358 related articles for article (PubMed ID: 29551561)
1. Opposing Effects of CREBBP Mutations Govern the Phenotype of Rubinstein-Taybi Syndrome and Adult SHH Medulloblastoma.
Merk DJ; Ohli J; Merk ND; Thatikonda V; Morrissy S; Schoof M; Schmid SN; Harrison L; Filser S; Ahlfeld J; Erkek S; Raithatha K; Andreska T; Weißhaar M; Launspach M; Neumann JE; Shakarami M; Plenker D; Marra MA; Li Y; Mungall AJ; Moore RA; Ma Y; Jones SJM; Lutz B; Ertl-Wagner B; Rossi A; Wagener R; Siebert R; Jung A; Eberhart CG; Lach B; Sendtner M; Pfister SM; Taylor MD; Chavez L; Kool M; Schüller U
Dev Cell; 2018 Mar; 44(6):709-724.e6. PubMed ID: 29551561
[TBL] [Abstract][Full Text] [Related]
2. Rubinstein-Taybi syndrome predisposing to non-WNT, non-SHH, group 3 medulloblastoma.
Bourdeaut F; Miquel C; Richer W; Grill J; Zerah M; Grison C; Pierron G; Amiel J; Krucker C; Radvanyi F; Brugieres L; Delattre O
Pediatr Blood Cancer; 2014 Feb; 61(2):383-6. PubMed ID: 24115570
[TBL] [Abstract][Full Text] [Related]
3. Rubinstein-Taybi syndrome: clinical and molecular overview.
Roelfsema JH; Peters DJ
Expert Rev Mol Med; 2007 Aug; 9(23):1-16. PubMed ID: 17942008
[TBL] [Abstract][Full Text] [Related]
4. Lateral cerebellum is preferentially sensitive to high sonic hedgehog signaling and medulloblastoma formation.
Tan IL; Wojcinski A; Rallapalli H; Lao Z; Sanghrajka RM; Stephen D; Volkova E; Korshunov A; Remke M; Taylor MD; Turnbull DH; Joyner AL
Proc Natl Acad Sci U S A; 2018 Mar; 115(13):3392-3397. PubMed ID: 29531057
[TBL] [Abstract][Full Text] [Related]
5. CREBBP mutations in individuals without Rubinstein-Taybi syndrome phenotype.
Menke LA; van Belzen MJ; Alders M; Cristofoli F; ; Ehmke N; Fergelot P; Foster A; Gerkes EH; Hoffer MJ; Horn D; Kant SG; Lacombe D; Leon E; Maas SM; Melis D; Muto V; Park SM; Peeters H; Peters DJ; Pfundt R; van Ravenswaaij-Arts CM; Tartaglia M; Hennekam RC
Am J Med Genet A; 2016 Oct; 170(10):2681-93. PubMed ID: 27311832
[TBL] [Abstract][Full Text] [Related]
6. Hedgehog pathway permissive conditions allow generation of immortal cell lines from granule cells derived from cancerous and non-cancerous cerebellum.
Heil C
Open Biol; 2019 Jan; 9(1):180145. PubMed ID: 30958113
[TBL] [Abstract][Full Text] [Related]
7. YB-1 is elevated in medulloblastoma and drives proliferation in Sonic hedgehog-dependent cerebellar granule neuron progenitor cells and medulloblastoma cells.
Dey A; Robitaille M; Remke M; Maier C; Malhotra A; Gregorieff A; Wrana JL; Taylor MD; Angers S; Kenney AM
Oncogene; 2016 Aug; 35(32):4256-68. PubMed ID: 26725322
[TBL] [Abstract][Full Text] [Related]
8. Clinical and mutational spectrum in Korean patients with Rubinstein-Taybi syndrome: the spectrum of brain MRI abnormalities.
Lee JS; Byun CK; Kim H; Lim BC; Hwang H; Choi JE; Hwang YS; Seong MW; Park SS; Kim KJ; Chae JH
Brain Dev; 2015 Apr; 37(4):402-8. PubMed ID: 25108505
[TBL] [Abstract][Full Text] [Related]
9. Rubinstein-Taybi Syndrome and Epigenetic Alterations.
Korzus E
Adv Exp Med Biol; 2017; 978():39-62. PubMed ID: 28523540
[TBL] [Abstract][Full Text] [Related]
10. Histone acetylation deficits in lymphoblastoid cell lines from patients with Rubinstein-Taybi syndrome.
Lopez-Atalaya JP; Gervasini C; Mottadelli F; Spena S; Piccione M; Scarano G; Selicorni A; Barco A; Larizza L
J Med Genet; 2012 Jan; 49(1):66-74. PubMed ID: 21984751
[TBL] [Abstract][Full Text] [Related]
