BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

351 related articles for article (PubMed ID: 29483142)

  • 1. STAT5A/B Blockade Sensitizes Prostate Cancer to Radiation through Inhibition of RAD51 and DNA Repair.
    Maranto C; Udhane V; Hoang DT; Gu L; Alexeev V; Malas K; Cardenas K; Brody JR; Rodeck U; Bergom C; Iczkowski KA; Jacobsohn K; See W; Schmitt SM; Nevalainen MT
    Clin Cancer Res; 2018 Apr; 24(8):1917-1931. PubMed ID: 29483142
    [No Abstract]   [Full Text] [Related]  

  • 2. Pharmacologic inhibition of Jak2-Stat5 signaling By Jak2 inhibitor AZD1480 potently suppresses growth of both primary and castrate-resistant prostate cancer.
    Gu L; Liao Z; Hoang DT; Dagvadorj A; Gupta S; Blackmon S; Ellsworth E; Talati P; Leiby B; Zinda M; Lallas CD; Trabulsi EJ; McCue P; Gomella L; Huszar D; Nevalainen MT
    Clin Cancer Res; 2013 Oct; 19(20):5658-74. PubMed ID: 23942095
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Transcription factor signal transducer and activator of transcription 5 promotes growth of human prostate cancer cells in vivo.
    Dagvadorj A; Kirken RA; Leiby B; Karras J; Nevalainen MT
    Clin Cancer Res; 2008 Mar; 14(5):1317-24. PubMed ID: 18316550
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structure-Based Screen Identifies a Potent Small Molecule Inhibitor of Stat5a/b with Therapeutic Potential for Prostate Cancer and Chronic Myeloid Leukemia.
    Liao Z; Gu L; Vergalli J; Mariani SA; De Dominici M; Lokareddy RK; Dagvadorj A; Purushottamachar P; McCue PA; Trabulsi E; Lallas CD; Gupta S; Ellsworth E; Blackmon S; Ertel A; Fortina P; Leiby B; Xia G; Rui H; Hoang DT; Gomella LG; Cingolani G; Njar V; Pattabiraman N; Calabretta B; Nevalainen MT
    Mol Cancer Ther; 2015 Aug; 14(8):1777-93. PubMed ID: 26026053
    [TBL] [Abstract][Full Text] [Related]  

  • 5. MDM2 Inhibition Sensitizes Prostate Cancer Cells to Androgen Ablation and Radiotherapy in a p53-Dependent Manner.
    Feng FY; Zhang Y; Kothari V; Evans JR; Jackson WC; Chen W; Johnson SB; Luczak C; Wang S; Hamstra DA
    Neoplasia; 2016 Apr; 18(4):213-22. PubMed ID: 27108384
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Inhibition of both EGFR and IGF1R sensitized prostate cancer cells to radiation by synergistic suppression of DNA homologous recombination repair.
    Wang Y; Yuan JL; Zhang YT; Ma JJ; Xu P; Shi CH; Zhang W; Li YM; Fu Q; Zhu GF; Xue W; Lei YH; Gao JY; Wang JY; Shao C; Yi CG; Wang H
    PLoS One; 2013; 8(8):e68784. PubMed ID: 23950876
    [TBL] [Abstract][Full Text] [Related]  

  • 7. RPA1 downregulation enhances nasopharyngeal cancer radiosensitivity via blocking RAD51 to the DNA damage site.
    Zhang Z; Huo H; Liao K; Wang Z; Gong Z; Li Y; Liu C; Hu G
    Exp Cell Res; 2018 Oct; 371(2):330-341. PubMed ID: 30144445
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Jak2-Stat5a/b Signaling Induces Epithelial-to-Mesenchymal Transition and Stem-Like Cell Properties in Prostate Cancer.
    Talati PG; Gu L; Ellsworth EM; Girondo MA; Trerotola M; Hoang DT; Leiby B; Dagvadorj A; McCue PA; Lallas CD; Trabulsi EJ; Gomella L; Aplin AE; Languino L; Fatatis A; Rui H; Nevalainen MT
    Am J Pathol; 2015 Sep; 185(9):2505-22. PubMed ID: 26362718
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Suppression of homologous recombination sensitizes human tumor cells to IGF-1R inhibition.
    Lodhia KA; Gao S; Aleksic T; Esashi F; Macaulay VM
    Int J Cancer; 2015 Jun; 136(12):2961-6. PubMed ID: 25388513
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Defective DNA strand break repair after DNA damage in prostate cancer cells: implications for genetic instability and prostate cancer progression.
    Fan R; Kumaravel TS; Jalali F; Marrano P; Squire JA; Bristow RG
    Cancer Res; 2004 Dec; 64(23):8526-33. PubMed ID: 15574758
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Cyclin D1 silencing suppresses tumorigenicity, impairs DNA double strand break repair and thus radiosensitizes androgen-independent prostate cancer cells to DNA damage.
    Marampon F; Gravina G; Ju X; Vetuschi A; Sferra R; Casimiro M; Pompili S; Festuccia C; Colapietro A; Gaudio E; Di Cesare E; Tombolini V; Pestell RG
    Oncotarget; 2016 Feb; 7(5):5383-400. PubMed ID: 26689991
    [TBL] [Abstract][Full Text] [Related]  

