BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

523 related articles for article (PubMed ID: 29531057)

  • 1. Lateral cerebellum is preferentially sensitive to high sonic hedgehog signaling and medulloblastoma formation.
    Tan IL; Wojcinski A; Rallapalli H; Lao Z; Sanghrajka RM; Stephen D; Volkova E; Korshunov A; Remke M; Taylor MD; Turnbull DH; Joyner AL
    Proc Natl Acad Sci U S A; 2018 Mar; 115(13):3392-3397. PubMed ID: 29531057
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Hedgehog pathway permissive conditions allow generation of immortal cell lines from granule cells derived from cancerous and non-cancerous cerebellum.
    Heil C
    Open Biol; 2019 Jan; 9(1):180145. PubMed ID: 30958113
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Genetic ablation of Gpr37l1 delays tumor occurrence in Ptch1
    Di Pietro C; La Sala G; Matteoni R; Marazziti D; Tocchini-Valentini GP
    Exp Neurol; 2019 Feb; 312():33-42. PubMed ID: 30452905
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Ex vivo miRNome analysis in Ptch1+/- cerebellum granule cells reveals a subset of miRNAs involved in radiation-induced medulloblastoma.
    Tanno B; Babini G; Leonardi S; Giardullo P; De Stefano I; Pasquali E; Ottolenghi A; Atkinson MJ; Saran A; Mancuso M
    Oncotarget; 2016 Oct; 7(42):68253-68269. PubMed ID: 27626168
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Pik3ca mutations significantly enhance the growth of SHH medulloblastoma and lead to metastatic tumour growth in a novel mouse model.
    Niesen J; Ohli J; Sedlacik J; Dührsen L; Hellwig M; Spohn M; Holsten T; Schüller U
    Cancer Lett; 2020 May; 477():10-18. PubMed ID: 32112900
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Transcriptional repressor REST drives lineage stage-specific chromatin compaction at
    Dobson THW; Tao RH; Swaminathan J; Maegawa S; Shaik S; Bravo-Alegria J; Sharma A; Kennis B; Yang Y; Callegari K; Haltom AR; Taylor P; Kogiso M; Qi L; Khatua S; Goldman S; Lulla RR; Fangusaro J; MacDonald TJ; Li XN; Hawkins C; Rajaram V; Gopalakrishnan V
    Sci Signal; 2019 Jan; 12(565):. PubMed ID: 30670636
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Disruption of the ciliary GTPase Arl13b suppresses Sonic hedgehog overactivation and inhibits medulloblastoma formation.
    Bay SN; Long AB; Caspary T
    Proc Natl Acad Sci U S A; 2018 Feb; 115(7):1570-1575. PubMed ID: 29378965
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Expression of Sonic hedgehog during cell proliferation in the human cerebellum.
    Haldipur P; Bharti U; Govindan S; Sarkar C; Iyengar S; Gressens P; Mani S
    Stem Cells Dev; 2012 May; 21(7):1059-68. PubMed ID: 21732818
    [TBL] [Abstract][Full Text] [Related]  

  • 9. PTCH1-mutant human cerebellar organoids exhibit altered neural development and recapitulate early medulloblastoma tumorigenesis.
    van Essen MJ; Apsley EJ; Riepsaame J; Xu R; Northcott PA; Cowley SA; Jacob J; Becker EBE
    Dis Model Mech; 2024 Feb; 17(2):. PubMed ID: 38411252
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Thickened area of external granular layer and Ki-67 positive focus are early events of medulloblastoma in Ptch1⁺/⁻ mice.
    Matsuo S; Takahashi M; Inoue K; Tamura K; Irie K; Kodama Y; Nishikawa A; Yoshida M
    Exp Toxicol Pathol; 2013 Sep; 65(6):863-73. PubMed ID: 23369240
    [TBL] [Abstract][Full Text] [Related]  

  • 11. CAT3, a novel agent for medulloblastoma and glioblastoma treatment, inhibits tumor growth by disrupting the Hedgehog signaling pathway.
    Chen J; Lv H; Hu J; Ji M; Xue N; Li C; Ma S; Zhou Q; Lin B; Li Y; Yu S; Chen X
    Cancer Lett; 2016 Oct; 381(2):391-403. PubMed ID: 27495899
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The Shh receptor Boc promotes progression of early medulloblastoma to advanced tumors.
    Mille F; Tamayo-Orrego L; Lévesque M; Remke M; Korshunov A; Cardin J; Bouchard N; Izzi L; Kool M; Northcott PA; Taylor MD; Pfister SM; Charron F
    Dev Cell; 2014 Oct; 31(1):34-47. PubMed ID: 25263791
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Truncated BRPF1 Cooperates with Smoothened to Promote Adult Shh Medulloblastoma.
    Aiello G; Ballabio C; Ruggeri R; Fagnocchi L; Anderle M; Morassut I; Caron D; Garilli F; Gianno F; Giangaspero F; Piazza S; Romanel A; Zippo A; Tiberi L
    Cell Rep; 2019 Dec; 29(12):4036-4052.e10. PubMed ID: 31851932
    [TBL] [Abstract][Full Text] [Related]  

