These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

280 related articles for article (PubMed ID: 29533781)

  • 1. PKM1 Confers Metabolic Advantages and Promotes Cell-Autonomous Tumor Cell Growth.
    Morita M; Sato T; Nomura M; Sakamoto Y; Inoue Y; Tanaka R; Ito S; Kurosawa K; Yamaguchi K; Sugiura Y; Takizaki H; Yamashita Y; Katakura R; Sato I; Kawai M; Okada Y; Watanabe H; Kondoh G; Matsumoto S; Kishimoto A; Obata M; Matsumoto M; Fukuhara T; Motohashi H; Suematsu M; Komatsu M; Nakayama KI; Watanabe T; Soga T; Shima H; Maemondo M; Tanuma N
    Cancer Cell; 2018 Mar; 33(3):355-367.e7. PubMed ID: 29533781
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Organ-Specific MicroRNAs (
    Taniguchi K; Sugito N; Shinohara H; Kuranaga Y; Inomata Y; Komura K; Uchiyama K; Akao Y
    Int J Mol Sci; 2018 Apr; 19(5):. PubMed ID: 29695138
    [TBL] [Abstract][Full Text] [Related]  

  • 3. SAM68 promotes tumorigenesis in lung adenocarcinoma by regulating metabolic conversion via PKM alternative splicing.
    Zhu S; Chen W; Wang J; Qi L; Pan H; Feng Z; Tian D
    Theranostics; 2021; 11(7):3359-3375. PubMed ID: 33537092
    [No Abstract]   [Full Text] [Related]  

  • 4. Dietary-phytochemical mediated reversion of cancer-specific splicing inhibits Warburg effect in head and neck cancer.
    Yadav S; Bhagat SD; Gupta A; Samaiya A; Srivastava A; Shukla S
    BMC Cancer; 2019 Nov; 19(1):1031. PubMed ID: 31675998
    [TBL] [Abstract][Full Text] [Related]  

  • 5. MicroRNA-124 inhibits cancer cell growth through PTB1/PKM1/PKM2 feedback cascade in colorectal cancer.
    Taniguchi K; Sugito N; Kumazaki M; Shinohara H; Yamada N; Nakagawa Y; Ito Y; Otsuki Y; Uno B; Uchiyama K; Akao Y
    Cancer Lett; 2015 Jul; 363(1):17-27. PubMed ID: 25818238
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Germline loss of PKM2 promotes metabolic distress and hepatocellular carcinoma.
    Dayton TL; Gocheva V; Miller KM; Israelsen WJ; Bhutkar A; Clish CB; Davidson SM; Luengo A; Bronson RT; Jacks T; Vander Heiden MG
    Genes Dev; 2016 May; 30(9):1020-33. PubMed ID: 27125672
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Preventing pyruvate kinase muscle expression in Chinese hamster ovary cells curbs lactogenic behavior by altering glycolysis, gating pyruvate generation, and increasing pyruvate flux into the TCA cycle.
    Tang D; Sandoval W; Liu P; Lam C; Snedecor B; Misaghi S
    Biotechnol Prog; 2021 Sep; 37(5):e3193. PubMed ID: 34288605
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Pyruvate kinase M knockdown-induced signaling via AMP-activated protein kinase promotes mitochondrial biogenesis, autophagy, and cancer cell survival.
    Prakasam G; Singh RK; Iqbal MA; Saini SK; Tiku AB; Bamezai RNK
    J Biol Chem; 2017 Sep; 292(37):15561-15576. PubMed ID: 28778925
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Enhanced expression of the M2 isoform of pyruvate kinase is involved in gastric cancer development by regulating cancer-specific metabolism.
    Shiroki T; Yokoyama M; Tanuma N; Maejima R; Tamai K; Yamaguchi K; Oikawa T; Noguchi T; Miura K; Fujiya T; Shima H; Sato I; Murata-Kamiya N; Hatakeyama M; Iijima K; Shimosegawa T; Satoh K
    Cancer Sci; 2017 May; 108(5):931-940. PubMed ID: 28235245
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Organ-specific PTB1-associated microRNAs determine expression of pyruvate kinase isoforms.
    Taniguchi K; Ito Y; Sugito N; Kumazaki M; Shinohara H; Yamada N; Nakagawa Y; Sugiyama T; Futamura M; Otsuki Y; Yoshida K; Uchiyama K; Akao Y
    Sci Rep; 2015 Feb; 5():8647. PubMed ID: 25721733
    [TBL] [Abstract][Full Text] [Related]  

