307 related articles for article (PubMed ID: 29485001)
1. Design and Synthesis of 3,4-diarylpyrrole Analogues as Potent Topoisomerase Inhibitors.
Chen W; Feng Z; He X; Zhao Q; Liang Q
Med Chem; 2018; 14(5):485-494. PubMed ID: 29485001
[TBL] [Abstract][Full Text] [Related]
2. Design and Synthesis of Arylnaphthalene Lignan Lactone Derivatives as Potent Topoisomerase Inhibitors.
Chen W; Feng Z; Hu D; Meng J
Med Chem; 2021; 17(8):856-865. PubMed ID: 32520691
[TBL] [Abstract][Full Text] [Related]
3. Topoisomerase IIα inhibitory and antiproliferative activity of dihydroxylated 2,6-diphenyl-4-fluorophenylpyridines: Design, synthesis, and structure-activity relationships.
Kunwar S; Hwang SY; Katila P; Man Kadayat T; Jung AR; Kwon Y; Lee ES
Bioorg Med Chem Lett; 2022 Mar; 60():128606. PubMed ID: 35123005
[TBL] [Abstract][Full Text] [Related]
4. Novel nalidixic acid derivatives targeting topoisomerase II enzyme; Design, synthesis, anticancer activity and effect on cell cycle profile.
Khalil OM; Gedawy EM; El-Malah AA; Adly ME
Bioorg Chem; 2019 Mar; 83():262-276. PubMed ID: 30391699
[TBL] [Abstract][Full Text] [Related]
5. 4-Flourophenyl-substituted 5H-indeno[1,2-b]pyridinols with enhanced topoisomerase IIα inhibitory activity: Synthesis, biological evaluation, and structure-activity relationships.
Kunwar S; Hwang SY; Katila P; Seo M; Man Kadayat T; Kwon Y; Lee ES
Bioorg Chem; 2021 Nov; 116():105349. PubMed ID: 34536927
[TBL] [Abstract][Full Text] [Related]
6. CS1 is a novel topoisomerase IIα inhibitor with favorable drug resistance profiles.
Shen Y; Chen W; Zhao B; Hao H; Li Z; Lu C; Shen Y
Biochem Biophys Res Commun; 2014 Oct; 453(3):302-8. PubMed ID: 25242524
[TBL] [Abstract][Full Text] [Related]
7. Synthesis and antiproliferative activity of 9-benzylamino-6-chloro-2-methoxy-acridine derivatives as potent DNA-binding ligands and topoisomerase II inhibitors.
Zhang W; Zhang B; Zhang W; Yang T; Wang N; Gao C; Tan C; Liu H; Jiang Y
Eur J Med Chem; 2016 Jun; 116():59-70. PubMed ID: 27060757
[TBL] [Abstract][Full Text] [Related]
8. Synthesis, Biological Evaluation and Molecular Docking Study of Cyclic Diarylheptanoids as Potential Anticancer Therapeutics.
Lu Y; Yin W; Alam MS; Kadi AA; Jahng Y; Kwon Y; Rahman AFMM
Anticancer Agents Med Chem; 2020; 20(4):464-475. PubMed ID: 31763968
[TBL] [Abstract][Full Text] [Related]
9. Structure-guided optimization of 4,6-substituted-1,3,5-triazin-2(1H)-ones as catalytic inhibitors of human DNA topoisomerase IIα.
Bergant K; Janežič M; Valjavec K; Sosič I; Pajk S; Štampar M; Žegura B; Gobec S; Filipič M; Perdih A
Eur J Med Chem; 2019 Aug; 175():330-348. PubMed ID: 31096154
[TBL] [Abstract][Full Text] [Related]
10. Design, synthesis, biological evaluation, structure-activity relationship study, and mode of action of 2-phenol-4,6-dichlorophenyl-pyridines.
Shrestha A; Park S; Shin S; Man Kadayat T; Bist G; Katila P; Kwon Y; Lee ES
Bioorg Chem; 2018 Sep; 79():1-18. PubMed ID: 29715635
[TBL] [Abstract][Full Text] [Related]
11. 4β-amidotriazole linked podophyllotoxin congeners: DNA topoisomerase-IIα inhibition and potential anticancer agents for prostate cancer.