  • 14. YB-1 is elevated in medulloblastoma and drives proliferation in Sonic hedgehog-dependent cerebellar granule neuron progenitor cells and medulloblastoma cells.
    Dey A; Robitaille M; Remke M; Maier C; Malhotra A; Gregorieff A; Wrana JL; Taylor MD; Angers S; Kenney AM
    Oncogene; 2016 Aug; 35(32):4256-68. PubMed ID: 26725322
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Multifaceted Functions of Rab23 on Primary Cilium-Mediated and Hedgehog Signaling-Mediated Cerebellar Granule Cell Proliferation.
    Hor CHH; Lo JCW; Cham ALS; Leong WY; Goh ELK
    J Neurosci; 2021 Aug; 41(32):6850-6863. PubMed ID: 34210780
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Opposing Effects of CREBBP Mutations Govern the Phenotype of Rubinstein-Taybi Syndrome and Adult SHH Medulloblastoma.
    Merk DJ; Ohli J; Merk ND; Thatikonda V; Morrissy S; Schoof M; Schmid SN; Harrison L; Filser S; Ahlfeld J; Erkek S; Raithatha K; Andreska T; Weißhaar M; Launspach M; Neumann JE; Shakarami M; Plenker D; Marra MA; Li Y; Mungall AJ; Moore RA; Ma Y; Jones SJM; Lutz B; Ertl-Wagner B; Rossi A; Wagener R; Siebert R; Jung A; Eberhart CG; Lach B; Sendtner M; Pfister SM; Taylor MD; Chavez L; Kool M; Schüller U
    Dev Cell; 2018 Mar; 44(6):709-724.e6. PubMed ID: 29551561
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Genome sequencing of SHH medulloblastoma predicts genotype-related response to smoothened inhibition.
    Kool M; Jones DT; Jäger N; Northcott PA; Pugh TJ; Hovestadt V; Piro RM; Esparza LA; Markant SL; Remke M; Milde T; Bourdeaut F; Ryzhova M; Sturm D; Pfaff E; Stark S; Hutter S; Seker-Cin H; Johann P; Bender S; Schmidt C; Rausch T; Shih D; Reimand J; Sieber L; Wittmann A; Linke L; Witt H; Weber UD; Zapatka M; König R; Beroukhim R; Bergthold G; van Sluis P; Volckmann R; Koster J; Versteeg R; Schmidt S; Wolf S; Lawerenz C; Bartholomae CC; von Kalle C; Unterberg A; Herold-Mende C; Hofer S; Kulozik AE; von Deimling A; Scheurlen W; Felsberg J; Reifenberger G; Hasselblatt M; Crawford JR; Grant GA; Jabado N; Perry A; Cowdrey C; Croul S; Zadeh G; Korbel JO; Doz F; Delattre O; Bader GD; McCabe MG; Collins VP; Kieran MW; Cho YJ; Pomeroy SL; Witt O; Brors B; Taylor MD; Schüller U; Korshunov A; Eils R; Wechsler-Reya RJ; Lichter P; Pfister SM;
    Cancer Cell; 2014 Mar; 25(3):393-405. PubMed ID: 24651015
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Functional loss of a noncanonical BCOR-PRC1.1 complex accelerates SHH-driven medulloblastoma formation.
    Kutscher LM; Okonechnikov K; Batora NV; Clark J; Silva PBG; Vouri M; van Rijn S; Sieber L; Statz B; Gearhart MD; Shiraishi R; Mack N; Orr BA; Korshunov A; Gudenas BL; Smith KS; Mercier AL; Ayrault O; Hoshino M; Kool M; von Hoff K; Graf N; Fleischhack G; Bardwell VJ; Pfister SM; Northcott PA; Kawauchi D
    Genes Dev; 2020 Sep; 34(17-18):1161-1176. PubMed ID: 32820036
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Astrocytes Promote Medulloblastoma Progression through Hedgehog Secretion.
    Liu Y; Yuelling LW; Wang Y; Du F; Gordon RE; O'Brien JA; Ng JMY; Robins S; Lee EH; Liu H; Curran T; Yang ZJ
    Cancer Res; 2017 Dec; 77(23):6692-6703. PubMed ID: 28986380
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Canonical TGF-β pathway activity is a predictor of SHH-driven medulloblastoma survival and delineates putative precursors in cerebellar development.
    Aref D; Moffatt CJ; Agnihotri S; Ramaswamy V; Dubuc AM; Northcott PA; Taylor MD; Perry A; Olson JM; Eberhart CG; Croul SE
    Brain Pathol; 2013 Mar; 23(2):178-91. PubMed ID: 22966790
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 27.