These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

305 related articles for article (PubMed ID: 29540553)

  • 1. SIRT1 Deacetylates Tau and Reduces Pathogenic Tau Spread in a Mouse Model of Tauopathy.
    Min SW; Sohn PD; Li Y; Devidze N; Johnson JR; Krogan NJ; Masliah E; Mok SA; Gestwicki JE; Gan L
    J Neurosci; 2018 Apr; 38(15):3680-3688. PubMed ID: 29540553
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Acetylation of tau inhibits its degradation and contributes to tauopathy.
    Min SW; Cho SH; Zhou Y; Schroeder S; Haroutunian V; Seeley WW; Huang EJ; Shen Y; Masliah E; Mukherjee C; Meyers D; Cole PA; Ott M; Gan L
    Neuron; 2010 Sep; 67(6):953-66. PubMed ID: 20869593
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Acetylated tau inhibits chaperone-mediated autophagy and promotes tau pathology propagation in mice.
    Caballero B; Bourdenx M; Luengo E; Diaz A; Sohn PD; Chen X; Wang C; Juste YR; Wegmann S; Patel B; Young ZT; Kuo SY; Rodriguez-Navarro JA; Shao H; Lopez MG; Karch CM; Goate AM; Gestwicki JE; Hyman BT; Gan L; Cuervo AM
    Nat Commun; 2021 Apr; 12(1):2238. PubMed ID: 33854069
    [TBL] [Abstract][Full Text] [Related]  

  • 4. SIRT1 Deacetylates SC35 and Suppresses Its Function in Tau Exon 10 Inclusion.
    Yin X; Jiang X; Wang J; Qian S; Liu F; Qian W
    J Alzheimers Dis; 2018; 61(2):561-570. PubMed ID: 29226865
    [TBL] [Abstract][Full Text] [Related]  

  • 5. SIRT1 deficiency increases O-GlcNAcylation of tau, mediating synaptic tauopathy.
    Yin X; Li Y; Fan X; Huang F; Qiu Y; Zhao C; Zhou Z; Gu Q; Xia L; Bao J; Wang X; Liu F; Qian W
    Mol Psychiatry; 2022 Oct; 27(10):4323-4334. PubMed ID: 35879403
    [TBL] [Abstract][Full Text] [Related]  

  • 6. AMPK Ameliorates Tau Acetylation and Memory Impairment Through Sirt1.
    Wang L; Shi FX; Li N; Cao Y; Lei Y; Wang JZ; Tian Q; Zhou XW
    Mol Neurobiol; 2020 Dec; 57(12):5011-5025. PubMed ID: 32820462
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Hippocampal SIRT1 improves cognitive impairment by deacetylating tau protein in diabetic models.
    Shi N; Lin Y; Yan B; Jiao X; Ding X; Wu Y; Zhou C
    Eur J Pharmacol; 2022 Jan; 914():174666. PubMed ID: 34861210
    [TBL] [Abstract][Full Text] [Related]  

  • 8. An HDAC6-dependent surveillance mechanism suppresses tau-mediated neurodegeneration and cognitive decline.
    Trzeciakiewicz H; Ajit D; Tseng JH; Chen Y; Ajit A; Tabassum Z; Lobrovich R; Peterson C; Riddick NV; Itano MS; Tripathy A; Moy SS; Lee VMY; Trojanowski JQ; Irwin DJ; Cohen TJ
    Nat Commun; 2020 Nov; 11(1):5522. PubMed ID: 33139698
    [TBL] [Abstract][Full Text] [Related]  

  • 9. SIRT1 Regulates Tau Expression and Tau Synaptic Pathology.
    Yin X; Zhou Z; Qiu Y; Fan X; Zhao C; Bao J; Liu C; Liu F; Qian W
    J Alzheimers Dis; 2021; 84(2):895-904. PubMed ID: 34602486
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A unique tau conformation generated by an acetylation-mimic substitution modulates P301S-dependent tau pathology and hyperphosphorylation.
    Ajit D; Trzeciakiewicz H; Tseng JH; Wander CM; Chen Y; Ajit A; King DP; Cohen TJ
    J Biol Chem; 2019 Nov; 294(45):16698-16711. PubMed ID: 31543505
    [TBL] [Abstract][Full Text] [Related]  

