213 related articles for article (PubMed ID: 29523541)
21. DNA damage-induced phosphorylation of MdmX at serine 367 activates p53 by targeting MdmX for Mdm2-dependent degradation.
Okamoto K; Kashima K; Pereg Y; Ishida M; Yamazaki S; Nota A; Teunisse A; Migliorini D; Kitabayashi I; Marine JC; Prives C; Shiloh Y; Jochemsen AG; Taya Y
Mol Cell Biol; 2005 Nov; 25(21):9608-20. PubMed ID: 16227609
[TBL] [Abstract][Full Text] [Related]
22. Functional analysis and consequences of Mdm2 E3 ligase inhibition in human tumor cells.
Wade M; Li YC; Matani AS; Braun SM; Milanesi F; Rodewald LW; Wahl GM
Oncogene; 2012 Nov; 31(45):4789-97. PubMed ID: 22266850
[TBL] [Abstract][Full Text] [Related]
23. PELI1: key players in the oncogenic characteristics of pancreatic Cancer.
Fei X; Zhu C; Liu P; Liu S; Ren L; Lu R; Hou J; Gao Y; Wang X; Pan Y
J Exp Clin Cancer Res; 2024 Mar; 43(1):91. PubMed ID: 38528516
[TBL] [Abstract][Full Text] [Related]
24. MdmX is a RING finger ubiquitin ligase capable of synergistically enhancing Mdm2 ubiquitination.
Badciong JC; Haas AL
J Biol Chem; 2002 Dec; 277(51):49668-75. PubMed ID: 12393902
[TBL] [Abstract][Full Text] [Related]
25. Mdmx stabilizes p53 and Mdm2 via two distinct mechanisms.
Stad R; Little NA; Xirodimas DP; Frenk R; van der Eb AJ; Lane DP; Saville MK; Jochemsen AG
EMBO Rep; 2001 Nov; 2(11):1029-34. PubMed ID: 11606419
[TBL] [Abstract][Full Text] [Related]
26. Effects of MdmX on Mdm2-mediated downregulation of pRB.
Uchida C; Miwa S; Isobe T; Kitagawa K; Hattori T; Oda T; Yasuda H; Kitagawa M
FEBS Lett; 2006 Mar; 580(7):1753-8. PubMed ID: 16510145
[TBL] [Abstract][Full Text] [Related]
27. Targeting RING domains of Mdm2-MdmX E3 complex activates apoptotic arm of the p53 pathway in leukemia/lymphoma cells.
Wu W; Xu C; Ling X; Fan C; Buckley BP; Chernov MV; Ellis L; Li F; Muñoz IG; Wang X
Cell Death Dis; 2015 Dec; 6(12):e2035. PubMed ID: 26720344
[TBL] [Abstract][Full Text] [Related]
28. ATM and Chk2-dependent phosphorylation of MDMX contribute to p53 activation after DNA damage.
Chen L; Gilkes DM; Pan Y; Lane WS; Chen J
EMBO J; 2005 Oct; 24(19):3411-22. PubMed ID: 16163388
[TBL] [Abstract][Full Text] [Related]
29. Turning the RING domain protein MdmX into an active ubiquitin-protein ligase.
Iyappan S; Wollscheid HP; Rojas-Fernandez A; Marquardt A; Tang HC; Singh RK; Scheffner M
J Biol Chem; 2010 Oct; 285(43):33065-33072. PubMed ID: 20705607
[TBL] [Abstract][Full Text] [Related]
30. Discovery of Mdm2-MdmX E3 ligase inhibitors using a cell-based ubiquitination assay.
Herman AG; Hayano M; Poyurovsky MV; Shimada K; Skouta R; Prives C; Stockwell BR
Cancer Discov; 2011 Sep; 1(4):312-25. PubMed ID: 22586610
[TBL] [Abstract][Full Text] [Related]
31. MDMX promotes proteasomal turnover of p21 at G1 and early S phases independently of, but in cooperation with, MDM2.
Jin Y; Zeng SX; Sun XX; Lee H; Blattner C; Xiao Z; Lu H
Mol Cell Biol; 2008 Feb; 28(4):1218-29. PubMed ID: 18086887
[TBL] [Abstract][Full Text] [Related]
32. Inferring Leading Interactions in the p53/Mdm2/Mdmx Circuit through Live-Cell Imaging and Modeling.
Heltberg ML; Chen SH; Jiménez A; Jambhekar A; Jensen MH; Lahav G
Cell Syst; 2019 Dec; 9(6):548-558.e5. PubMed ID: 31812692
[TBL] [Abstract][Full Text] [Related]
33. Human epidermal growth factor receptor 4 (Her4) Suppresses p53 Protein via Targeting the MDMX-MDM2 Protein Complex: IMPLICATION OF A NOVEL MDMX SER-314 PHOSPHOSITE.
Gerarduzzi C; de Polo A; Liu XS; El Kharbili M; Little JB; Yuan ZM
J Biol Chem; 2016 Dec; 291(50):25937-25949. PubMed ID: 27777309
[TBL] [Abstract][Full Text] [Related]
34. Mutual dependence of MDM2 and MDMX in their functional inactivation of p53.
Gu J; Kawai H; Nie L; Kitao H; Wiederschain D; Jochemsen AG; Parant J; Lozano G; Yuan ZM
J Biol Chem; 2002 May; 277(22):19251-4. PubMed ID: 11953423
[TBL] [Abstract][Full Text] [Related]
35. FL118 induces p53-dependent senescence in colorectal cancer cells by promoting degradation of MdmX.
Ling X; Xu C; Fan C; Zhong K; Li F; Wang X
Cancer Res; 2014 Dec; 74(24):7487-97. PubMed ID: 25512388
[TBL] [Abstract][Full Text] [Related]
36. Identification of ribosomal protein S25 (RPS25)-MDM2-p53 regulatory feedback loop.
Zhang X; Wang W; Wang H; Wang MH; Xu W; Zhang R
Oncogene; 2013 May; 32(22):2782-91. PubMed ID: 22777350
[TBL] [Abstract][Full Text] [Related]
37. The Roles of MDM2 and MDMX in Cancer.
Karni-Schmidt O; Lokshin M; Prives C
Annu Rev Pathol; 2016 May; 11():617-44. PubMed ID: 27022975
[TBL] [Abstract][Full Text] [Related]
38. Regulation of MDMX nuclear import and degradation by Chk2 and 14-3-3.
LeBron C; Chen L; Gilkes DM; Chen J
EMBO J; 2006 Mar; 25(6):1196-206. PubMed ID: 16511560
[TBL] [Abstract][Full Text] [Related]
39. A critical role for noncoding 5S rRNA in regulating Mdmx stability.
Li M; Gu W
Mol Cell; 2011 Sep; 43(6):1023-32. PubMed ID: 21925390
[TBL] [Abstract][Full Text] [Related]
40. Induction of p53 expression and apoptosis by a recombinant dual-target MDM2/MDMX inhibitory protein in wild-type p53 breast cancer cells.
Geng QQ; Dong DF; Chen NZ; Wu YY; Li EX; Wang J; Wang SM
Int J Oncol; 2013 Dec; 43(6):1935-42. PubMed ID: 24126697
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
