BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

141 related articles for article (PubMed ID: 29536773)

  • 21. Discovery of N6-phenyl-1H-pyrazolo[3,4-d]pyrimidine-3,6-diamine derivatives as novel CK1 inhibitors using common-feature pharmacophore model based virtual screening and hit-to-lead optimization.
    Yang LL; Li GB; Yan HX; Sun QZ; Ma S; Ji P; Wang ZR; Feng S; Zou J; Yang SY
    Eur J Med Chem; 2012 Oct; 56():30-8. PubMed ID: 22944772
    [TBL] [Abstract][Full Text] [Related]  

  • 22. [Mitochondrial enzyme ABAD and its role in the development and treatment of Alzheimer's disease].
    Benek O; Musílek K; Kuca K
    Ceska Slov Farm; 2012 Aug; 61(4):144-9. PubMed ID: 23251955
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Determination of small molecule ABAD inhibitors crossing blood-brain barrier and pharmacokinetics.
    Vangavaragu JR; Valasani KR; Fang D; Williams TD; Yan SS
    J Alzheimers Dis; 2014; 42(1):333-44. PubMed ID: 24858403
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Novel Benzothiazole-based Ureas as 17β-HSD10 Inhibitors, A Potential Alzheimer's Disease Treatment.
    Aitken L; Benek O; McKelvie BE; Hughes RE; Hroch L; Schmidt M; Major LL; Vinklarova L; Kuca K; Smith TK; Musilek K; Gunn-Moore FJ
    Molecules; 2019 Jul; 24(15):. PubMed ID: 31362457
    [No Abstract]   [Full Text] [Related]  

  • 25. In silico-designed novel non-peptidic ABAD L
    Viswanath ANI; Kim T; Jung SY; Lim SM; Pae AN
    Chem Biol Drug Des; 2017 Dec; 90(6):1041-1055. PubMed ID: 28660722
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Cytoprotective role of mitochondrial amyloid beta peptide-binding alcohol dehydrogenase against a cytotoxic aldehyde.
    Murakami Y; Ohsawa I; Kasahara T; Ohta S
    Neurobiol Aging; 2009 Feb; 30(2):325-9. PubMed ID: 17707551
    [TBL] [Abstract][Full Text] [Related]  

  • 27. The role of the casein kinase 1 (CK1) family in different signaling pathways linked to cancer development.
    Knippschild U; Wolff S; Giamas G; Brockschmidt C; Wittau M; Würl PU; Eismann T; Stöter M
    Onkologie; 2005 Oct; 28(10):508-14. PubMed ID: 16186692
    [TBL] [Abstract][Full Text] [Related]  

  • 28. The protein kinase CK1: Inhibition, activation, and possible allosteric modulation.
    Sunkari YK; Meijer L; Flajolet M
    Front Mol Biosci; 2022; 9():916232. PubMed ID: 36090057
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Inhibitors of casein kinase 1 block the growth of Leishmania major promastigotes in vitro.
    Allocco JJ; Donald R; Zhong T; Lee A; Tang YS; Hendrickson RC; Liberator P; Nare B
    Int J Parasitol; 2006 Oct; 36(12):1249-59. PubMed ID: 16890941
    [TBL] [Abstract][Full Text] [Related]  

  • 30. ABAD enhances Abeta-induced cell stress via mitochondrial dysfunction.
    Takuma K; Yao J; Huang J; Xu H; Chen X; Luddy J; Trillat AC; Stern DM; Arancio O; Yan SS
    FASEB J; 2005 Apr; 19(6):597-8. PubMed ID: 15665036
    [TBL] [Abstract][Full Text] [Related]  

  • 31. CK1 delta inhibition: an emerging strategy to combat neurodegenerative diseases.
    Varano F; Catarzi D; Calenda S; Vigiani E; Colotta V
    Future Med Chem; 2022 Aug; 14(15):1111-1113. PubMed ID: 35801420
    [No Abstract]   [Full Text] [Related]  

  • 32. Identification of novel protein kinase CK1 delta (CK1delta) inhibitors through structure-based virtual screening.
    Cozza G; Gianoncelli A; Montopoli M; Caparrotta L; Venerando A; Meggio F; Pinna LA; Zagotto G; Moro S
    Bioorg Med Chem Lett; 2008 Oct; 18(20):5672-5. PubMed ID: 18799313
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Structure-based design and synthesis of benzothiazole phosphonate analogues with inhibitors of human ABAD-Aβ for treatment of Alzheimer's disease.
    Valasani KR; Hu G; Chaney MO; Yan SS
    Chem Biol Drug Des; 2013 Feb; 81(2):238-49. PubMed ID: 23039767
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Mitochondrial β-amyloid in Alzheimer's disease.
    Borger E; Aitken L; Muirhead KE; Allen ZE; Ainge JA; Conway SJ; Gunn-Moore FJ
    Biochem Soc Trans; 2011 Aug; 39(4):868-73. PubMed ID: 21787315
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Molecular dynamics simulations of the amyloid-beta binding alcohol dehydrogenase (ABAD) enzyme.
    Marques AT; Fernandes PA; Ramos MJ
    Bioorg Med Chem; 2008 Nov; 16(21):9511-8. PubMed ID: 18835182
    [TBL] [Abstract][Full Text] [Related]  

  • 36. 2-Phenylamino-6-cyano-1H-benzimidazole-based isoform selective casein kinase 1 gamma (CK1γ) inhibitors.
    Hua Z; Huang X; Bregman H; Chakka N; DiMauro EF; Doherty EM; Goldstein J; Gunaydin H; Huang H; Mercede S; Newcomb J; Patel VF; Turci SM; Yan J; Wilson C; Martin MW
    Bioorg Med Chem Lett; 2012 Sep; 22(17):5392-5. PubMed ID: 22877629
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Characterization of two T. gondii CK1 isoforms.
    Donald RG; Zhong T; Meijer L; Liberator PA
    Mol Biochem Parasitol; 2005 May; 141(1):15-27. PubMed ID: 15811523
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Synthesis and kinase inhibitory activity of novel substituted indigoids.
    Beauchard A; Laborie H; Rouillard H; Lozach O; Ferandin Y; Le Guével R; Guguen-Guillouzo C; Meijer L; Besson T; Thiéry V
    Bioorg Med Chem; 2009 Sep; 17(17):6257-63. PubMed ID: 19665384
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Targeting Casein Kinase 1 (CK1) in Hematological Cancers.
    Janovská P; Normant E; Miskin H; Bryja V
    Int J Mol Sci; 2020 Nov; 21(23):. PubMed ID: 33261128
    [TBL] [Abstract][Full Text] [Related]  

  • 40. 6-benzothiazolyl ureas, thioureas and guanidines are potent inhibitors of ABAD/17β-HSD10 and potential drugs for Alzheimer's disease treatment: Design, synthesis and in vitro evaluation.
    Benek O; Hroch L; Aitken L; Dolezal R; Guest P; Benkova M; Soukup O; Musil K; Kuca K; Smith TK; Gunn-Moore F; Musilek K
    Med Chem; 2017 Jan; ():. PubMed ID: 28067167
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 8.