BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

80 related articles for article (PubMed ID: 29480465)

  • 1. Production and Crystallization of Full-Length Human AMP-Activated Protein Kinase (α1β1γ1).
    Hubbard JA; Xiao B; Wilson JR
    Methods Mol Biol; 2018; 1732():1-14. PubMed ID: 29480465
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Visualizing AMPK Drug Binding Sites Through Crystallization of Full-Length Phosphorylated α2β1γ1 Heterotrimer.
    Langendorf CG; Oakhill JS; Kemp BE
    Methods Mol Biol; 2018; 1732():15-27. PubMed ID: 29480466
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Structures of AMP-activated protein kinase bound to novel pharmacological activators in phosphorylated, non-phosphorylated, and nucleotide-free states.
    Yan Y; Zhou XE; Novick SJ; Shaw SJ; Li Y; Brunzelle JS; Hitoshi Y; Griffin PR; Xu HE; Melcher K
    J Biol Chem; 2019 Jan; 294(3):953-967. PubMed ID: 30478170
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structural insights into the architecture and allostery of full-length AMP-activated protein kinase.
    Zhu L; Chen L; Zhou XM; Zhang YY; Zhang YJ; Zhao J; Ji SR; Wu JW; Wu Y
    Structure; 2011 Apr; 19(4):515-22. PubMed ID: 21481774
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Biophysical Interactions of Direct AMPK Activators.
    Kurumbail RG; West GM; Dharmarajan V; Borzilleri KA; Withka JM; Ward J; Reyes AR; Rajamohan F; Griffin PR; Calabrese MF
    Methods Mol Biol; 2018; 1732():29-55. PubMed ID: 29480467
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Structural basis of AMPK regulation by adenine nucleotides and glycogen.
    Li X; Wang L; Zhou XE; Ke J; de Waal PW; Gu X; Tan MH; Wang D; Wu D; Xu HE; Melcher K
    Cell Res; 2015 Jan; 25(1):50-66. PubMed ID: 25412657
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Transient Expression of AMPK Heterotrimer Complexes in Mammalian Cells.
    Oakhill JS; Scott JW; Dite TA
    Methods Mol Biol; 2018; 1732():159-169. PubMed ID: 29480474
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Structural basis of AMPK regulation by small molecule activators.
    Xiao B; Sanders MJ; Carmena D; Bright NJ; Haire LF; Underwood E; Patel BR; Heath RB; Walker PA; Hallen S; Giordanetto F; Martin SR; Carling D; Gamblin SJ
    Nat Commun; 2013; 4():3017. PubMed ID: 24352254
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Mammalian AMP-activated protein kinase: functional, heterotrimeric complexes by co-expression of subunits in Escherichia coli.
    Neumann D; Woods A; Carling D; Wallimann T; Schlattner U
    Protein Expr Purif; 2003 Aug; 30(2):230-7. PubMed ID: 12880772
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Architectural plasticity of AMPK revealed by electron microscopy and X-ray crystallography.
    Ouyang Y; Zhu L; Li Y; Guo M; Liu Y; Cheng J; Zhao J; Wu Y
    Sci Rep; 2016 Apr; 6():24191. PubMed ID: 27063142
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Crystal structures of the adenylate sensor from fission yeast AMP-activated protein kinase.
    Townley R; Shapiro L
    Science; 2007 Mar; 315(5819):1726-9. PubMed ID: 17289942
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Purification and characterization of truncated human AMPK alpha 2 beta 2 gamma 3 heterotrimer from baculovirus-infected insect cells.
    Ramanathan L; Sheth PR; Ogas P; Xiao L; Le HV
    Protein Expr Purif; 2010 Mar; 70(1):13-22. PubMed ID: 19836452
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Comprehensive Characterization of AMP-Activated Protein Kinase Catalytic Domain by Top-Down Mass Spectrometry.
    Yu D; Peng Y; Ayaz-Guner S; Gregorich ZR; Ge Y
    J Am Soc Mass Spectrom; 2016 Feb; 27(2):220-32. PubMed ID: 26489410
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Structural basis for compound C inhibition of the human AMP-activated protein kinase α2 subunit kinase domain.
    Handa N; Takagi T; Saijo S; Kishishita S; Takaya D; Toyama M; Terada T; Shirouzu M; Suzuki A; Lee S; Yamauchi T; Okada-Iwabu M; Iwabu M; Kadowaki T; Minokoshi Y; Yokoyama S
    Acta Crystallogr D Biol Crystallogr; 2011 May; 67(Pt 5):480-7. PubMed ID: 21543851
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Crystallization of the glycogen-binding domain of the AMP-activated protein kinase beta subunit and preliminary X-ray analysis.
    Polekhina G; Feil SC; Gupta A; O'Donnell P; Stapleton D; Parker MW
    Acta Crystallogr Sect F Struct Biol Cryst Commun; 2005 Jan; 61(Pt 1):39-42. PubMed ID: 16508085
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A conserved mechanism of autoinhibition for the AMPK kinase domain: ATP-binding site and catalytic loop refolding as a means of regulation.
    Littler DR; Walker JR; Davis T; Wybenga-Groot LE; Finerty PJ; Newman E; Mackenzie F; Dhe-Paganon S
    Acta Crystallogr Sect F Struct Biol Cryst Commun; 2010 Feb; 66(Pt 2):143-51. PubMed ID: 20124709
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Structure and Regulation of AMPK.
    Kurumbail RG; Calabrese MF
    Exp Suppl; 2016; 107():3-22. PubMed ID: 27812974
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Conformational heterogeneity of the allosteric drug and metabolite (ADaM) site in AMP-activated protein kinase (AMPK).
    Gu X; Bridges MD; Yan Y; de Waal PW; Zhou XE; Suino-Powell KM; Xu HE; Hubbell WL; Melcher K
    J Biol Chem; 2018 Nov; 293(44):16994-17007. PubMed ID: 30206123
    [TBL] [Abstract][Full Text] [Related]  

  • 19. AMPK is a direct adenylate charge-regulated protein kinase.
    Oakhill JS; Steel R; Chen ZP; Scott JW; Ling N; Tam S; Kemp BE
    Science; 2011 Jun; 332(6036):1433-5. PubMed ID: 21680840
    [TBL] [Abstract][Full Text] [Related]  

  • 20. AMPK-Mediated Regulation of Lipid Metabolism by Phosphorylation.
    Wang Q; Liu S; Zhai A; Zhang B; Tian G
    Biol Pharm Bull; 2018 Jul; 41(7):985-993. PubMed ID: 29709897
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 4.