  • 11. An acetylation-phosphorylation switch that regulates tau aggregation propensity and function.
    Carlomagno Y; Chung DC; Yue M; Castanedes-Casey M; Madden BJ; Dunmore J; Tong J; DeTure M; Dickson DW; Petrucelli L; Cook C
    J Biol Chem; 2017 Sep; 292(37):15277-15286. PubMed ID: 28760828
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Anti-acetylated-tau immunotherapy is neuroprotective in tauopathy and brain injury.
    Parra Bravo C; Krukowski K; Barker S; Wang C; Li Y; Fan L; Vázquez-Rosa E; Shin MK; Wong MY; McCullough LD; Kitagawa RS; Choi HA; Cacace A; Sinha SC; Pieper AA; Rosi S; Chen X; Gan L
    Mol Neurodegener; 2024 Jun; 19(1):51. PubMed ID: 38915105
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Critical role of acetylation in tau-mediated neurodegeneration and cognitive deficits.
    Min SW; Chen X; Tracy TE; Li Y; Zhou Y; Wang C; Shirakawa K; Minami SS; Defensor E; Mok SA; Sohn PD; Schilling B; Cong X; Ellerby L; Gibson BW; Johnson J; Krogan N; Shamloo M; Gestwicki J; Masliah E; Verdin E; Gan L
    Nat Med; 2015 Oct; 21(10):1154-62. PubMed ID: 26390242
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Sirt1 enhances tau exon 10 inclusion and improves spatial memory of Htau mice.
    Qian S; Gu J; Dai W; Jin N; Chu D; Huang Q; Liu F; Qian W
    Aging (Albany NY); 2018 Sep; 10(9):2498-2510. PubMed ID: 30243024
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Selective Disruption of Inhibitory Synapses Leading to Neuronal Hyperexcitability at an Early Stage of Tau Pathogenesis in a Mouse Model.
    Shimojo M; Takuwa H; Takado Y; Tokunaga M; Tsukamoto S; Minatohara K; Ono M; Seki C; Maeda J; Urushihata T; Minamihisamatsu T; Aoki I; Kawamura K; Zhang MR; Suhara T; Sahara N; Higuchi M
    J Neurosci; 2020 Apr; 40(17):3491-3501. PubMed ID: 32265258
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Hippocampal tauopathy in tau transgenic mice coincides with impaired hippocampus-dependent learning and memory, and attenuated late-phase long-term depression of synaptic transmission.
    Van der Jeugd A; Ahmed T; Burnouf S; Belarbi K; Hamdame M; Grosjean ME; Humez S; Balschun D; Blum D; Buée L; D'Hooge R
    Neurobiol Learn Mem; 2011 Mar; 95(3):296-304. PubMed ID: 21167950
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A novel transgenic mouse expressing double mutant tau driven by its natural promoter exhibits tauopathy characteristics.
    Rosenmann H; Grigoriadis N; Eldar-Levy H; Avital A; Rozenstein L; Touloumi O; Behar L; Ben-Hur T; Avraham Y; Berry E; Segal M; Ginzburg I; Abramsky O
    Exp Neurol; 2008 Jul; 212(1):71-84. PubMed ID: 18490011
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Argyrophilic grain disease differs from other tauopathies by lacking tau acetylation.
    Grinberg LT; Wang X; Wang C; Sohn PD; Theofilas P; Sidhu M; Arevalo JB; Heinsen H; Huang EJ; Rosen H; Miller BL; Gan L; Seeley WW
    Acta Neuropathol; 2013 Apr; 125(4):581-93. PubMed ID: 23371364
    [TBL] [Abstract][Full Text] [Related]  

  • 19. MK-8719, a Novel and Selective
    Wang X; Li W; Marcus J; Pearson M; Song L; Smith K; Terracina G; Lee J; Hong KK; Lu SX; Hyde L; Chen SC; Kinsley D; Melchor JP; Rubins DJ; Meng X; Hostetler E; Sur C; Zhang L; Schachter JB; Hess JF; Selnick HG; Vocadlo DJ; McEachern EJ; Uslaner JM; Duffy JL; Smith SM
    J Pharmacol Exp Ther; 2020 Aug; 374(2):252-263. PubMed ID: 32493725
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Acetylated tau in Alzheimer's disease: An instigator of synaptic dysfunction underlying memory loss: Increased levels of acetylated tau blocks the postsynaptic signaling required for plasticity and promotes memory deficits associated with tauopathy.
    Tracy TE; Gan L
    Bioessays; 2017 Apr; 39(4):. PubMed ID: 28083916
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.