BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

348 related articles for article (PubMed ID: 29476642)

  • 1. The unfolded protein response in neurodegenerative disorders - therapeutic modulation of the PERK pathway.
    Hughes D; Mallucci GR
    FEBS J; 2019 Jan; 286(2):342-355. PubMed ID: 29476642
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Protein-rich foods, sea foods, and gut microbiota amplify immune responses in chronic diseases and cancers - Targeting PERK as a novel therapeutic strategy for chronic inflammatory diseases, neurodegenerative disorders, and cancer.
    Saaoud F; Lu Y; Xu K; Shao Y; Praticò D; Vazquez-Padron RI; Wang H; Yang X
    Pharmacol Ther; 2024 Mar; 255():108604. PubMed ID: 38360205
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The PERK-Dependent Molecular Mechanisms as a Novel Therapeutic Target for Neurodegenerative Diseases.
    Rozpędek-Kamińska W; Siwecka N; Wawrzynkiewicz A; Wojtczak R; Pytel D; Diehl JA; Majsterek I
    Int J Mol Sci; 2020 Mar; 21(6):. PubMed ID: 32204380
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Endoplasmic Reticulum Stress and Unfolded Protein Response in Neurodegenerative Diseases.
    Ghemrawi R; Khair M
    Int J Mol Sci; 2020 Aug; 21(17):. PubMed ID: 32854418
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mechanisms of disordered neurodegenerative function: concepts and facts about the different roles of the protein kinase RNA-like endoplasmic reticulum kinase (PERK).
    Taalab YM; Ibrahim N; Maher A; Hassan M; Mohamed W; Moustafa AA; Salama M; Johar D; Bernstein L
    Rev Neurosci; 2018 Jun; 29(4):387-415. PubMed ID: 29303785
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The Human Cytomegalovirus Endoplasmic Reticulum-Resident Glycoprotein UL148 Activates the Unfolded Protein Response.
    Siddiquey MNA; Zhang H; Nguyen CC; Domma AJ; Kamil JP
    J Virol; 2018 Oct; 92(20):. PubMed ID: 30045994
    [TBL] [Abstract][Full Text] [Related]  

  • 7. [Potential therapeutic application of PERK inhibitors].
    Basak J; Rozpędek W; Pytel D; Majsterek I
    Postepy Biochem; 2019 Jun; 65(2):118-127. PubMed ID: 31642650
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Protein kinase R(PKR)-like endoplasmic reticulum kinase (PERK) inhibitors: a patent review (2010-2015).
    Axten JM
    Expert Opin Ther Pat; 2017 Jan; 27(1):37-48. PubMed ID: 27646439
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Small molecule strategies to harness the unfolded protein response: where do we go from here?
    Grandjean JMD; Wiseman RL
    J Biol Chem; 2020 Nov; 295(46):15692-15711. PubMed ID: 32887796
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The eIF2 kinase PERK and the integrated stress response facilitate activation of ATF6 during endoplasmic reticulum stress.
    Teske BF; Wek SA; Bunpo P; Cundiff JK; McClintick JN; Anthony TG; Wek RC
    Mol Biol Cell; 2011 Nov; 22(22):4390-405. PubMed ID: 21917591
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The Role of PERK in Understanding Development of Neurodegenerative Diseases.
    Smedley GD; Walker KE; Yuan SH
    Int J Mol Sci; 2021 Jul; 22(15):. PubMed ID: 34360909
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The PERK/PKR-eIF2α Pathway Negatively Regulates Porcine Hemagglutinating Encephalomyelitis Virus Replication by Attenuating Global Protein Translation and Facilitating Stress Granule Formation.
    Shi J; Li Z; Xu R; Zhang J; Zhou Q; Gao R; Lu H; Lan Y; Zhao K; He H; Gao F; He W
    J Virol; 2022 Jan; 96(1):e0169521. PubMed ID: 34643429
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Imaging of single cell responses to ER stress indicates that the relative dynamics of IRE1/XBP1 and PERK/ATF4 signalling rather than a switch between signalling branches determine cell survival.
    Walter F; Schmid J; Düssmann H; Concannon CG; Prehn JH
    Cell Death Differ; 2015 Sep; 22(9):1502-16. PubMed ID: 25633195
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Modulation of the unfolded protein response impedes tumor cell adaptation to proteotoxic stress: a PERK for hepatocellular carcinoma therapy.
    Vandewynckel YP; Laukens D; Bogaerts E; Paridaens A; Van den Bussche A; Verhelst X; Van Steenkiste C; Descamps B; Vanhove C; Libbrecht L; De Rycke R; Lambrecht BN; Geerts A; Janssens S; Van Vlierberghe H
    Hepatol Int; 2015 Jan; 9(1):93-104. PubMed ID: 25598862
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The PERK Arm of the Unfolded Protein Response Negatively Regulates Transmissible Gastroenteritis Virus Replication by Suppressing Protein Translation and Promoting Type I Interferon Production.
    Xue M; Fu F; Ma Y; Zhang X; Li L; Feng L; Liu P
    J Virol; 2018 Aug; 92(15):. PubMed ID: 29769338
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The PERK pathway: beneficial or detrimental for neurodegenerative diseases and tumor growth and cancer.
    Talukdar G; Orr HT; Lei Z
    Hum Mol Genet; 2023 Aug; 32(16):2545-2557. PubMed ID: 37384418
    [TBL] [Abstract][Full Text] [Related]  

  • 17. PERK regulated miR-424(322)-503 cluster fine-tunes activation of IRE1 and ATF6 during Unfolded Protein Response.
    Gupta A; Hossain MM; Read DE; Hetz C; Samali A; Gupta S
    Sci Rep; 2015 Dec; 5():18304. PubMed ID: 26674075
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Fine tuning of the unfolded protein response by ISRIB improves neuronal survival in a model of amyotrophic lateral sclerosis.
    Bugallo R; Marlin E; Baltanás A; Toledo E; Ferrero R; Vinueza-Gavilanes R; Larrea L; Arrasate M; Aragón T
    Cell Death Dis; 2020 May; 11(5):397. PubMed ID: 32457286
    [TBL] [Abstract][Full Text] [Related]  

  • 19. PERK (Protein Kinase RNA-Like ER Kinase) Branch of the Unfolded Protein Response Confers Neuroprotection in Ischemic Stroke by Suppressing Protein Synthesis.
    Wang YC; Li X; Shen Y; Lyu J; Sheng H; Paschen W; Yang W
    Stroke; 2020 May; 51(5):1570-1577. PubMed ID: 32212900
    [TBL] [Abstract][Full Text] [Related]  

  • 20. [Involvement of unfolded protein responses in neurodegeneration].
    Kudo T
    Nihon Shinkei Seishin Yakurigaku Zasshi; 2003 Jun; 23(3):105-9. PubMed ID: 12884750
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 18.