355 related articles for article (PubMed ID: 29521213)
1. Advances in Spirocyclic Hybrids: Chemistry and Medicinal Actions.
Benabdallah M; Talhi O; Nouali F; Choukchou-Braham N; Bachari K; Silva AMS
Curr Med Chem; 2018; 25(31):3748-3767. PubMed ID: 29521213
[TBL] [Abstract][Full Text] [Related]
2. Design and synthesis of 2-phenyl-1,4-dioxa-spiro[4.5]deca-6,9-dien-8-ones as potential anticancer agents starting from cytotoxic spiromamakone A.
Fuse S; Inaba K; Takagi M; Tanaka M; Hirokawa T; Johmoto K; Uekusa H; Shin-Ya K; Takahashi T; Doi T
Eur J Med Chem; 2013 Aug; 66():180-4. PubMed ID: 23792765
[TBL] [Abstract][Full Text] [Related]
3. Synthesis of new class of spirocarbocycle derivatives by multicomponent domino reaction and their evaluation for antimicrobial, anticancer activity and molecular docking studies.
Sudhapriya N; Perumal PT; Balachandran C; Ignacimuthu S; Sangeetha M; Doble M
Eur J Med Chem; 2014 Aug; 83():190-207. PubMed ID: 24956555
[TBL] [Abstract][Full Text] [Related]
4. Synthesis of Spiro[indole-3,5'-isoxazoles] with Anticancer Activity via a Formal [4 + 1]-Spirocyclization of Nitroalkenes to Indoles.
Aksenov AV; Aksenov DA; Arutiunov NA; Aksenov NA; Aleksandrova EV; Zhao Z; Du L; Kornienko A; Rubin M
J Org Chem; 2019 Jun; 84(11):7123-7137. PubMed ID: 31070030
[TBL] [Abstract][Full Text] [Related]
5. The use of spirocyclic scaffolds in drug discovery.
Zheng Y; Tice CM; Singh SB
Bioorg Med Chem Lett; 2014 Aug; 24(16):3673-82. PubMed ID: 25052427
[TBL] [Abstract][Full Text] [Related]
6. Spirocyclic nucleosides in medicinal chemistry: an overview.
Soengas RG; Silva S
Mini Rev Med Chem; 2012 Dec; 12(14):1485-96. PubMed ID: 22827180
[TBL] [Abstract][Full Text] [Related]
7. Pteridic acids C-G spirocyclic polyketides from the marine-derived Streptomyces sp. SCSGAA 0027.
Nong XH; Wei XY; Qi SH
J Antibiot (Tokyo); 2017 Nov; 70(11):1047-1052. PubMed ID: 28951600
[TBL] [Abstract][Full Text] [Related]
8. Design and synthesis of spirocyclic compounds as HCV replication inhibitors by targeting viral NS4B protein.
Tai VW; Garrido D; Price DJ; Maynard A; Pouliot JJ; Xiong Z; Seal JW; Creech KL; Kryn LH; Baughman TM; Peat AJ
Bioorg Med Chem Lett; 2014 May; 24(10):2288-94. PubMed ID: 24731273
[TBL] [Abstract][Full Text] [Related]
9. Synthesis of some new heterobicyclic compounds containing spiro-1,2,4-triazine moiety as potential anti HIV and anticancer agents.
Abdel-Rahman RM; Seada M; Fawzy M; el-Baz I
Boll Chim Farm; 1994 Jun; 133(6):374-80. PubMed ID: 7917184
[TBL] [Abstract][Full Text] [Related]
10. Recent advances in the chemistry and biology of pyridopyrimidines.
Buron F; Mérour JY; Akssira M; Guillaumet G; Routier S
Eur J Med Chem; 2015 May; 95():76-95. PubMed ID: 25794791
[TBL] [Abstract][Full Text] [Related]
11. Synthetic and biological studies on the spiro-mamakone system.
Murphy AC; Devenish SR; Muscroft-Taylor AC; Blunt JW; Munro MH
Org Biomol Chem; 2008 Oct; 6(20):3854-62. PubMed ID: 18843418
[TBL] [Abstract][Full Text] [Related]
12. Carbazole Scaffold in Medicinal Chemistry and Natural Products: A Review from 2010-2015.
Tsutsumi LS; Gündisch D; Sun D
Curr Top Med Chem; 2016; 16(11):1290-313. PubMed ID: 26369811
[TBL] [Abstract][Full Text] [Related]
13. Synthesis of some new 1,6-dihydro-3-substituted-6-spiro-(9'-fluorene)-1,2,4-triazin-5-( 4H)-on es as potential anti HIV and anticancer drugs.
Abdel-Rahman RM; Seada M; Fawzy M; el Baz I
Boll Chim Farm; 1994 Jun; 133(6):381-8. PubMed ID: 7917185
[TBL] [Abstract][Full Text] [Related]
14. A Synthesis of a Spirocyclic Macrocyclic Protease Inhibitor for the Treatment of Hepatitis C.
Chung CK; Cleator E; Dumas AM; Hicks JD; Humphrey GR; Maligres PE; Nolting AF; Rivera N; Ruck RT; Shevlin M
Org Lett; 2016 Mar; 18(6):1394-7. PubMed ID: 26950496
[TBL] [Abstract][Full Text] [Related]
15. Isatin Derived Spirocyclic Analogues with α-Methylene-γ-butyrolactone as Anticancer Agents: A Structure-Activity Relationship Study.
Rana S; Blowers EC; Tebbe C; Contreras JI; Radhakrishnan P; Kizhake S; Zhou T; Rajule RN; Arnst JL; Munkarah AR; Rattan R; Natarajan A
J Med Chem; 2016 May; 59(10):5121-7. PubMed ID: 27077228
[TBL] [Abstract][Full Text] [Related]
16. Synthesis of some new 1,6-dihydro-3-substituted 6-spiro-(9'-fluorene)-1,2,4-triazin-5-(4H)-ones as potential anti HIV and anticancer drugs.
Abdel-Rahman RM; Seada M; Fawzy M; el-Baz I
Pharmazie; 1994 Oct; 49(10):729-33. PubMed ID: 7816899
[TBL] [Abstract][Full Text] [Related]
17. Charting Biologically Relevant Spirocyclic Compound Space.
Müller G; Berkenbosch T; Benningshof JC; Stumpfe D; Bajorath J
Chemistry; 2017 Jan; 23(3):703-710. PubMed ID: 27859909
[TBL] [Abstract][Full Text] [Related]
18. Spiro-oxindole derivative 5-chloro-4',5'-diphenyl-3'-(4-(2-(piperidin-1-yl) ethoxy) benzoyl) spiro[indoline-3,2'-pyrrolidin]-2-one triggers apoptosis in breast cancer cells via restoration of p53 function.
Saxena R; Gupta G; Manohar M; Debnath U; Popli P; Prabhakar YS; Konwar R; Kumar S; Kumar A; Dwivedi A
Int J Biochem Cell Biol; 2016 Jan; 70():105-17. PubMed ID: 26556313
[TBL] [Abstract][Full Text] [Related]
19. Pyrazole containing natural products: synthetic preview and biological significance.
Kumar V; Kaur K; Gupta GK; Sharma AK
Eur J Med Chem; 2013 Nov; 69():735-53. PubMed ID: 24099993
[TBL] [Abstract][Full Text] [Related]
20. Thiazolo[4,5-d]pyrimidines as a privileged scaffold in drug discovery.
Kuppast B; Fahmy H
Eur J Med Chem; 2016 May; 113():198-213. PubMed ID: 26942627
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