11. TCF4 (E2-2) harbors tumor suppressive functions in SHH medulloblastoma.
Hellwig M; Lauffer MC; Bockmayr M; Spohn M; Merk DJ; Harrison L; Ahlfeld J; Kitowski A; Neumann JE; Ohli J; Holdhof D; Niesen J; Schoof M; Kool M; Kraus C; Zweier C; Holmberg D; Schüller U
Acta Neuropathol; 2019 Apr; 137(4):657-673. PubMed ID: 30830316
[TBL] [Abstract][Full Text] [Related]
12. iPSC-derived neurons of CREBBP- and EP300-mutated Rubinstein-Taybi syndrome patients show morphological alterations and hypoexcitability.
Alari V; Russo S; Terragni B; Ajmone PF; Sironi A; Catusi I; Calzari L; Concolino D; Marotta R; Milani D; Giardino D; Mantegazza M; Gervasini C; Finelli P; Larizza L
Stem Cell Res; 2018 Jul; 30():130-140. PubMed ID: 29883886
[TBL] [Abstract][Full Text] [Related]
13. The miR-17/92 polycistron is up-regulated in sonic hedgehog-driven medulloblastomas and induced by N-myc in sonic hedgehog-treated cerebellar neural precursors.
Northcott PA; Fernandez-L A; Hagan JP; Ellison DW; Grajkowska W; Gillespie Y; Grundy R; Van Meter T; Rutka JT; Croce CM; Kenney AM; Taylor MD
Cancer Res; 2009 Apr; 69(8):3249-55. PubMed ID: 19351822
[TBL] [Abstract][Full Text] [Related]
14. Disruption of the ciliary GTPase Arl13b suppresses Sonic hedgehog overactivation and inhibits medulloblastoma formation.
Bay SN; Long AB; Caspary T
Proc Natl Acad Sci U S A; 2018 Feb; 115(7):1570-1575. PubMed ID: 29378965
[TBL] [Abstract][Full Text] [Related]
15. Preferential sensitivity to HDAC inhibitors in tumors with CREBBP mutation.
Hellwig M; Merk DJ; Lutz B; Schüller U
Cancer Gene Ther; 2020 May; 27(5):294-300. PubMed ID: 31068675
[TBL] [Abstract][Full Text] [Related]
16. Transcriptional repressor REST drives lineage stage-specific chromatin compaction at
Dobson THW; Tao RH; Swaminathan J; Maegawa S; Shaik S; Bravo-Alegria J; Sharma A; Kennis B; Yang Y; Callegari K; Haltom AR; Taylor P; Kogiso M; Qi L; Khatua S; Goldman S; Lulla RR; Fangusaro J; MacDonald TJ; Li XN; Hawkins C; Rajaram V; Gopalakrishnan V
Sci Signal; 2019 Jan; 12(565):. PubMed ID: 30670636
[TBL] [Abstract][Full Text] [Related]
17. New insights into genetic variant spectrum and genotype-phenotype correlations of Rubinstein-Taybi syndrome in 39 CREBBP-positive patients.
Pérez-Grijalba V; García-Oguiza A; López M; Armstrong J; García-Miñaur S; Mesa-Latorre JM; O'Callaghan M; Pineda Marfa M; Ramos-Arroyo MA; Santos-Simarro F; Seidel V; Domínguez-Garrido E
Mol Genet Genomic Med; 2019 Nov; 7(11):e972. PubMed ID: 31566936
[TBL] [Abstract][Full Text] [Related]
18. Sox2 requirement in sonic hedgehog-associated medulloblastoma.
Ahlfeld J; Favaro R; Pagella P; Kretzschmar HA; Nicolis S; Schüller U
Cancer Res; 2013 Jun; 73(12):3796-807. PubMed ID: 23596255
[TBL] [Abstract][Full Text] [Related]
19. Hepatocyte growth factor and sonic Hedgehog expression in cerebellar neural progenitor cells costimulate medulloblastoma initiation and growth.
Binning MJ; Niazi T; Pedone CA; Lal B; Eberhart CG; Kim KJ; Laterra J; Fults DW
Cancer Res; 2008 Oct; 68(19):7838-45. PubMed ID: 18829539
[TBL] [Abstract][Full Text] [Related]
20. Neogenin1 is a Sonic Hedgehog target in medulloblastoma and is necessary for cell cycle progression.
Milla LA; Arros A; Espinoza N; Remke M; Kool M; Taylor MD; Pfister SM; Wainwright BJ; Palma V
Int J Cancer; 2014 Jan; 134(1):21-31. PubMed ID: 23775842
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
