BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

135 related articles for article (PubMed ID: 29524040)

  • 1. Site-Directed Mutagenesis of Cytochrome P450 2D6 and 2C19 Enzymes: Expression and Spectral Characterization of Naturally Occurring Allelic Variants.
    Dong AN; Pan Y; Palanisamy UD; Yiap BC; Ahemad N; Ong CE
    Appl Biochem Biotechnol; 2018 Sep; 186(1):132-144. PubMed ID: 29524040
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Functional co-expression of CYP2D6 and human NADPH-cytochrome P450 reductase in Escherichia coli.
    Pritchard MP; Glancey MJ; Blake JA; Gilham DE; Burchell B; Wolf CR; Friedberg T
    Pharmacogenetics; 1998 Feb; 8(1):33-42. PubMed ID: 9511179
    [TBL] [Abstract][Full Text] [Related]  

  • 3. In Vitro Functional Characterisation of Cytochrome P450 (CYP) 2C19 Allelic Variants CYP2C19*23 and CYP2C19*24.
    Lau PS; Leong KV; Ong CE; Dong AN; Pan Y
    Biochem Genet; 2017 Feb; 55(1):48-62. PubMed ID: 27578295
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Functional and structural characterisation of common cytochrome P450 2D6 allelic variants-roles of Pro34 and Thr107 in catalysis and inhibition.
    Dong AN; Ahemad N; Pan Y; Palanisamy UD; Yiap BC; Ong CE
    Naunyn Schmiedebergs Arch Pharmacol; 2019 Aug; 392(8):1015-1029. PubMed ID: 31025144
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Cytochrome P450 2C19 enzyme, Cytochrome P450 2C9 enzyme, and Cytochrome P450 2D6 enzyme allelic variants and its possible effect on drug metabolism: A retrospective study.
    Naujokaitis D; Asmoniene V; Kadusevicius E
    Medicine (Baltimore); 2021 Mar; 100(11):e24545. PubMed ID: 33725937
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Allele and genotype frequencies of CYP2C9, CYP2C19 and CYP2D6 in an Italian population.
    Scordo MG; Caputi AP; D'Arrigo C; Fava G; Spina E
    Pharmacol Res; 2004 Aug; 50(2):195-200. PubMed ID: 15177309
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Expression, purification, biochemical characterization, and comparative function of human cytochrome P450 2D6.1, 2D6.2, 2D6.10, and 2D6.17 allelic isoforms.
    Yu A; Kneller BM; Rettie AE; Haining RL
    J Pharmacol Exp Ther; 2002 Dec; 303(3):1291-300. PubMed ID: 12438554
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Genetic polymorphisms of cytochromes P450: CYP2C9, CYP2C19, and CYP2D6 in Croatian population.
    Bozina N; Granić P; Lalić Z; Tramisak I; Lovrić M; Stavljenić-Rukavina A
    Croat Med J; 2003 Aug; 44(4):425-8. PubMed ID: 12950145
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The effect of dimethyl sulfoxide on the function of cytochrome P450 2D6 in HepG2 cells upon the co-expression with NADPH-cytochrome P450 reductase.
    Narimatsu S; Takatsu N; Yamano S; Inoue Y; Hanioka N; Kiryu K; Naito S; Gonzalez FJ; Yamamoto S
    Chem Biol Interact; 2006 Jan; 159(1):47-57. PubMed ID: 16214121
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The Molecular and Enzyme Kinetic Basis for Altered Activity of Three Cytochrome P450 2C19 Variants Found in the Chinese Population.
    Dong AN; Ahemad N; Pan Y; Palanisamy UD; Yiap BC; Ong CE
    Curr Mol Pharmacol; 2020; 13(3):233-244. PubMed ID: 31713493
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Recombinant production of human microsomal cytochrome P450 2D6 in the methylotrophic yeast Pichia pastoris.
    Dietrich M; Grundmann L; Kurr K; Valinotto L; Saussele T; Schmid RD; Lange S
    Chembiochem; 2005 Nov; 6(11):2014-22. PubMed ID: 16222729
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Cytochrome P450 genotypes are not associated with refractoriness to antipsychotic treatment.
    van de Bilt MT; Prado CM; Ojopi EP; Sousa RT; Loch AA; Zanetti MV; Talib LL; Gattaz WF
    Schizophr Res; 2015 Oct; 168(1-2):587-8. PubMed ID: 26298540
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Defining screening panel of functional variants of CYP1A1, CYP2C9, CYP2C19, CYP2D6, and CYP3A4 genes in Serbian population.
    Skadrić I; Stojković O
    Int J Legal Med; 2020 Mar; 134(2):433-439. PubMed ID: 31858263
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Functional characterization of 50 CYP2D6 allelic variants by assessing primaquine 5-hydroxylation.
    Saito T; Gutiérrez Rico EM; Kikuchi A; Kaneko A; Kumondai M; Akai F; Saigusa D; Oda A; Hirasawa N; Hiratsuka M
    Drug Metab Pharmacokinet; 2018 Dec; 33(6):250-257. PubMed ID: 30366777
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Heterologous expression of human cytochrome P450 (CYP) 2C19 in Escherichia coli and establishment of RP-HPLC method to serve as activity marker.
    Pan Y; Mak JW; Ong CE
    Biomed Chromatogr; 2013 Jul; 27(7):859-65. PubMed ID: 23386533
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Metabolism of testosterone and progesterone by cytochrome P450 2C19 allelic variants.
    Takeji S; Okada M; Hayashi S; Kanamaru K; Uno Y; Imaishi H; Uno T
    Biopharm Drug Dispos; 2023 Dec; 44(6):420-430. PubMed ID: 37815926
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Pharmacogenetics of P450 oxidoreductase: effect of sequence variants on activities of CYP1A2 and CYP2C19.
    Agrawal V; Huang N; Miller WL
    Pharmacogenet Genomics; 2008 Jul; 18(7):569-76. PubMed ID: 18551037
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Molecular modelling of cytochrome P4502D6 (CYP2D6) based on an alignment with CYP102: structural studies on specific CYP2D6 substrate metabolism.
    Lewis DF; Eddershaw PJ; Goldfarb PS; Tarbit MH
    Xenobiotica; 1997 Apr; 27(4):319-39. PubMed ID: 9149373
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Heterologous expression of human cytochromes P450 2D6 and CYP3A4 in Escherichia coli and their functional characterization.
    Pan Y; Abd-Rashid BA; Ismail Z; Ismail R; Mak JW; Ong CE
    Protein J; 2011 Dec; 30(8):581-91. PubMed ID: 22001938
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Role of P34S, G169R, R296C, and S486T Substitutions in Ligand Access and Catalysis for Cytochrome P450 2D6 Allelic Variants CYP2D6*14A and CYP2D6*14B.
    Dong AN; Ahemad N; Pan Y; Palanisamy UD; Yiap BC; Ong CE
    Drug Metab Bioanal Lett; 2022; 15(1):51-63. PubMed ID: 35049443
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.