Reddy VG; Bonam SR; Reddy TS; Akunuri R; Naidu VGM; Nayak VL; Bhargava SK; Kumar HMS; Srihari P; Kamal A
Eur J Med Chem; 2018 Jan; 144():595-611. PubMed ID: 29289884
[TBL] [Abstract][Full Text] [Related]
12. Design, synthesis, molecular modeling and anti-proliferative evaluation of novel quinoxaline derivatives as potential DNA intercalators and topoisomerase II inhibitors.
Ibrahim MK; Taghour MS; Metwaly AM; Belal A; Mehany ABM; Elhendawy MA; Radwan MM; Yassin AM; El-Deeb NM; Hafez EE; ElSohly MA; Eissa IH
Eur J Med Chem; 2018 Jul; 155():117-134. PubMed ID: 29885574
[TBL] [Abstract][Full Text] [Related]
13. A rational design strategy of the novel topoisomerase II inhibitors for the synthesis of the 4-O-(2-pyrazinecarboxylic)-4'-demethylepipodophyllotoxin with antitumor activity by diminishing the relaxation reaction of topoisomerase II-DNA decatenation.
Zhao W; Chen L; Li HM; Wang DJ; Li DS; Chen T; Yuan ZP; Tang YJ
Bioorg Med Chem; 2014 Jun; 22(11):2998-3007. PubMed ID: 24775914
[TBL] [Abstract][Full Text] [Related]
14. Novel 2-aryl-4-(4'-hydroxyphenyl)-5H-indeno[1,2-b]pyridines as potent DNA non-intercalative topoisomerase catalytic inhibitors.
Park S; Kadayat TM; Jun KY; Thapa Magar TB; Bist G; Shrestha A; Lee ES; Kwon Y
Eur J Med Chem; 2017 Jan; 125():14-28. PubMed ID: 27643560
[TBL] [Abstract][Full Text] [Related]
15. Novel ciprofloxacin hybrids using biology oriented drug synthesis (BIODS) approach: Anticancer activity, effects on cell cycle profile, caspase-3 mediated apoptosis, topoisomerase II inhibition, and antibacterial activity.
Kassab AE; Gedawy EM
Eur J Med Chem; 2018 Apr; 150():403-418. PubMed ID: 29547830
[TBL] [Abstract][Full Text] [Related]
16. Design, synthesis and biological evaluation of novel perimidine o-quinone derivatives as non-intercalative topoisomerase II catalytic inhibitors.
Zhou DC; Lu YT; Mai YW; Zhang C; Xia J; Yao PF; Wang HG; Huang SL; Huang ZS
Bioorg Chem; 2019 Oct; 91():103131. PubMed ID: 31377387
[TBL] [Abstract][Full Text] [Related]
17. Synthesis and structure-activity relationships of hydroxylated and halogenated 2,4-diaryl benzofuro[3,2-b]pyridin-7-ols as selective topoisomerase IIα inhibitors.
Thapa Magar TB; Hee Seo S; Shrestha A; Kim JA; Kunwar S; Bist G; Kwon Y; Lee ES
Bioorg Chem; 2021 Jun; 111():104884. PubMed ID: 33872925
[TBL] [Abstract][Full Text] [Related]
18. Synthesis, computational quantum chemical study, in silico ADMET and molecular docking analysis, in vitro biological evaluation of a novel sulfur heterocyclic thiophene derivative containing 1,2,3-triazole and pyridine moieties as a potential human topoisomerase IIα inhibiting anticancer agent.
Murugavel S; Ravikumar C; Jaabil G; Alagusundaram P
Comput Biol Chem; 2019 Apr; 79():73-82. PubMed ID: 30731361
[TBL] [Abstract][Full Text] [Related]
19. Inhibition of topoisomerase IIα and induction of DNA damage in cholangiocarcinoma cells by altholactone and its halogenated benzoate derivatives.
Kitdumrongthum S; Reabroi S; Suksen K; Tuchinda P; Munyoo B; Mahalapbutr P; Rungrotmongkol T; Ounjai P; Chairoungdua A
Biomed Pharmacother; 2020 Jul; 127():110149. PubMed ID: 32344256
[TBL] [Abstract][Full Text] [Related]
20. Synthesis and Mechanism Studies of 1,3-Benzoazolyl Substituted Pyrrolo[2,3-b]pyrazine Derivatives as Nonintercalative Topoisomerase II Catalytic Inhibitors.
Li PH; Zeng P; Chen SB; Yao PF; Mai YW; Tan JH; Ou TM; Huang SL; Li D; Gu LQ; Huang ZS
J Med Chem; 2016 Jan; 59(1):238-52. PubMed ID: 26649766
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
