272 related articles for article (PubMed ID: 29537987)
1. Hedgehog pathway and smoothened inhibitors in cancer therapies.
Chahal KK; Parle M; Abagyan R
Anticancer Drugs; 2018 Jun; 29(5):387-401. PubMed ID: 29537987
[TBL] [Abstract][Full Text] [Related]
2. Overcoming the emerging drug resistance of smoothened: an overview of small-molecule SMO antagonists with antiresistance activity.
Zhang H; Sun Z; Liu Z; Song C
Future Med Chem; 2018 Dec; 10(24):2855-2875. PubMed ID: 30557039
[TBL] [Abstract][Full Text] [Related]
3. Current trends in Hedgehog signaling pathway inhibition by small molecules.
Ghirga F; Mori M; Infante P
Bioorg Med Chem Lett; 2018 Oct; 28(19):3131-3140. PubMed ID: 30177379
[TBL] [Abstract][Full Text] [Related]
4. CDK7 inhibition suppresses aberrant hedgehog pathway and overcomes resistance to smoothened antagonists.
Liu F; Jiang W; Sui Y; Meng W; Hou L; Li T; Li M; Zhang L; Mo J; Wang J; Zhao Y; Zhang L; Ma J; Tang Y
Proc Natl Acad Sci U S A; 2019 Jun; 116(26):12986-12995. PubMed ID: 31182587
[TBL] [Abstract][Full Text] [Related]
5. Scaffold hopping approach to a new series of smoothened antagonists.
Lu W; Geng D; Sun Z; Yang Z; Ma H; Zheng J; Zhang X
Bioorg Med Chem Lett; 2014 May; 24(10):2300-4. PubMed ID: 24726807
[TBL] [Abstract][Full Text] [Related]
6. Hedgehog Signaling: From Basic Biology to Cancer Therapy.
Wu F; Zhang Y; Sun B; McMahon AP; Wang Y
Cell Chem Biol; 2017 Mar; 24(3):252-280. PubMed ID: 28286127
[TBL] [Abstract][Full Text] [Related]
7. Inhibition of Hedgehog-dependent tumors and cancer stem cells by a newly identified naturally occurring chemotype.
Infante P; Alfonsi R; Ingallina C; Quaglio D; Ghirga F; D'Acquarica I; Bernardi F; Di Magno L; Canettieri G; Screpanti I; Gulino A; Botta B; Mori M; Di Marcotullio L
Cell Death Dis; 2016 Sep; 7(9):e2376. PubMed ID: 27899820
[TBL] [Abstract][Full Text] [Related]
8. Novel-smoothened inhibitors for therapeutic targeting of naïve and drug-resistant hedgehog pathway-driven cancers.
Li QR; Zhao H; Zhang XS; Lang H; Yu K
Acta Pharmacol Sin; 2019 Feb; 40(2):257-267. PubMed ID: 29777201
[TBL] [Abstract][Full Text] [Related]
9. The Role of Smoothened in Cancer.
Jeng KS; Sheen IS; Leu CM; Tseng PH; Chang CF
Int J Mol Sci; 2020 Sep; 21(18):. PubMed ID: 32962123
[TBL] [Abstract][Full Text] [Related]
10. Crosstalk between hedgehog and other signaling pathways as a basis for combination therapies in cancer.
Brechbiel J; Miller-Moslin K; Adjei AA
Cancer Treat Rev; 2014 Jul; 40(6):750-9. PubMed ID: 24613036
[TBL] [Abstract][Full Text] [Related]
11. Discovery of Hedgehog Antagonists for Cancer Therapy.
Khatra H; Bose C; Sinha S
Curr Med Chem; 2017; 24(19):2033-2058. PubMed ID: 28302010
[TBL] [Abstract][Full Text] [Related]
12. Strategies to target the Hedgehog signaling pathway for cancer therapy.
Xin M; Ji X; De La Cruz LK; Thareja S; Wang B
Med Res Rev; 2018 May; 38(3):870-913. PubMed ID: 29315702
[TBL] [Abstract][Full Text] [Related]
13. Molecular Modelling of Berberine Derivatives as Inhibitors of Human Smoothened Receptor and Hedgehog Signalling Pathway Using a Newly Developed Algorithm on Anti-Cancer Drugs.
Kaboli PJ; Bazrafkan M; Ismail P; Ling KH
Recent Pat Anticancer Drug Discov; 2017 Nov; 12(4):384-400. PubMed ID: 28969581
[TBL] [Abstract][Full Text] [Related]
14. Evaluation of WO2014207069 A1: Multitarget Hedgehog pathway inhibitors and uses thereof.
Manetti F; Petricci E
Expert Opin Ther Pat; 2016; 26(4):529-35. PubMed ID: 26666870
[TBL] [Abstract][Full Text] [Related]
15. Posaconazole, a Second-Generation Triazole Antifungal Drug, Inhibits the Hedgehog Signaling Pathway and Progression of Basal Cell Carcinoma.
Chen B; Trang V; Lee A; Williams NS; Wilson AN; Epstein EH; Tang JY; Kim J
Mol Cancer Ther; 2016 May; 15(5):866-76. PubMed ID: 26823493
[TBL] [Abstract][Full Text] [Related]
16. Discovery of [1,2,4]triazolo[4,3-a]pyridines as potent Smoothened inhibitors targeting the Hedgehog pathway with improved antitumor activity in vivo.
Tian N; Wu H; Zhang H; Yang D; Lv L; Yang Z; Zhang T; Quan D; Zhou L; Xie Y; Xu Y; Wei N; Zhang J; Chen M; Schmitz JC; Tian Y; Wu S
Bioorg Med Chem; 2020 Aug; 28(16):115584. PubMed ID: 32690258
[TBL] [Abstract][Full Text] [Related]
17. ABT-199 inhibits Hedgehog pathway by acting as a competitive inhibitor of oxysterol, rather as a BH3 mimetic.
Wang J; Zhang Y; Huang WJ; Yang J; Tang WG; Huang TM; Tan WF
Acta Pharmacol Sin; 2021 Jun; 42(6):1005-1013. PubMed ID: 32855528
[TBL] [Abstract][Full Text] [Related]
18. Hedgehog signaling pathway inhibitors: an updated patent review (2015-present).
Quaglio D; Infante P; Di Marcotullio L; Botta B; Mori M
Expert Opin Ther Pat; 2020 Apr; 30(4):235-250. PubMed ID: 32070165
[No Abstract] [Full Text] [Related]
19. Selective identification of hedgehog pathway antagonists by direct analysis of smoothened ciliary translocation.
Wang Y; Arvanites AC; Davidow L; Blanchard J; Lam K; Yoo JW; Coy S; Rubin LL; McMahon AP
ACS Chem Biol; 2012 Jun; 7(6):1040-8. PubMed ID: 22554036
[TBL] [Abstract][Full Text] [Related]
20. MRT-92 inhibits Hedgehog signaling by blocking overlapping binding sites in the transmembrane domain of the Smoothened receptor.
Hoch L; Faure H; Roudaut H; Schoenfelder A; Mann A; Girard N; Bihannic L; Ayrault O; Petricci E; Taddei M; Rognan D; Ruat M
FASEB J; 2015 May; 29(5):1817-29. PubMed ID: 25636740
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
