These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
3. Mechanism of gasdermin D recognition by inflammatory caspases and their inhibition by a gasdermin D-derived peptide inhibitor. Yang J; Liu Z; Wang C; Yang R; Rathkey JK; Pinkard OW; Shi W; Chen Y; Dubyak GR; Abbott DW; Xiao TS Proc Natl Acad Sci U S A; 2018 Jun; 115(26):6792-6797. PubMed ID: 29891674 [TBL] [Abstract][Full Text] [Related]
4. Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death. Shi J; Zhao Y; Wang K; Shi X; Wang Y; Huang H; Zhuang Y; Cai T; Wang F; Shao F Nature; 2015 Oct; 526(7575):660-5. PubMed ID: 26375003 [TBL] [Abstract][Full Text] [Related]
5. Pyroptosis in neutrophils: Multimodal integration of inflammasome and regulated cell death signaling pathways. Dubyak GR; Miller BA; Pearlman E Immunol Rev; 2023 Mar; 314(1):229-249. PubMed ID: 36656082 [TBL] [Abstract][Full Text] [Related]
6. Cathepsin G Inhibition by Serpinb1 and Serpinb6 Prevents Programmed Necrosis in Neutrophils and Monocytes and Reduces GSDMD-Driven Inflammation. Burgener SS; Leborgne NGF; Snipas SJ; Salvesen GS; Bird PI; Benarafa C Cell Rep; 2019 Jun; 27(12):3646-3656.e5. PubMed ID: 31216481 [TBL] [Abstract][Full Text] [Related]
7. N-GSDMD trafficking to neutrophil organelles facilitates IL-1β release independently of plasma membrane pores and pyroptosis. Karmakar M; Minns M; Greenberg EN; Diaz-Aponte J; Pestonjamasp K; Johnson JL; Rathkey JK; Abbott DW; Wang K; Shao F; Catz SD; Dubyak GR; Pearlman E Nat Commun; 2020 May; 11(1):2212. PubMed ID: 32371889 [TBL] [Abstract][Full Text] [Related]
8. Gasdermin D plays a vital role in the generation of neutrophil extracellular traps. Sollberger G; Choidas A; Burn GL; Habenberger P; Di Lucrezia R; Kordes S; Menninger S; Eickhoff J; Nussbaumer P; Klebl B; Krüger R; Herzig A; Zychlinsky A Sci Immunol; 2018 Aug; 3(26):. PubMed ID: 30143555 [TBL] [Abstract][Full Text] [Related]
9. Gasdermin D in pyroptosis. Burdette BE; Esparza AN; Zhu H; Wang S Acta Pharm Sin B; 2021 Sep; 11(9):2768-2782. PubMed ID: 34589396 [TBL] [Abstract][Full Text] [Related]
10. Gasdermin D is an executor of pyroptosis and required for interleukin-1β secretion. He WT; Wan H; Hu L; Chen P; Wang X; Huang Z; Yang ZH; Zhong CQ; Han J Cell Res; 2015 Dec; 25(12):1285-98. PubMed ID: 26611636 [TBL] [Abstract][Full Text] [Related]
11. Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores. Liu X; Zhang Z; Ruan J; Pan Y; Magupalli VG; Wu H; Lieberman J Nature; 2016 Jul; 535(7610):153-8. PubMed ID: 27383986 [TBL] [Abstract][Full Text] [Related]
12. A bacterial toxin co-opts caspase-3 to disable active gasdermin D and limit macrophage pyroptosis. Wright SS; Wang C; Ta A; Havira MS; Ruan J; Rathinam VA; Vanaja SK Cell Rep; 2024 Apr; 43(4):114004. PubMed ID: 38522070 [TBL] [Abstract][Full Text] [Related]
13. Caspase-1 cleaves Bid to release mitochondrial SMAC and drive secondary necrosis in the absence of GSDMD. Heilig R; Dilucca M; Boucher D; Chen KW; Hancz D; Demarco B; Shkarina K; Broz P Life Sci Alliance; 2020 Jun; 3(6):. PubMed ID: 32345661 [TBL] [Abstract][Full Text] [Related]
14. Mechanism and Regulation of Gasdermin-Mediated Cell Death. Xia S; Hollingsworth LR; Wu H Cold Spring Harb Perspect Biol; 2020 Mar; 12(3):. PubMed ID: 31451512 [TBL] [Abstract][Full Text] [Related]
15. Lipid Peroxidation Drives Gasdermin D-Mediated Pyroptosis in Lethal Polymicrobial Sepsis. Kang R; Zeng L; Zhu S; Xie Y; Liu J; Wen Q; Cao L; Xie M; Ran Q; Kroemer G; Wang H; Billiar TR; Jiang J; Tang D Cell Host Microbe; 2018 Jul; 24(1):97-108.e4. PubMed ID: 29937272 [TBL] [Abstract][Full Text] [Related]
16. Uncoupled pyroptosis and IL-1β secretion downstream of inflammasome signaling. Li Y; Jiang Q Front Immunol; 2023; 14():1128358. PubMed ID: 37090724 [TBL] [Abstract][Full Text] [Related]
17. Porcine Gasdermin D Is a Substrate of Caspase-1 and an Executioner of Pyroptosis. Song Y; Song J; Wang M; Wang J; Ma B; Zhang W Front Immunol; 2022; 13():828911. PubMed ID: 35359964 [TBL] [Abstract][Full Text] [Related]
18. Caspase-8-dependent gasdermin D cleavage promotes antimicrobial defense but confers susceptibility to TNF-induced lethality. Demarco B; Grayczyk JP; Bjanes E; Le Roy D; Tonnus W; Assenmacher CA; Radaelli E; Fettrelet T; Mack V; Linkermann A; Roger T; Brodsky IE; Chen KW; Broz P Sci Adv; 2020 Nov; 6(47):. PubMed ID: 33208362 [TBL] [Abstract][Full Text] [Related]
19. Gasdermin D Cleavage Assay Following Inflammasome Activation. Kamajaya LJ; Boucher D Methods Mol Biol; 2022; 2459():39-49. PubMed ID: 35212952 [TBL] [Abstract][Full Text] [Related]