  • 11. PKM2 phosphorylates MLC2 and regulates cytokinesis of tumour cells.
    Jiang Y; Wang Y; Wang T; Hawke DH; Zheng Y; Li X; Zhou Q; Majumder S; Bi E; Liu DX; Huang S; Lu Z
    Nat Commun; 2014 Nov; 5():5566. PubMed ID: 25412762
    [TBL] [Abstract][Full Text] [Related]  

  • 12. No evidence for a shift in pyruvate kinase PKM1 to PKM2 expression during tumorigenesis.
    Bluemlein K; GrĂ¼ning NM; Feichtinger RG; Lehrach H; Kofler B; Ralser M
    Oncotarget; 2011 May; 2(5):393-400. PubMed ID: 21789790
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Pyruvate kinase type M2 contributes to the development of pancreatic ductal adenocarcinoma by regulating the production of metabolites and reactive oxygen species.
    Yokoyama M; Tanuma N; Shibuya R; Shiroki T; Abue M; Yamamoto K; Miura K; Yamaguchi K; Sato I; Tamai K; Satoh K
    Int J Oncol; 2018 Mar; 52(3):881-891. PubMed ID: 29393401
    [TBL] [Abstract][Full Text] [Related]  

  • 14. PKM2, cancer metabolism, and the road ahead.
    Dayton TL; Jacks T; Vander Heiden MG
    EMBO Rep; 2016 Dec; 17(12):1721-1730. PubMed ID: 27856534
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Role of isoenzyme M2 of pyruvate kinase in urothelial tumorigenesis.
    Zhou H; Wang X; Mo L; Liu Y; He F; Zhang F; Huang KH; Wu XR
    Oncotarget; 2016 Apr; 7(17):23947-60. PubMed ID: 26992222
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The ubiquitin ligase KBTBD8 regulates PKM1 levels via Erk1/2 and Aurora A to ensure oocyte quality.
    Li YR; Peng RR; Gao WY; Liu P; Chen LJ; Zhang XL; Zhang NN; Wang Y; Du L; Zhu FY; Wang LL; Li CR; Zeng WT; Li JM; Hu F; Zhang D; Yang ZX
    Aging (Albany NY); 2019 Feb; 11(4):1110-1128. PubMed ID: 30786262
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Anti-cancer fatty-acid derivative induces autophagic cell death through modulation of PKM isoform expression profile mediated by bcr-abl in chronic myeloid leukemia.
    Shinohara H; Taniguchi K; Kumazaki M; Yamada N; Ito Y; Otsuki Y; Uno B; Hayakawa F; Minami Y; Naoe T; Akao Y
    Cancer Lett; 2015 Apr; 360(1):28-38. PubMed ID: 25644089
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Isoform switch of pyruvate kinase M1 indeed occurs but not to pyruvate kinase M2 in human tumorigenesis.
    Zhan C; Yan L; Wang L; Ma J; Jiang W; Zhang Y; Shi Y; Wang Q
    PLoS One; 2015; 10(3):e0118663. PubMed ID: 25738776
    [TBL] [Abstract][Full Text] [Related]  

  • 19. PKM1 is involved in resistance to anti-cancer drugs.
    Taniguchi K; Sakai M; Sugito N; Kuranaga Y; Kumazaki M; Shinohara H; Ueda H; Futamura M; Yoshida K; Uchiyama K; Akao Y
    Biochem Biophys Res Commun; 2016 Apr; 473(1):174-180. PubMed ID: 27012213
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The cysteine residue at 424th of pyruvate kinase M2 is crucial for tetramerization and responsiveness to oxidative stress.
    Masaki S; Hashimoto K; Kihara D; Tsuzuki C; Kataoka N; Suzuki K
    Biochem Biophys Res Commun; 2020 Jun; 526(4):973-977. PubMed ID: 32295714
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.