  • 12. N-terminal truncation of Stat5a/b circumvents PIAS3-mediated transcriptional inhibition of Stat5 in prostate cancer cells.
    Dagvadorj A; Tan SH; Liao Z; Xie J; Nurmi M; Alanen K; Rui H; Mirtti T; Nevalainen MT
    Int J Biochem Cell Biol; 2010 Dec; 42(12):2037-46. PubMed ID: 20854925
    [TBL] [Abstract][Full Text] [Related]  

  • 13. RNA-seq profiling of a radiation resistant and radiation sensitive prostate cancer cell line highlights opposing regulation of DNA repair and targets for radiosensitization.
    Young A; Berry R; Holloway AF; Blackburn NB; Dickinson JL; Skala M; Phillips JL; Brettingham-Moore KH
    BMC Cancer; 2014 Nov; 14():808. PubMed ID: 25369795
    [TBL] [Abstract][Full Text] [Related]  

  • 14. TAS-116, a Novel Hsp90 Inhibitor, Selectively Enhances Radiosensitivity of Human Cancer Cells to X-rays and Carbon Ion Radiation.
    Lee Y; Sunada S; Hirakawa H; Fujimori A; Nickoloff JA; Okayasu R
    Mol Cancer Ther; 2017 Jan; 16(1):16-24. PubMed ID: 28062703
    [TBL] [Abstract][Full Text] [Related]  

  • 15. HDAC Inhibition Induces MicroRNA-182, which Targets RAD51 and Impairs HR Repair to Sensitize Cells to Sapacitabine in Acute Myelogenous Leukemia.
    Lai TH; Ewald B; Zecevic A; Liu C; Sulda M; Papaioannou D; Garzon R; Blachly JS; Plunkett W; Sampath D
    Clin Cancer Res; 2016 Jul; 22(14):3537-49. PubMed ID: 26858310
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Inhibition of FGFR2-Signaling Attenuates a Homology-Mediated DNA Repair in GIST and Sensitizes Them to DNA-Topoisomerase II Inhibitors.
    Sergei B; Pavel D; Aigul G; Firyuza B; Ilmira N; Ilshat M; Aida A; Refat K; Natalia A; Elena S; Vera G
    Int J Mol Sci; 2020 Jan; 21(1):. PubMed ID: 31948066
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Androgen Deprivation Followed by Acute Androgen Stimulation Selectively Sensitizes AR-Positive Prostate Cancer Cells to Ionizing Radiation.
    Hedayati M; Haffner MC; Coulter JB; Raval RR; Zhang Y; Zhou H; Mian O; Knight EJ; Razavi N; Dalrymple S; Isaacs JT; Santos A; Hales R; Nelson WG; Yegnasubramanian S; DeWeese TL
    Clin Cancer Res; 2016 Jul; 22(13):3310-3319. PubMed ID: 26831716
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Integrin αVβ3 silencing sensitizes malignant glioma cells to temozolomide by suppression of homologous recombination repair.
    Christmann M; Diesler K; Majhen D; Steigerwald C; Berte N; Freund H; Stojanović N; Kaina B; Osmak M; Ambriović-Ristov A; Tomicic MT
    Oncotarget; 2017 Apr; 8(17):27754-27771. PubMed ID: 27487141
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Adamantanyl-histone deacetylase inhibitor H6CAHA exhibits favorable pharmacokinetics and augments prostate cancer radiation sensitivity.
    Konsoula Z; Cao H; Velena A; Jung M
    Int J Radiat Oncol Biol Phys; 2011 Apr; 79(5):1541-8. PubMed ID: 21277099
    [TBL] [Abstract][Full Text] [Related]  

  • 20. BMS-345541 sensitizes MCF-7 breast cancer cells to ionizing radiation by selective inhibition of homologous recombinational repair of DNA double-strand breaks.
    Wu L; Shao L; Li M; Zheng J; Wang J; Feng W; Chang J; Wang Y; Hauer-Jensen M; Zhou D
    Radiat Res; 2013 Feb; 179(2):160-70. PubMed ID: 23259762
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 18.