BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

371 related articles for article (PubMed ID: 29545311)

  • 1. Derivatization of inhibitor of apoptosis protein (IAP) ligands yields improved inducers of estrogen receptor α degradation.
    Ohoka N; Morita Y; Nagai K; Shimokawa K; Ujikawa O; Fujimori I; Ito M; Hayase Y; Okuhira K; Shibata N; Hattori T; Sameshima T; Sano O; Koyama R; Imaeda Y; Nara H; Cho N; Naito M
    J Biol Chem; 2018 May; 293(18):6776-6790. PubMed ID: 29545311
    [TBL] [Abstract][Full Text] [Related]  

  • 2.
    Ohoka N; Okuhira K; Ito M; Nagai K; Shibata N; Hattori T; Ujikawa O; Shimokawa K; Sano O; Koyama R; Fujita H; Teratani M; Matsumoto H; Imaeda Y; Nara H; Cho N; Naito M
    J Biol Chem; 2017 Mar; 292(11):4556-4570. PubMed ID: 28154167
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Different Degradation Mechanisms of Inhibitor of Apoptosis Proteins (IAPs) by the Specific and Nongenetic IAP-Dependent Protein Eraser (SNIPER).
    Ohoka N; Ujikawa O; Shimokawa K; Sameshima T; Shibata N; Hattori T; Nara H; Cho N; Naito M
    Chem Pharm Bull (Tokyo); 2019 Mar; 67(3):203-209. PubMed ID: 30369550
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Development of protein degradation inducers of oncogenic BCR-ABL protein by conjugation of ABL kinase inhibitors and IAP ligands.
    Shibata N; Miyamoto N; Nagai K; Shimokawa K; Sameshima T; Ohoka N; Hattori T; Imaeda Y; Nara H; Cho N; Naito M
    Cancer Sci; 2017 Aug; 108(8):1657-1666. PubMed ID: 28556300
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Development of hybrid small molecules that induce degradation of estrogen receptor-alpha and necrotic cell death in breast cancer cells.
    Okuhira K; Demizu Y; Hattori T; Ohoka N; Shibata N; Nishimaki-Mogami T; Okuda H; Kurihara M; Naito M
    Cancer Sci; 2013 Nov; 104(11):1492-8. PubMed ID: 23992566
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Protocols for Synthesis of SNIPERs and the Methods to Evaluate the Anticancer Effects.
    Tsukumo Y; Tsuji G; Yokoo H; Shibata N; Ohoka N; Demizu Y; Naito M
    Methods Mol Biol; 2021; 2365():331-347. PubMed ID: 34432253
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Targeted Degradation of Proteins Localized in Subcellular Compartments by Hybrid Small Molecules.
    Okuhira K; Shoda T; Omura R; Ohoka N; Hattori T; Shibata N; Demizu Y; Sugihara R; Ichino A; Kawahara H; Itoh Y; Ishikawa M; Hashimoto Y; Kurihara M; Itoh S; Saito H; Naito M
    Mol Pharmacol; 2017 Mar; 91(3):159-166. PubMed ID: 27965304
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Development of Protein Degradation Inducers of Androgen Receptor by Conjugation of Androgen Receptor Ligands and Inhibitor of Apoptosis Protein Ligands.
    Shibata N; Nagai K; Morita Y; Ujikawa O; Ohoka N; Hattori T; Koyama R; Sano O; Imaeda Y; Nara H; Cho N; Naito M
    J Med Chem; 2018 Jan; 61(2):543-575. PubMed ID: 28594553
    [TBL] [Abstract][Full Text] [Related]  

  • 9. [Development of Protein Knockdown Technology as Emerging Drug Discovery Strategy].
    Ohoka N
    Yakugaku Zasshi; 2018; 138(9):1135-1143. PubMed ID: 30175757
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Molecular Design, Synthesis, and Evaluation of SNIPER(ER) That Induces Proteasomal Degradation of ERα.
    Okuhira K; Demizu Y; Hattori T; Ohoka N; Shibata N; Kurihara M; Naito M
    Methods Mol Biol; 2016; 1366():549-560. PubMed ID: 26585163
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Molecular Design, Synthesis, and Evaluation of SNIPER (ER) that Induces Targeted Protein Degradation of ERα.
    Ohoka N; Yokoo H; Okuhira K; Demizu Y; Naito M
    Methods Mol Biol; 2022; 2418():363-382. PubMed ID: 35119675
    [TBL] [Abstract][Full Text] [Related]  

  • 12. SNIPER(TACC3) induces cytoplasmic vacuolization and sensitizes cancer cells to Bortezomib.
    Ohoka N; Nagai K; Shibata N; Hattori T; Nara H; Cho N; Naito M
    Cancer Sci; 2017 May; 108(5):1032-1041. PubMed ID: 28192613
    [TBL] [Abstract][Full Text] [Related]  

  • 13. SNIPERs-Hijacking IAP activity to induce protein degradation.
    Naito M; Ohoka N; Shibata N
    Drug Discov Today Technol; 2019 Apr; 31():35-42. PubMed ID: 31200857
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Targeted protein degradation and drug discovery.
    Naito M
    J Biochem; 2022 Jul; 172(2):61-69. PubMed ID: 35468190
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Specific non-genetic IAP-based protein erasers (SNIPERs) as a potential therapeutic strategy.
    Ma Z; Ji Y; Yu Y; Liang D
    Eur J Med Chem; 2021 Apr; 216():113247. PubMed ID: 33652355
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Development of BCR-ABL degradation inducers via the conjugation of an imatinib derivative and a cIAP1 ligand.
    Demizu Y; Shibata N; Hattori T; Ohoka N; Motoi H; Misawa T; Shoda T; Naito M; Kurihara M
    Bioorg Med Chem Lett; 2016 Oct; 26(20):4865-4869. PubMed ID: 27666635
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Development of Chimeric Molecules That Degrade the Estrogen Receptor Using Decoy Oligonucleotide Ligands.
    Naganuma M; Ohoka N; Tsuji G; Tsujimura H; Matsuno K; Inoue T; Naito M; Demizu Y
    ACS Med Chem Lett; 2022 Jan; 13(1):134-139. PubMed ID: 35059133
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Design and synthesis of peptide-based chimeric molecules to induce degradation of the estrogen and androgen receptors.
    Yokoo H; Ohoka N; Naito M; Demizu Y
    Bioorg Med Chem; 2020 Aug; 28(15):115595. PubMed ID: 32631565
    [TBL] [Abstract][Full Text] [Related]  

  • 19. ASTX660, a Novel Non-peptidomimetic Antagonist of cIAP1/2 and XIAP, Potently Induces TNFα-Dependent Apoptosis in Cancer Cell Lines and Inhibits Tumor Growth.
    Ward GA; Lewis EJ; Ahn JS; Johnson CN; Lyons JF; Martins V; Munck JM; Rich SJ; Smyth T; Thompson NT; Williams PA; Wilsher NE; Wallis NG; Chessari G
    Mol Cancer Ther; 2018 Jul; 17(7):1381-1391. PubMed ID: 29695633
    [TBL] [Abstract][Full Text] [Related]  

  • 20. CHIP (carboxyl terminus of Hsc70-interacting protein) promotes basal and geldanamycin-induced degradation of estrogen receptor-alpha.
    Fan M; Park A; Nephew KP
    Mol Endocrinol; 2005 Dec; 19(12):2901-14. PubMed ID: 16037132
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 19.