the Voltage-Gated Sodium Channel Na
    Kornecook TJ; Yin R; Altmann S; Be X; Berry V; Ilch CP; Jarosh M; Johnson D; Lee JH; Lehto SG; Ligutti J; Liu D; Luther J; Matson D; Ortuno D; Roberts J; Taborn K; Wang J; Weiss MM; Yu V; Zhu DXD; Fremeau RT; Moyer BD
    J Pharmacol Exp Ther; 2017 Jul; 362(1):146-160. PubMed ID: 28473457
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Tarantula huwentoxin-IV inhibits neuronal sodium channels by binding to receptor site 4 and trapping the domain ii voltage sensor in the closed configuration.
    Xiao Y; Bingham JP; Zhu W; Moczydlowski E; Liang S; Cummins TR
    J Biol Chem; 2008 Oct; 283(40):27300-13. PubMed ID: 18628201
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Voltage-gated sodium channel function and expression in injured and uninjured rat dorsal root ganglia neurons.
    Yin R; Liu D; Chhoa M; Li CM; Luo Y; Zhang M; Lehto SG; Immke DC; Moyer BD
    Int J Neurosci; 2016; 126(2):182-92. PubMed ID: 25562420
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Modulation of peripheral Na(+) channels and neuronal firing by n-butyl-p-aminobenzoate.
    Thériault O; Poulin H; Sculptoreanu A; de Groat WC; O'Leary ME; Chahine M
    Eur J Pharmacol; 2014 Mar; 727():158-66. PubMed ID: 24486399
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The effects of huwentoxin-I on the voltage-gated sodium channels of rat hippocampal and cockroach dorsal unpaired median neurons.
    Wang M; Rong M; Xiao Y; Liang S
    Peptides; 2012 Mar; 34(1):19-25. PubMed ID: 22094230
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Characterization of Endogenous Sodium Channels in the ND7-23 Neuroblastoma Cell Line: Implications for Use as a Heterologous Ion Channel Expression System Suitable for Automated Patch Clamp Screening.
    Rogers M; Zidar N; Kikelj D; Kirby RW
    Assay Drug Dev Technol; 2016 Mar; 14(2):109-30. PubMed ID: 26991361
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Tetrodotoxin-Sensitive Sodium Channels Mediate Action Potential Firing and Excitability in Menthol-Sensitive Vglut3-Lineage Sensory Neurons.
    Griffith TN; Docter TA; Lumpkin EA
    J Neurosci; 2019 Sep; 39(36):7086-7101. PubMed ID: 31300524
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Functional tetrodotoxin-resistant Na(+) channels are expressed presynaptically in rat dorsal root ganglia neurons.
    Medvedeva YV; Kim MS; Schnizler K; Usachev YM
    Neuroscience; 2009 Mar; 159(2):559-69. PubMed ID: 19162133
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Structure and function of hainantoxin-III, a selective antagonist of neuronal tetrodotoxin-sensitive voltage-gated sodium channels isolated from the Chinese bird spider Ornithoctonus hainana.
    Liu Z; Cai T; Zhu Q; Deng M; Li J; Zhou X; Zhang F; Li D; Li J; Liu Y; Hu W; Liang S
    J Biol Chem; 2013 Jul; 288(28):20392-403. PubMed ID: 23703613
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Evaluation of the Spider (
    Gonçalves TC; Lesport P; Kuylle S; Stura E; Ciolek J; Mourier G; Servent D; Bourinet E; Benoit E; Gilles N
    Toxins (Basel); 2019 Aug; 11(9):. PubMed ID: 31443554
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 32.