These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

175 related articles for article (PubMed ID: 29518414)

  • 1. Profiling the in vitro drug-resistance mechanism of influenza A viruses towards the AM2-S31N proton channel blockers.
    Musharrafieh R; Ma C; Wang J
    Antiviral Res; 2018 May; 153():10-22. PubMed ID: 29518414
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The L46P mutant confers a novel allosteric mechanism of resistance toward the influenza A virus M2 S31N proton channel blockers.
    Musharrafieh R; Lagarias PI; Ma C; Tan GS; Kolocouris A; Wang J
    Mol Pharmacol; 2019 Aug; 96(2):148-157. PubMed ID: 31175183
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Pharmacological Characterization of the Spectrum of Antiviral Activity and Genetic Barrier to Drug Resistance of M2-S31N Channel Blockers.
    Ma C; Zhang J; Wang J
    Mol Pharmacol; 2016 Sep; 90(3):188-98. PubMed ID: 27385729
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Discovery of M2 channel blockers targeting the drug-resistant double mutants M2-S31N/L26I and M2-S31N/V27A from the influenza A viruses.
    Musharrafieh R; Ma C; Wang J
    Eur J Pharm Sci; 2020 Jan; 141():105124. PubMed ID: 31669761
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Expeditious Lead Optimization of Isoxazole-Containing Influenza A Virus M2-S31N Inhibitors Using the Suzuki-Miyaura Cross-Coupling Reaction.
    Li F; Hu Y; Wang Y; Ma C; Wang J
    J Med Chem; 2017 Feb; 60(4):1580-1590. PubMed ID: 28182419
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Discovery of Potent Antivirals against Amantadine-Resistant Influenza A Viruses by Targeting the M2-S31N Proton Channel.
    Li F; Ma C; Hu Y; Wang Y; Wang J
    ACS Infect Dis; 2016 Oct; 2(10):726-733. PubMed ID: 27657178
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Flipping in the pore: discovery of dual inhibitors that bind in different orientations to the wild-type versus the amantadine-resistant S31N mutant of the influenza A virus M2 proton channel.
    Wu Y; Canturk B; Jo H; Ma C; Gianti E; Klein ML; Pinto LH; Lamb RA; Fiorin G; Wang J; DeGrado WF
    J Am Chem Soc; 2014 Dec; 136(52):17987-95. PubMed ID: 25470189
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Structure-Property Relationship Studies of Influenza A Virus AM2-S31N Proton Channel Blockers.
    Hu Y; Hau RK; Wang Y; Tuohy P; Zhang Y; Xu S; Ma C; Wang J
    ACS Med Chem Lett; 2018 Nov; 9(11):1111-1116. PubMed ID: 30429954
    [TBL] [Abstract][Full Text] [Related]  

  • 9. In Vitro Pharmacokinetic Optimizations of AM2-S31N Channel Blockers Led to the Discovery of Slow-Binding Inhibitors with Potent Antiviral Activity against Drug-Resistant Influenza A Viruses.
    Wang Y; Hu Y; Xu S; Zhang Y; Musharrafieh R; Hau RK; Ma C; Wang J
    J Med Chem; 2018 Feb; 61(3):1074-1085. PubMed ID: 29341607
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Design and expeditious synthesis of organosilanes as potent antivirals targeting multidrug-resistant influenza A viruses.
    Hu Y; Wang Y; Li F; Ma C; Wang J
    Eur J Med Chem; 2017 Jul; 135():70-76. PubMed ID: 28433777
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Generation and characterization of recombinant influenza A (H1N1) viruses harboring amantadine resistance mutations.
    Abed Y; Goyette N; Boivin G
    Antimicrob Agents Chemother; 2005 Feb; 49(2):556-9. PubMed ID: 15673732
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Discovery of novel dual inhibitors of the wild-type and the most prevalent drug-resistant mutant, S31N, of the M2 proton channel from influenza A virus.
    Wang J; Ma C; Wang J; Jo H; Canturk B; Fiorin G; Pinto LH; Lamb RA; Klein ML; DeGrado WF
    J Med Chem; 2013 Apr; 56(7):2804-12. PubMed ID: 23437766
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Aminoadamantanes with persistent in vitro efficacy against H1N1 (2009) influenza A.
    Kolocouris A; Tzitzoglaki C; Johnson FB; Zell R; Wright AK; Cross TA; Tietjen I; Fedida D; Busath DD
    J Med Chem; 2014 Jun; 57(11):4629-39. PubMed ID: 24793875
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Rational design of a deuterium-containing M2-S31N channel blocker UAWJ280 with
    Cáceres CJ; Hu Y; Cárdenas-García S; Wu X; Tan H; Carnaccini S; Gay LC; Geiger G; Ma C; Zhang QY; Rajao D; Perez DR; Wang J
    Emerg Microbes Infect; 2021 Dec; 10(1):1832-1848. PubMed ID: 34427541
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Comprehensive assessment of 2009 pandemic influenza A (H1N1) virus drug susceptibility in vitro.
    Gubareva LV; Trujillo AA; Okomo-Adhiambo M; Mishin VP; Deyde VM; Sleeman K; Nguyen HT; Sheu TG; Garten RJ; Shaw MW; Fry AM; Klimov AI
    Antivir Ther; 2010; 15(8):1151-9. PubMed ID: 21149922
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Influenza A viruses of swine circulating in the United States during 2009-2014 are susceptible to neuraminidase inhibitors but show lineage-dependent resistance to adamantanes.
    Baranovich T; Bahl J; Marathe BM; Culhane M; Stigger-Rosser E; Darnell D; Kaplan BS; Lowe JF; Webby RJ; Govorkova EA
    Antiviral Res; 2015 May; 117():10-9. PubMed ID: 25701593
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Genotypic and phenotypic resistance of pandemic A/H1N1 influenza viruses circulating in Germany.
    Duwe SC; Wedde M; Birkner P; Schweiger B
    Antiviral Res; 2011 Jan; 89(1):115-8. PubMed ID: 21070812
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Computational investigation of drug-resistant mutant of M2 proton channel (S31N) against rimantadine.
    Karthick V; Ramanathan K
    Cell Biochem Biophys; 2014 Nov; 70(2):975-82. PubMed ID: 24807842
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Amantadine- and oseltamivir-resistant variants of influenza A viruses in Thailand.
    Bai GR; Chittaganpitch M; Kanai Y; Li YG; Auwanit W; Ikuta K; Sawanpanyalert P
    Biochem Biophys Res Commun; 2009 Dec; 390(3):897-901. PubMed ID: 19850010
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Virtual screening and molecular growth guide the design of inhibitors for the influenza virus drug-resistant mutant M2-V27A/S31N.
    Deng C; Wang X; Wang T; Liu W; Yuan X; Huang Y; Cao S
    J Biomol Struct Dyn; 2024 Jul; 42(10):5253-5267. PubMed ID: 37424098
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.