BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

232 related articles for article (PubMed ID: 29540819)

  • 1. Inhibition of p70 S6 kinase activity by A77 1726 induces autophagy and enhances the degradation of superoxide dismutase 1 (SOD1) protein aggregates.
    Sun J; Mu Y; Jiang Y; Song R; Yi J; Zhou J; Sun J; Jiao X; Prinz RA; Li Y; Xu X
    Cell Death Dis; 2018 Mar; 9(3):407. PubMed ID: 29540819
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Inhibition of p70 S6 kinase (S6K1) activity by A77 1726, the active metabolite of leflunomide, induces autophagy through TAK1-mediated AMPK and JNK activation.
    Xu X; Sun J; Song R; Doscas ME; Williamson AJ; Zhou J; Sun J; Jiao X; Liu X; Li Y
    Oncotarget; 2017 May; 8(18):30438-30454. PubMed ID: 28389629
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Restriction of intracellular Salmonella typhimurium growth by the small-molecule autophagy inducer A77 1726 through the activation of the AMPK-ULK1 axis.
    Zhuang J; Ji X; Zhu Y; Liu W; Sun J; Jiao X; Xu X
    Vet Microbiol; 2021 Mar; 254():108982. PubMed ID: 33461007
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Inhibition of p70 S6 kinase (S6K1) activity by A77 1726 and its effect on cell proliferation and cell cycle progress.
    Doscas ME; Williamson AJ; Usha L; Bogachkov Y; Rao GS; Xiao F; Wang Y; Ruby C; Kaufman H; Zhou J; Williams JW; Li Y; Xu X
    Neoplasia; 2014 Oct; 16(10):824-34. PubMed ID: 25379019
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Inhibition of canine distemper virus replication by blocking pyrimidine nucleotide synthesis with A77 1726, the active metabolite of the anti-inflammatory drug leflunomide.
    Li Y; Yi L; Cheng S; Wang Y; Wang J; Sun J; Zhang Q; Xu X
    J Gen Virol; 2021 Mar; 102(3):. PubMed ID: 33416466
    [TBL] [Abstract][Full Text] [Related]  

  • 6. TGF-β-activated kinase 1 (TAK1) mediates cadmium-induced autophagy in osteoblasts via the AMPK / mTORC1 / ULK1 pathway.
    Ran D; Ma Y; Liu W; Luo T; Zheng J; Wang D; Song R; Zhao H; Zou H; Gu J; Yuan Y; Bian J; Liu Z
    Toxicology; 2020 Sep; 442():152538. PubMed ID: 32693121
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Leflunomide alleviates obesity via activation of the TAK1-AMPK pathway and induction of lipophagy.
    Ji X; Chen J; You C; Sun J; Xu X
    FASEB J; 2023 Nov; 37(11):e23227. PubMed ID: 37792678
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Aspirin inhibits mTOR signaling, activates AMP-activated protein kinase, and induces autophagy in colorectal cancer cells.
    Din FV; Valanciute A; Houde VP; Zibrova D; Green KA; Sakamoto K; Alessi DR; Dunlop MG
    Gastroenterology; 2012 Jun; 142(7):1504-15.e3. PubMed ID: 22406476
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Control of hyperglycemia in male mice by leflunomide: mechanisms of action.
    Chen J; Sun J; Doscas ME; Ye J; Williamson AJ; Li Y; Li Y; Prinz RA; Xu X
    J Endocrinol; 2018 Apr; 237(1):43-58. PubMed ID: 29496905
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Modulation of the IGF1R-MTOR pathway attenuates motor neuron toxicity of human ALS SOD1
    Granatiero V; Sayles NM; Savino AM; Konrad C; Kharas MG; Kawamata H; Manfredi G
    Autophagy; 2021 Dec; 17(12):4029-4042. PubMed ID: 33749521
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Digitoxin Suppresses Human Cytomegalovirus Replication via Na
    Mukhopadhyay R; Venkatadri R; Katsnelson J; Arav-Boger R
    J Virol; 2018 Mar; 92(6):. PubMed ID: 29321306
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Toll-like receptor signalling cross-activates the autophagic pathway to restrict Salmonella Typhimurium growth in macrophages.
    Liu W; Zhuang J; Jiang Y; Sun J; Prinz RA; Sun J; Jiao X; Xu X
    Cell Microbiol; 2019 Dec; 21(12):e13095. PubMed ID: 31392811
    [TBL] [Abstract][Full Text] [Related]  

  • 13. BL-918, a small-molecule activator of ULK1, induces cytoprotective autophagy for amyotrophic lateral sclerosis therapy.
    Liu W; Zhu SO; Guo YL; Tu LF; Zhen YQ; Zhao RY; Ou-Yang L; Kurihara H; He RR; Liu B
    Acta Pharmacol Sin; 2023 Mar; 44(3):524-537. PubMed ID: 36042292
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Activation of TGF-β-activated kinase 1 (TAK1) restricts Salmonella Typhimurium growth by inducing AMPK activation and autophagy.
    Liu W; Jiang Y; Sun J; Geng S; Pan Z; Prinz RA; Wang C; Sun J; Jiao X; Xu X
    Cell Death Dis; 2018 May; 9(5):570. PubMed ID: 29752434
    [TBL] [Abstract][Full Text] [Related]  

  • 15. [Effect of electroacupuncture on hepatocyte autophagy and oxidative stress in SAMP8 mice by regulating AMPK/mTOR/ULK1 signaling pathway].
    Yang YH; Tao CH; Pang F; Yang ZX; Zhu ZW; Guo X; Liao DM; Dai P; Tang CL
    Zhen Ci Yan Jiu; 2022 Jan; 47(1):7-14. PubMed ID: 35128864
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Inhibition of mitochondrial complex 1 by the S6K1 inhibitor PF-4708671 partly contributes to its glucose metabolic effects in muscle and liver cells.
    Shum M; Houde VP; Bellemare V; Junges Moreira R; Bellmann K; St-Pierre P; Viollet B; Foretz M; Marette A
    J Biol Chem; 2019 Aug; 294(32):12250-12260. PubMed ID: 31243102
    [TBL] [Abstract][Full Text] [Related]  

  • 17. hVps34 is a nutrient-regulated lipid kinase required for activation of p70 S6 kinase.
    Byfield MP; Murray JT; Backer JM
    J Biol Chem; 2005 Sep; 280(38):33076-82. PubMed ID: 16049009
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Peroxisome proliferator-activated receptor-gamma and retinoic acid X receptor alpha represses the TGFbeta1 gene via PTEN-mediated p70 ribosomal S6 kinase-1 inhibition: role for Zf9 dephosphorylation.
    Lee SJ; Yang EK; Kim SG
    Mol Pharmacol; 2006 Jul; 70(1):415-25. PubMed ID: 16611854
    [TBL] [Abstract][Full Text] [Related]  

  • 19. S6K1 inhibits HBV replication through inhibiting AMPK-ULK1 pathway and disrupting acetylation modification of H3K27.
    Wang Y; Han M; Liu S; Yuan X; Zhao J; Lu H; Han K; Liang P; Cheng J
    Life Sci; 2021 Jan; 265():118848. PubMed ID: 33278383
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Distinct roles for motor neuron autophagy early and late in the SOD1
    Rudnick ND; Griffey CJ; Guarnieri P; Gerbino V; Wang X; Piersaint JA; Tapia JC; Rich MM; Maniatis T
    Proc Natl Acad Sci U S A; 2017 Sep; 114(39):E8294-E8303. PubMed ID: 28904095
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.