These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

169 related articles for article (PubMed ID: 29545101)

  • 1. Structure-based design and structure-activity relationships of 1,2,3,4-tetrahydroisoquinoline derivatives as potential PDE4 inhibitors.
    Liao Y; Guo Y; Li S; Wang L; Tang Y; Li T; Chen W; Zhong G; Song G
    Bioorg Med Chem Lett; 2018 Apr; 28(7):1188-1193. PubMed ID: 29545101
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Design, synthesis and biological evaluation of novel tetrahydroisoquinoline derivatives as potential PDE4 inhibitors.
    Song G; Zhao D; Hu D; Li Y; Jin H; Cui Z
    Bioorg Med Chem Lett; 2015 Oct; 25(20):4610-4. PubMed ID: 26320621
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Rational design of conformationally constrained oxazolidinone-fused 1,2,3,4-tetrahydroisoquinoline derivatives as potential PDE4 inhibitors.
    Song G; Zhu X; Li J; Hu D; Zhao D; Liao Y; Lin J; Zhang LH; Cui ZN
    Bioorg Med Chem; 2017 Oct; 25(20):5709-5717. PubMed ID: 28888661
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Design, synthesis, and biological evaluation of tetrahydroisoquinolines derivatives as novel, selective PDE4 inhibitors for antipsoriasis treatment.
    Zhang R; Li H; Zhang X; Li J; Su H; Lu Q; Dong G; Dou H; Fan C; Gu Z; Mu Q; Tang W; Xu Y; Liu H
    Eur J Med Chem; 2021 Feb; 211():113004. PubMed ID: 33218684
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis and bioactivity of pyrazole and triazole derivatives as potential PDE4 inhibitors.
    Li YS; Tian H; Zhao DS; Hu DK; Liu XY; Jin HW; Song GP; Cui ZN
    Bioorg Med Chem Lett; 2016 Aug; 26(15):3632-5. PubMed ID: 27289320
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Discovery of novel inhibitors of phosphodiesterase 4 with 1-phenyl-3,4-dihydroisoquinoline scaffold: Structure-based drug design and fragment identification.
    Liao Y; Jia X; Tang Y; Li S; Zang Y; Wang L; Cui ZN; Song G
    Bioorg Med Chem Lett; 2019 Nov; 29(22):126720. PubMed ID: 31610942
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synthesis and bioactivity of phenyl substituted furan and oxazole carboxylic acid derivatives as potential PDE4 inhibitors.
    Lin Y; Ahmed W; He M; Xiang X; Tang R; Cui ZN
    Eur J Med Chem; 2020 Dec; 207():112795. PubMed ID: 33002845
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Design and synthesis of 4,5,6,7-tetrahydro-1H-1,2-diazepin-7-one derivatives as a new series of Phosphodiesterase 4 (PDE4) inhibitors.
    Guariento S; Karawajczyk A; Bull JA; Marchini G; Bielska M; Iwanowa X; Bruno O; Fossa P; Giordanetto F
    Bioorg Med Chem Lett; 2017 Jan; 27(1):24-29. PubMed ID: 27890378
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Novel N-indolylmethyl substituted olanzapine derivatives: their design, synthesis and evaluation as PDE4B inhibitors.
    Gorja DR; Mukherjee S; Meda CL; Deora GS; Kumar KL; Jain A; Chaudhari GH; Chennubhotla KS; Banote RK; Kulkarni P; Parsa KV; Mukkanti K; Pal M
    Org Biomol Chem; 2013 Apr; 11(13):2075-9. PubMed ID: 23436140
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Tetrahydroquinoline and tetrahydroisoquinoline derivatives as potential selective PDE4B inhibitors.
    Li YS; Liu XY; Zhao DS; Liao YX; Zhang LH; Zhang FZ; Song GP; Cui ZN
    Bioorg Med Chem Lett; 2018 Oct; 28(19):3271-3275. PubMed ID: 30131242
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis and bioactivity of 3,5-dimethylpyrazole derivatives as potential PDE4 inhibitors.
    Hu DK; Zhao DS; He M; Jin HW; Tang YM; Zhang LH; Song GP; Cui ZN
    Bioorg Med Chem Lett; 2018 Oct; 28(19):3276-3280. PubMed ID: 30131240
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis, antitumor activity, and molecular docking study of 2-cyclopentyloxyanisole derivatives: mechanistic study of enzyme inhibition.
    El-Husseiny WM; El-Sayed MA; El-Azab AS; AlSaif NA; Alanazi MM; Abdel-Aziz AA
    J Enzyme Inhib Med Chem; 2020 Dec; 35(1):744-758. PubMed ID: 32183576
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Design, synthesis, and biological evaluation of novel catecholopyrimidine based PDE4 inhibitor for the treatment of atopic dermatitis.
    Purushothaman B; Arumugam P; Kulsi G; Song JM
    Eur J Med Chem; 2018 Feb; 145():673-690. PubMed ID: 29353721
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Design, synthesis and biological evaluation of 2,4-disubstituted oxazole derivatives as potential PDE4 inhibitors.
    Li YS; Hu DK; Zhao DS; Liu XY; Jin HW; Song GP; Cui ZN; Zhang LH
    Bioorg Med Chem; 2017 Mar; 25(6):1852-1859. PubMed ID: 28196708
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Novel quinazolin-4(3H)-one/Schiff base hybrids as antiproliferative and phosphodiesterase 4 inhibitors: design, synthesis, and docking studies.
    Abdel-Rahman HM; Abdel-Aziz M; Canzoneri JC; Gary BD; Piazza GA
    Arch Pharm (Weinheim); 2014 Sep; 347(9):650-7. PubMed ID: 24985336
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Targeting next-generation PDE4 inhibitors in search of potential management of rheumatoid arthritis and psoriasis.
    Bhuktar H; Thirupataiah B; Mounika G; Samarpita S; Rithvik A; Sasi Priya SVS; Naskar R; Medishetti R; Jagadish PC; Parsa KVL; Rasool M; Chakraborty S; Pal M
    Bioorg Chem; 2024 Oct; 151():107689. PubMed ID: 39111119
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Design, synthesis and biological evaluation of novel benzoxaborole derivatives as potent PDE4 inhibitors for topical treatment of atopic dermatitis.
    Chu Z; Xu Q; Zhu Q; Ma X; Mo J; Lin G; Zhao Y; Gu Y; Bian L; Shao L; Guo J; Ye W; Li J; He G; Xu Y
    Eur J Med Chem; 2021 Mar; 213():113171. PubMed ID: 33482600
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Docking Studies of Curcumin and Analogues with Various Phosphodiesterase 4 Subtypes.
    Yi YX; Gaurav A; Akowuah GA
    Curr Drug Discov Technol; 2020; 17(2):248-260. PubMed ID: 30332967
    [TBL] [Abstract][Full Text] [Related]  

  • 19. New insights into PDE4B inhibitor selectivity: CoMFA analyses and molecular docking studies.
    Guariento S; Bruno O; Fossa P; Cichero E
    Mol Divers; 2016 Feb; 20(1):77-92. PubMed ID: 26290462
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis and biological evaluation of 5-carbamoyl-2-phenylpyrimidine derivatives as novel and potent PDE4 inhibitors.
    Goto T; Shiina A; Yoshino T; Mizukami K; Hirahara K; Suzuki O; Sogawa Y; Takahashi T; Mikkaichi T; Nakao N; Takahashi M; Hasegawa M; Sasaki S
    Bioorg Med Chem; 2013 Nov; 21(22):7025-37. PubMed ID: 24094436
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.