360 related articles for article (PubMed ID: 29487110)
1. Farnesoid X Receptor Agonists Obeticholic Acid and Chenodeoxycholic Acid Increase Bile Acid Efflux in Sandwich-Cultured Human Hepatocytes: Functional Evidence and Mechanisms.
Guo C; LaCerte C; Edwards JE; Brouwer KR; Brouwer KLR
J Pharmacol Exp Ther; 2018 May; 365(2):413-421. PubMed ID: 29487110
[TBL] [Abstract][Full Text] [Related]
2. Comparative potency of obeticholic acid and natural bile acids on FXR in hepatic and intestinal in vitro cell models.
Zhang Y; LaCerte C; Kansra S; Jackson JP; Brouwer KR; Edwards JE
Pharmacol Res Perspect; 2017 Dec; 5(6):. PubMed ID: 29226620
[TBL] [Abstract][Full Text] [Related]
3. Obeticholic acid, a selective farnesoid X receptor agonist, regulates bile acid homeostasis in sandwich-cultured human hepatocytes.
Zhang Y; Jackson JP; St Claire RL; Freeman K; Brouwer KR; Edwards JE
Pharmacol Res Perspect; 2017 Aug; 5(4):. PubMed ID: 28805978
[TBL] [Abstract][Full Text] [Related]
4. The nuclear receptor for bile acids, FXR, transactivates human organic solute transporter-alpha and -beta genes.
Landrier JF; Eloranta JJ; Vavricka SR; Kullak-Ublick GA
Am J Physiol Gastrointest Liver Physiol; 2006 Mar; 290(3):G476-85. PubMed ID: 16269519
[TBL] [Abstract][Full Text] [Related]
5. Obeticholic acid improves hepatic bile acid excretion in patients with primary biliary cholangitis.
Kjærgaard K; Frisch K; Sørensen M; Munk OL; Hofmann AF; Horsager J; Schacht AC; Erickson M; Shapiro D; Keiding S
J Hepatol; 2021 Jan; 74(1):58-65. PubMed ID: 32717289
[TBL] [Abstract][Full Text] [Related]
6. Obeticholic acid, a synthetic bile acid agonist of the farnesoid X receptor, attenuates experimental autoimmune encephalomyelitis.
Ho PP; Steinman L
Proc Natl Acad Sci U S A; 2016 Feb; 113(6):1600-5. PubMed ID: 26811456
[TBL] [Abstract][Full Text] [Related]
7. Role of Organic Solute Transporter Alpha/Beta in Hepatotoxic Bile Acid Transport and Drug Interactions.
Beaudoin JJ; Bezençon J; Sjöstedt N; Fallon JK; Brouwer KLR
Toxicol Sci; 2020 Jul; 176(1):34-35. PubMed ID: 32294204
[TBL] [Abstract][Full Text] [Related]
8. Gene expression profiling in human precision cut liver slices in response to the FXR agonist obeticholic acid.
Ijssennagger N; Janssen AWF; Milona A; Ramos Pittol JM; Hollman DAA; Mokry M; Betzel B; Berends FJ; Janssen IM; van Mil SWC; Kersten S
J Hepatol; 2016 May; 64(5):1158-1166. PubMed ID: 26812075
[TBL] [Abstract][Full Text] [Related]
9. Bile acids induce the expression of the human peroxisome proliferator-activated receptor alpha gene via activation of the farnesoid X receptor.
Pineda Torra I; Claudel T; Duval C; Kosykh V; Fruchart JC; Staels B
Mol Endocrinol; 2003 Feb; 17(2):259-72. PubMed ID: 12554753
[TBL] [Abstract][Full Text] [Related]
10. Mechanistic Modeling of the Hepatic Disposition of Estradiol-17
Ito K; Sjöstedt N; Brouwer KLR
Drug Metab Dispos; 2020 Feb; 48(2):116-122. PubMed ID: 31744810
[TBL] [Abstract][Full Text] [Related]
11. Obeticholic acid protects mice against lipopolysaccharide-induced liver injury and inflammation.
Xiong X; Ren Y; Cui Y; Li R; Wang C; Zhang Y
Biomed Pharmacother; 2017 Dec; 96():1292-1298. PubMed ID: 29174575
[TBL] [Abstract][Full Text] [Related]
12. Differential activation of the human farnesoid X receptor depends on the pattern of expressed isoforms and the bile acid pool composition.
