BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

358 related articles for article (PubMed ID: 29481745)

  • 21. Natural Product Splicing Inhibitors: A New Class of Antibody-Drug Conjugate (ADC) Payloads.
    Puthenveetil S; Loganzo F; He H; Dirico K; Green M; Teske J; Musto S; Clark T; Rago B; Koehn F; Veneziale R; Falahaptisheh H; Han X; Barletta F; Lucas J; Subramanyam C; O'Donnell CJ; Tumey LN; Sapra P; Gerber HP; Ma D; Graziani EI
    Bioconjug Chem; 2016 Aug; 27(8):1880-8. PubMed ID: 27412791
    [TBL] [Abstract][Full Text] [Related]  

  • 22. The Recent Developments of ADCs with the Tubulysins as the Payloads.
    Xiangrong X; Yao L; Yao A
    Mini Rev Med Chem; 2023; 23(18):1797-1805. PubMed ID: 36825713
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Chimeric Small Antibody Fragments as Strategy to Deliver Therapeutic Payloads.
    Aguiar S; Dias J; Manuel AM; Russo R; Gois PMP; da Silva FA; Goncalves J
    Adv Protein Chem Struct Biol; 2018; 112():143-182. PubMed ID: 29680236
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Antibody drug conjugates: design and selection of linker, payload and conjugation chemistry.
    McCombs JR; Owen SC
    AAPS J; 2015 Mar; 17(2):339-51. PubMed ID: 25604608
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Impact of drug conjugation on pharmacokinetics and tissue distribution of anti-STEAP1 antibody-drug conjugates in rats.
    Boswell CA; Mundo EE; Zhang C; Bumbaca D; Valle NR; Kozak KR; Fourie A; Chuh J; Koppada N; Saad O; Gill H; Shen BQ; Rubinfeld B; Tibbitts J; Kaur S; Theil FP; Fielder PJ; Khawli LA; Lin K
    Bioconjug Chem; 2011 Oct; 22(10):1994-2004. PubMed ID: 21913715
    [TBL] [Abstract][Full Text] [Related]  

  • 26. UPLC-based assay to assess the hydrophobicity of Antibody-Drug Conjugate (ADC) payloads.
    Pysz I; Jackson PJM; Barlow DJ; Rahman KM; Thurston DE
    J Chromatogr B Analyt Technol Biomed Life Sci; 2020 Jun; 1146():122075. PubMed ID: 32361467
    [TBL] [Abstract][Full Text] [Related]  

  • 27. A simple LC/MRM-MS-based method to quantify free linker-payload in antibody-drug conjugate preparations.
    Zmolek W; BaƱas S; Barfield RM; Rabuka D; Drake PM
    J Chromatogr B Analyt Technol Biomed Life Sci; 2016 Oct; 1032():144-148. PubMed ID: 27311685
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Optimizing Lysosomal Activation of Antibody-Drug Conjugates (ADCs) by Incorporation of Novel Cleavable Dipeptide Linkers.
    Salomon PL; Reid EE; Archer KE; Harris L; Maloney EK; Wilhelm AJ; Miller ML; Chari RVJ; Keating TA; Singh R
    Mol Pharm; 2019 Dec; 16(12):4817-4825. PubMed ID: 31609629
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Site-Specific Quantitation of Drug Conjugations on Antibody-Drug Conjugates (ADCs) Using a Protease-Assisted Drug Deconjugation and Linker-like Labeling (PADDLL) Method.
    Yang X; Seol H; Lin W; Xu X; Shen B; Qiu H; Li N
    Anal Chem; 2021 Jul; 93(27):9549-9558. PubMed ID: 34196532
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Rational design, biophysical and biological characterization of site-specific antibody-tubulysin conjugates with improved stability, efficacy and pharmacokinetics.
    Thompson P; Fleming R; Bezabeh B; Huang F; Mao S; Chen C; Harper J; Zhong H; Gao X; Yu XQ; Hinrichs MJ; Reed M; Kamal A; Strout P; Cho S; Woods R; Hollingsworth RE; Dixit R; Wu H; Gao C; Dimasi N
    J Control Release; 2016 Aug; 236():100-16. PubMed ID: 27327768
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Antibody drug conjugates beyond cytotoxic payloads.
    Hobson AD
    Prog Med Chem; 2023; 62():1-59. PubMed ID: 37981349
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Quantitative Conjugated Payload Measurement Using Enzymatic Release of Antibody-Drug Conjugate with Cleavable Linker.
    Rago B; Tumey LN; Wei C; Barletta F; Clark T; Hansel S; Han X
    Bioconjug Chem; 2017 Feb; 28(2):620-626. PubMed ID: 28140559
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Design and Validation of Linkers for Site-Specific Preparation of Antibody-Drug Conjugates Carrying Multiple Drug Copies Per Cysteine Conjugation Site.
    Kumar A; Mao S; Dimasi N; Gao C
    Int J Mol Sci; 2020 Sep; 21(18):. PubMed ID: 32961794
    [TBL] [Abstract][Full Text] [Related]  

  • 34. The Analysis of Key Factors Related to ADCs Structural Design.
    Tang H; Liu Y; Yu Z; Sun M; Lin L; Liu W; Han Q; Wei M; Jin Y
    Front Pharmacol; 2019; 10():373. PubMed ID: 31068807
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Carfilzomib Is Not an Appropriate Payload of Antibody-Drug Conjugates Due to Rapid Inactivation by Lysosomal Enzymes.
    Ma Y; Dela Cruz-Chuh J; Khojasteh SC; Dragovich PS; Pillow TH; Zhang D
    Drug Metab Dispos; 2019 Aug; 47(8):884-889. PubMed ID: 31072822
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Total Synthesis in Search of Potent Antibody-Drug Conjugate Payloads. From the Fundamentals to the Translational.
    Nicolaou KC; Rigol S
    Acc Chem Res; 2019 Jan; 52(1):127-139. PubMed ID: 30575399
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Physical and Chemical Stability of Antibody Drug Conjugates: Current Status.
    Ross PL; Wolfe JL
    J Pharm Sci; 2016 Feb; 105(2):391-397. PubMed ID: 26869406
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Tuning the Diels-Alder Reaction for Bioconjugation to Maleimide Drug-Linkers.
    St Amant AH; Lemen D; Florinas S; Mao S; Fazenbaker C; Zhong H; Wu H; Gao C; Christie RJ; Read de Alaniz J
    Bioconjug Chem; 2018 Jul; 29(7):2406-2414. PubMed ID: 29932647
    [TBL] [Abstract][Full Text] [Related]  

  • 39. High-Throughput Cysteine Scanning To Identify Stable Antibody Conjugation Sites for Maleimide- and Disulfide-Based Linkers.
    Ohri R; Bhakta S; Fourie-O'Donohue A; Dela Cruz-Chuh J; Tsai SP; Cook R; Wei B; Ng C; Wong AW; Bos AB; Farahi F; Bhakta J; Pillow TH; Raab H; Vandlen R; Polakis P; Liu Y; Erickson H; Junutula JR; Kozak KR
    Bioconjug Chem; 2018 Feb; 29(2):473-485. PubMed ID: 29425028
    [TBL] [Abstract][Full Text] [Related]  

  • 40. In vivo testing of drug-linker stability.
    Abecassis PY; Amara C
    Methods Mol Biol; 2013; 1045():101-16. PubMed ID: 23913143
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 18.