These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

393 related articles for article (PubMed ID: 29491392)

  • 1. Disruption of ER-mitochondria signalling in fronto-temporal dementia and related amyotrophic lateral sclerosis.
    Lau DHW; Hartopp N; Welsh NJ; Mueller S; Glennon EB; Mórotz GM; Annibali A; Gomez-Suaga P; Stoica R; Paillusson S; Miller CCJ
    Cell Death Dis; 2018 Feb; 9(3):327. PubMed ID: 29491392
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Disruption of ER-mitochondria tethering and signalling in C9orf72-associated amyotrophic lateral sclerosis and frontotemporal dementia.
    Gomez-Suaga P; Mórotz GM; Markovinovic A; Martín-Guerrero SM; Preza E; Arias N; Mayl K; Aabdien A; Gesheva V; Nishimura A; Annibali A; Lee Y; Mitchell JC; Wray S; Shaw C; Noble W; Miller CCJ
    Aging Cell; 2022 Feb; 21(2):e13549. PubMed ID: 35026048
    [TBL] [Abstract][Full Text] [Related]  

  • 3. C9orf72 ALS-FTD: recent evidence for dysregulation of the autophagy-lysosome pathway at multiple levels.
    Beckers J; Tharkeshwar AK; Van Damme P
    Autophagy; 2021 Nov; 17(11):3306-3322. PubMed ID: 33632058
    [TBL] [Abstract][Full Text] [Related]  

  • 4. C9orf72 Hexanucleotide Expansions Are Associated with Altered Endoplasmic Reticulum Calcium Homeostasis and Stress Granule Formation in Induced Pluripotent Stem Cell-Derived Neurons from Patients with Amyotrophic Lateral Sclerosis and Frontotemporal Dementia.
    Dafinca R; Scaber J; Ababneh N; Lalic T; Weir G; Christian H; Vowles J; Douglas AG; Fletcher-Jones A; Browne C; Nakanishi M; Turner MR; Wade-Martins R; Cowley SA; Talbot K
    Stem Cells; 2016 Aug; 34(8):2063-78. PubMed ID: 27097283
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Clinical and neuropathologic heterogeneity of c9FTD/ALS associated with hexanucleotide repeat expansion in C9ORF72.
    Murray ME; DeJesus-Hernandez M; Rutherford NJ; Baker M; Duara R; Graff-Radford NR; Wszolek ZK; Ferman TJ; Josephs KA; Boylan KB; Rademakers R; Dickson DW
    Acta Neuropathol; 2011 Dec; 122(6):673-90. PubMed ID: 22083254
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Stable transgenic C9orf72 zebrafish model key aspects of the ALS/FTD phenotype and reveal novel pathological features.
    Shaw MP; Higginbottom A; McGown A; Castelli LM; James E; Hautbergue GM; Shaw PJ; Ramesh TM
    Acta Neuropathol Commun; 2018 Nov; 6(1):125. PubMed ID: 30454072
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The mTORC2/AKT/VCP axis is associated with quality control of the stalled translation of poly(GR) dipeptide repeats in C9-ALS/FTD.
    Li Y; Geng J; Rimal S; Wang H; Liu X; Lu B; Li S
    J Biol Chem; 2023 Mar; 299(3):102995. PubMed ID: 36764521
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Molecular Mechanisms of Neurodegeneration Related to
    Babić Leko M; Župunski V; Kirincich J; Smilović D; Hortobágyi T; Hof PR; Šimić G
    Behav Neurol; 2019; 2019():2909168. PubMed ID: 30774737
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Nuclear transport dysfunction: a common theme in amyotrophic lateral sclerosis and frontotemporal dementia.
    Jovičić A; Paul JW; Gitler AD
    J Neurochem; 2016 Aug; 138 Suppl 1():134-44. PubMed ID: 27087014
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Stimulating VAPB-PTPIP51 ER-mitochondria tethering corrects FTD/ALS mutant TDP43 linked Ca
    Markovinovic A; Martín-Guerrero SM; Mórotz GM; Salam S; Gomez-Suaga P; Paillusson S; Greig J; Lee Y; Mitchell JC; Noble W; Miller CCJ
    Acta Neuropathol Commun; 2024 Feb; 12(1):32. PubMed ID: 38395965
    [TBL] [Abstract][Full Text] [Related]  

