These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
4. Metabotype analysis of Mthfd1l-null mouse embryos using desorption electrospray ionization mass spectrometry imaging. Vaughn A; DeHoog RJ; Eberlin LS; Appling DR Anal Bioanal Chem; 2021 May; 413(13):3573-3582. PubMed ID: 33829277 [TBL] [Abstract][Full Text] [Related]
5. Mitochondrial C1-tetrahydrofolate synthase (MTHFD1L) supports the flow of mitochondrial one-carbon units into the methyl cycle in embryos. Pike ST; Rajendra R; Artzt K; Appling DR J Biol Chem; 2010 Feb; 285(7):4612-20. PubMed ID: 19948730 [TBL] [Abstract][Full Text] [Related]
6. Maternal Mthfd1 disruption impairs fetal growth but does not cause neural tube defects in mice. Beaudin AE; Perry CA; Stabler SP; Allen RH; Stover PJ Am J Clin Nutr; 2012 Apr; 95(4):882-91. PubMed ID: 22378735 [TBL] [Abstract][Full Text] [Related]
7. An NTD-associated polymorphism in the 3' UTR of MTHFD1L can affect disease risk by altering miRNA binding. Minguzzi S; Selcuklu SD; Spillane C; Parle-McDermott A Hum Mutat; 2014 Jan; 35(1):96-104. PubMed ID: 24123340 [TBL] [Abstract][Full Text] [Related]
8. Mitochondrial one-carbon metabolism and neural tube defects. Momb J; Appling DR Birth Defects Res A Clin Mol Teratol; 2014 Aug; 100(8):576-83. PubMed ID: 24985542 [TBL] [Abstract][Full Text] [Related]
9. Formate Supplementation May Prevent Some Neural Tube Defects that Prove Resistant to Folic Acid: Supplementation with formate rescued normal neural tube closure in more than three quarters of the embryos of novel folic acid-resistant neural tube defect mouse models. Am J Med Genet A; 2018 Aug; 176(8):1697-1698. PubMed ID: 30136438 [No Abstract] [Full Text] [Related]
10. A novel mouse model for genetic variation in 10-formyltetrahydrofolate synthetase exhibits disturbed purine synthesis with impacts on pregnancy and embryonic development. Christensen KE; Deng L; Leung KY; Arning E; Bottiglieri T; Malysheva OV; Caudill MA; Krupenko NI; Greene ND; Jerome-Majewska L; MacKenzie RE; Rozen R Hum Mol Genet; 2013 Sep; 22(18):3705-19. PubMed ID: 23704330 [TBL] [Abstract][Full Text] [Related]
11. Folate cycle enzyme MTHFD1L confers metabolic advantages in hepatocellular carcinoma. Lee D; Xu IM; Chiu DK; Lai RK; Tse AP; Lan Li L; Law CT; Tsang FH; Wei LL; Chan CY; Wong CM; Ng IO; Wong CC J Clin Invest; 2017 May; 127(5):1856-1872. PubMed ID: 28394261 [TBL] [Abstract][Full Text] [Related]
12. MTHFD1L as a folate cycle enzyme correlates with prognostic outcome and its knockdown impairs cell invasive behaviors in osteosarcoma via mediating the AKT/mTOR pathway. Wang L; Yang Y; Wang XM; Wang CQ; Zhang YM; Li BL J Recept Signal Transduct Res; 2020 Dec; 40(6):584-590. PubMed ID: 32456526 [TBL] [Abstract][Full Text] [Related]
13. Moderate folic acid supplementation and MTHFD1-synthetase deficiency in mice, a model for the R653Q variant, result in embryonic defects and abnormal placental development. Christensen KE; Hou W; Bahous RH; Deng L; Malysheva OV; Arning E; Bottiglieri T; Caudill MA; Jerome-Majewska LA; Rozen R Am J Clin Nutr; 2016 Nov; 104(5):1459-1469. PubMed ID: 27707701 [TBL] [Abstract][Full Text] [Related]
14. Mitochondrial MTHFD2L is a dual redox cofactor-specific methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase expressed in both adult and embryonic tissues. Shin M; Bryant JD; Momb J; Appling DR J Biol Chem; 2014 May; 289(22):15507-17. PubMed ID: 24733394 [TBL] [Abstract][Full Text] [Related]
15. Melatonin modulates metabolic remodeling in HNSCC by suppressing MTHFD1L-formate axis. Cui L; Zhao X; Jin Z; Wang H; Yang SF; Hu S J Pineal Res; 2021 Dec; 71(4):e12767. PubMed ID: 34533844 [TBL] [Abstract][Full Text] [Related]
17. Mitochondrial NAD-dependent methylenetetrahydrofolate dehydrogenase-methenyltetrahydrofolate cyclohydrolase is essential for embryonic development. Di Pietro E; Sirois J; Tremblay ML; MacKenzie RE Mol Cell Biol; 2002 Jun; 22(12):4158-66. PubMed ID: 12024029 [TBL] [Abstract][Full Text] [Related]
18. Association of main folate metabolic pathway gene polymorphisms with neural tube defects in Han population of Northern China. Fang Y; Zhang R; Zhi X; Zhao L; Cao L; Wang Y; Cai C Childs Nerv Syst; 2018 Apr; 34(4):725-729. PubMed ID: 29392422 [TBL] [Abstract][Full Text] [Related]
19. Distinct effects of folate pathway genes MTHFR and MTHFD1L on ruminative response style: a potential risk mechanism for depression. Eszlari N; Kovacs D; Petschner P; Pap D; Gonda X; Elliott R; Anderson IM; Deakin JF; Bagdy G; Juhasz G Transl Psychiatry; 2016 Mar; 6(3):e745. PubMed ID: 26926881 [TBL] [Abstract][Full Text] [Related]
20. Integrated bioinformatics analysis identified MTHFD1L as a potential biomarker and correlated with immune infiltrates in hepatocellular carcinoma. Chen J; Yang J; Xu Q; Wang Z; Wu J; Pan L; Huang K; Wang C Biosci Rep; 2021 Feb; 41(2):. PubMed ID: 33605411 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]