Vaquero J; Monte MJ; Dominguez M; Muntané J; Marin JJ
Biochem Pharmacol; 2013 Oct; 86(7):926-39. PubMed ID: 23928191
[TBL] [Abstract][Full Text] [Related]
13. Farnesoid X Receptor Activation by Obeticholic Acid Elevates Liver Low-Density Lipoprotein Receptor Expression by mRNA Stabilization and Reduces Plasma Low-Density Lipoprotein Cholesterol in Mice.
Singh AB; Dong B; Kraemer FB; Xu Y; Zhang Y; Liu J
Arterioscler Thromb Vasc Biol; 2018 Oct; 38(10):2448-2459. PubMed ID: 30354208
[TBL] [Abstract][Full Text] [Related]
14. A Short Review on Obeticholic Acid: An Effective Modulator of Farnesoid X Receptor.
Narayanan AK; Surendran S; Balakrishnan D; Gopalakrishnan U; Malick S; Valsan A; Philips CA; Watson CJE
Curr Rev Clin Exp Pharmacol; 2024; 19(3):225-233. PubMed ID: 38708917
[TBL] [Abstract][Full Text] [Related]
15. Upregulation of a basolateral FXR-dependent bile acid efflux transporter OSTalpha-OSTbeta in cholestasis in humans and rodents.
Boyer JL; Trauner M; Mennone A; Soroka CJ; Cai SY; Moustafa T; Zollner G; Lee JY; Ballatori N
Am J Physiol Gastrointest Liver Physiol; 2006 Jun; 290(6):G1124-30. PubMed ID: 16423920
[TBL] [Abstract][Full Text] [Related]
16. Alpha-naphthylisothiocyanate modulates hepatobiliary transporters in sandwich-cultured rat hepatocytes.
Guo C; He L; Yao D; A J; Cao B; Ren J; Wang G; Pan G
Toxicol Lett; 2014 Jan; 224(1):93-100. PubMed ID: 24120425
[TBL] [Abstract][Full Text] [Related]
17. The protective effect of obeticholic acid on lipopolysaccharide-induced disorder of maternal bile acid metabolism in pregnant mice.
Zhang C; Gan Y; Lv JW; Qin MQ; Hu WR; Liu ZB; Ma L; Song BD; Li J; Jiang WY; Wang JQ; Wang H; Xu DX
Int Immunopharmacol; 2020 Jun; 83():106442. PubMed ID: 32248018
[TBL] [Abstract][Full Text] [Related]
18. Unaltered Liver Regeneration in Post-Cholestatic Rats Treated with the FXR Agonist Obeticholic Acid.
de Haan LR; Verheij J; van Golen RF; Horneffer-van der Sluis V; Lewis MR; Beuers UHW; van Gulik TM; Olde Damink SWM; Schaap FG; Heger M; Olthof PB
Biomolecules; 2021 Feb; 11(2):. PubMed ID: 33578971
[No Abstract] [Full Text] [Related]
19. The organic solute transporters alpha and beta are induced by hypoxia in human hepatocytes.
Schaffner CA; Mwinyi J; Gai Z; Thasler WE; Eloranta JJ; Kullak-Ublick GA
Liver Int; 2015 Apr; 35(4):1152-61. PubMed ID: 24703425
[TBL] [Abstract][Full Text] [Related]
20. Farnesoid X Receptor Activation Stimulates Organic Cations Transport in Human Renal Proximal Tubular Cells.
Wongwan T; Chatsudthipong V; Soodvilai S
Int J Mol Sci; 2020 Aug; 21(17):. PubMed ID: 32846898
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]