  • 11. ALS/FTD-associated FUS activates GSK-3β to disrupt the VAPB-PTPIP51 interaction and ER-mitochondria associations.
    Stoica R; Paillusson S; Gomez-Suaga P; Mitchell JC; Lau DH; Gray EH; Sancho RM; Vizcay-Barrena G; De Vos KJ; Shaw CE; Hanger DP; Noble W; Miller CC
    EMBO Rep; 2016 Sep; 17(9):1326-42. PubMed ID: 27418313
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Two FTD-ALS genes converge on the endosomal pathway to induce TDP-43 pathology and degeneration.
    Shao W; Todd TW; Wu Y; Jones CY; Tong J; Jansen-West K; Daughrity LM; Park J; Koike Y; Kurti A; Yue M; Castanedes-Casey M; Del Rosso G; Dunmore JA; Zanetti Alepuz D; Oskarsson B; Dickson DW; Cook CN; Prudencio M; Gendron TF; Fryer JD; Zhang YJ; Petrucelli L
    Science; 2022 Oct; 378(6615):94-99. PubMed ID: 36201573
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Dipeptide repeat protein inclusions are rare in the spinal cord and almost absent from motor neurons in C9ORF72 mutant amyotrophic lateral sclerosis and are unlikely to cause their degeneration.
    Gomez-Deza J; Lee YB; Troakes C; Nolan M; Al-Sarraj S; Gallo JM; Shaw CE
    Acta Neuropathol Commun; 2015 Jun; 3():38. PubMed ID: 26108573
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Cryptic exon detection and transcriptomic changes revealed in single-nuclei RNA sequencing of C9ORF72 patients spanning the ALS-FTD spectrum.
    Gittings LM; Alsop EB; Antone J; Singer M; Whitsett TG; Sattler R; Van Keuren-Jensen K
    Acta Neuropathol; 2023 Sep; 146(3):433-450. PubMed ID: 37466726
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Role of the C9ORF72 Gene in the Pathogenesis of Amyotrophic Lateral Sclerosis and Frontotemporal Dementia.
    Hao Z; Wang R; Ren H; Wang G
    Neurosci Bull; 2020 Sep; 36(9):1057-1070. PubMed ID: 32860626
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Molecular pathology and genetic advances in amyotrophic lateral sclerosis: an emerging molecular pathway and the significance of glial pathology.
    Ince PG; Highley JR; Kirby J; Wharton SB; Takahashi H; Strong MJ; Shaw PJ
    Acta Neuropathol; 2011 Dec; 122(6):657-71. PubMed ID: 22105541
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Gene-specific mitochondria dysfunctions in human TARDBP and C9ORF72 fibroblasts.
    Onesto E; Colombrita C; Gumina V; Borghi MO; Dusi S; Doretti A; Fagiolari G; Invernizzi F; Moggio M; Tiranti V; Silani V; Ratti A
    Acta Neuropathol Commun; 2016 May; 4(1):47. PubMed ID: 27151080
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Proteostasis deregulation as a driver of C9ORF72 pathogenesis.
    Torres P; Cabral-Miranda F; Gonzalez-Teuber V; Hetz C
    J Neurochem; 2021 Dec; 159(6):941-957. PubMed ID: 34679204
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The role of heat shock proteins in Amyotrophic Lateral Sclerosis: The therapeutic potential of Arimoclomol.
    Kalmar B; Lu CH; Greensmith L
    Pharmacol Ther; 2014 Jan; 141(1):40-54. PubMed ID: 23978556
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Clinical and neuropathological features of ALS/FTD with TIA1 mutations.
    Hirsch-Reinshagen V; Pottier C; Nicholson AM; Baker M; Hsiung GR; Krieger C; Sengdy P; Boylan KB; Dickson DW; Mesulam M; Weintraub S; Bigio E; Zinman L; Keith J; Rogaeva E; Zivkovic SA; Lacomis D; Taylor JP; Rademakers R; Mackenzie IRA
    Acta Neuropathol Commun; 2017 Dec; 5(1):96. PubMed ID: 29216908
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 20.