BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

424 related articles for article (PubMed ID: 29491012)

  • 1. Cell-Specific Deletion of PGC-1α from Medium Spiny Neurons Causes Transcriptional Alterations and Age-Related Motor Impairment.
    McMeekin LJ; Li Y; Fox SN; Rowe GC; Crossman DK; Day JJ; Li Y; Detloff PJ; Cowell RM
    J Neurosci; 2018 Mar; 38(13):3273-3286. PubMed ID: 29491012
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Developmental alterations in motor coordination and medium spiny neuron markers in mice lacking pgc-1α.
    Lucas EK; Dougherty SE; McMeekin LJ; Trinh AT; Reid CS; Cowell RM
    PLoS One; 2012; 7(8):e42878. PubMed ID: 22916173
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Transcriptional repression of PGC-1alpha by mutant huntingtin leads to mitochondrial dysfunction and neurodegeneration.
    Cui L; Jeong H; Borovecki F; Parkhurst CN; Tanese N; Krainc D
    Cell; 2006 Oct; 127(1):59-69. PubMed ID: 17018277
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A Role for Peroxisome Proliferator-Activated Receptor Gamma Coactivator-1α in Nucleus Accumbens Neuron Subtypes in Cocaine Action.
    Chandra R; Engeln M; Francis TC; Konkalmatt P; Patel D; Lobo MK
    Biol Psychiatry; 2017 Apr; 81(7):564-572. PubMed ID: 27939396
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Impairment of PGC-1alpha expression, neuropathology and hepatic steatosis in a transgenic mouse model of Huntington's disease following chronic energy deprivation.
    Chaturvedi RK; Calingasan NY; Yang L; Hennessey T; Johri A; Beal MF
    Hum Mol Genet; 2010 Aug; 19(16):3190-205. PubMed ID: 20529956
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A Role for PGC-1α in Transcription and Excitability of Neocortical and Hippocampal Excitatory Neurons.
    McMeekin LJ; Bartley AF; Bohannon AS; Adlaf EW; van Groen T; Boas SM; Fox SN; Detloff PJ; Crossman DK; Overstreet-Wadiche LS; Hablitz JJ; Dobrunz LE; Cowell RM
    Neuroscience; 2020 May; 435():73-94. PubMed ID: 32222555
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Enhanced Store-Operated Calcium Entry Leads to Striatal Synaptic Loss in a Huntington's Disease Mouse Model.
    Wu J; Ryskamp DA; Liang X; Egorova P; Zakharova O; Hung G; Bezprozvanny I
    J Neurosci; 2016 Jan; 36(1):125-41. PubMed ID: 26740655
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Thermoregulatory and metabolic defects in Huntington's disease transgenic mice implicate PGC-1alpha in Huntington's disease neurodegeneration.
    Weydt P; Pineda VV; Torrence AE; Libby RT; Satterfield TF; Lazarowski ER; Gilbert ML; Morton GJ; Bammler TK; Strand AD; Cui L; Beyer RP; Easley CN; Smith AC; Krainc D; Luquet S; Sweet IR; Schwartz MW; La Spada AR
    Cell Metab; 2006 Nov; 4(5):349-62. PubMed ID: 17055784
    [TBL] [Abstract][Full Text] [Related]  

  • 9. PGC-1α negatively regulates extrasynaptic NMDAR activity and excitotoxicity.
    Puddifoot C; Martel MA; Soriano FX; Camacho A; Vidal-Puig A; Wyllie DJ; Hardingham GE
    J Neurosci; 2012 May; 32(20):6995-7000. PubMed ID: 22593067
    [TBL] [Abstract][Full Text] [Related]  

  • 10. In vivo cell-autonomous transcriptional abnormalities revealed in mice expressing mutant huntingtin in striatal but not cortical neurons.
    Thomas EA; Coppola G; Tang B; Kuhn A; Kim S; Geschwind DH; Brown TB; Luthi-Carter R; Ehrlich ME
    Hum Mol Genet; 2011 Mar; 20(6):1049-60. PubMed ID: 21177255
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Single-Nucleus RNA-Seq Reveals Dysregulation of Striatal Cell Identity Due to Huntington's Disease Mutations.
    Malaiya S; Cortes-Gutierrez M; Herb BR; Coffey SR; Legg SRW; Cantle JP; Colantuoni C; Carroll JB; Ament SA
    J Neurosci; 2021 Jun; 41(25):5534-5552. PubMed ID: 34011527
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Mitogen- and stress-activated protein kinase 1-induced neuroprotection in Huntington's disease: role on chromatin remodeling at the PGC-1-alpha promoter.
    Martin E; Betuing S; Pagès C; Cambon K; Auregan G; Deglon N; Roze E; Caboche J
    Hum Mol Genet; 2011 Jun; 20(12):2422-34. PubMed ID: 21493629
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Mitochondrial Dysfunction in Huntington's Disease; Interplay Between HSF1, p53 and PGC-1α Transcription Factors.
    Intihar TA; Martinez EA; Gomez-Pastor R
    Front Cell Neurosci; 2019; 13():103. PubMed ID: 30941017
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Neocortical expression of mutant huntingtin is not required for alterations in striatal gene expression or motor dysfunction in a transgenic mouse.
    Brown TB; Bogush AI; Ehrlich ME
    Hum Mol Genet; 2008 Oct; 17(20):3095-104. PubMed ID: 18632688
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Dysregulation of PGC-1α-Dependent Transcriptional Programs in Neurological and Developmental Disorders: Therapeutic Challenges and Opportunities.
    McMeekin LJ; Fox SN; Boas SM; Cowell RM
    Cells; 2021 Feb; 10(2):. PubMed ID: 33572179
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Transducer of regulated CREB-binding proteins (TORCs) transcription and function is impaired in Huntington's disease.
    Chaturvedi RK; Hennessey T; Johri A; Tiwari SK; Mishra D; Agarwal S; Kim YS; Beal MF
    Hum Mol Genet; 2012 Aug; 21(15):3474-88. PubMed ID: 22589249
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Neuroprotective effects of PPAR-γ agonist rosiglitazone in N171-82Q mouse model of Huntington's disease.
    Jin J; Albertz J; Guo Z; Peng Q; Rudow G; Troncoso JC; Ross CA; Duan W
    J Neurochem; 2013 May; 125(3):410-9. PubMed ID: 23373812
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Adult Conditional Knockout of PGC-1α Leads to Loss of Dopamine Neurons.
    Jiang H; Kang SU; Zhang S; Karuppagounder S; Xu J; Lee YK; Kang BG; Lee Y; Zhang J; Pletnikova O; Troncoso JC; Pirooznia S; Andrabi SA; Dawson VL; Dawson TM
    eNeuro; 2016; 3(4):. PubMed ID: 27622213
    [TBL] [Abstract][Full Text] [Related]  

  • 19. PGC-1α at the intersection of bioenergetics regulation and neuron function: from Huntington's disease to Parkinson's disease and beyond.
    Tsunemi T; La Spada AR
    Prog Neurobiol; 2012 May; 97(2):142-51. PubMed ID: 22100502
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Activating mitochondrial regulator PGC-1α expression by astrocytic NGF is a therapeutic strategy for Huntington's disease.
    Chen LW; Horng LY; Wu CL; Sung HC; Wu RT
    Neuropharmacology; 2012 Sep; 63(4):719-32. PubMed ID: 22633948
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 22.