These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

149 related articles for article (PubMed ID: 29552126)

  • 1. Mitogen-activated protein kinase inhibitors reduce the nuclear accumulation of phosphorylated Smads by inhibiting Imp 7 or Imp 8 in HepG2 cells.
    Hu X; Kan H; Boye A; Jiang Y; Wu C; Yang Y
    Oncol Lett; 2018 Apr; 15(4):4867-4872. PubMed ID: 29552126
    [TBL] [Abstract][Full Text] [Related]  

  • 2. MAPK inhibitors modulate Smad2/3/4 complex cyto-nuclear translocation in myofibroblasts via Imp7/8 mediation.
    Jiang Y; Wu C; Boye A; Wu J; Wang J; Yang X; Yang Y
    Mol Cell Biochem; 2015 Aug; 406(1-2):255-62. PubMed ID: 25968067
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Compound Astragalus and Salvia miltiorrhiza extracts modulate MAPK-regulated TGF-β/Smad signaling in hepatocellular carcinoma by multi-target mechanism.
    Boye A; Wu C; Jiang Y; Wang J; Wu J; Yang X; Yang Y
    J Ethnopharmacol; 2015 Jul; 169():219-28. PubMed ID: 25934513
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Salvianolic acid B exerts anti-liver fibrosis effects via inhibition of MAPK-mediated phospho-Smad2/3 at linker regions in vivo and in vitro.
    Wu C; Chen W; Ding H; Li D; Wen G; Zhang C; Lu W; Chen M; Yang Y
    Life Sci; 2019 Dec; 239():116881. PubMed ID: 31678285
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Smad2 and Smad3 phosphorylated at both linker and COOH-terminal regions transmit malignant TGF-beta signal in later stages of human colorectal cancer.
    Matsuzaki K; Kitano C; Murata M; Sekimoto G; Yoshida K; Uemura Y; Seki T; Taketani S; Fujisawa J; Okazaki K
    Cancer Res; 2009 Jul; 69(13):5321-30. PubMed ID: 19531654
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Mechanisms of transforming growth factor beta(1)/Smad signalling mediated by mitogen-activated protein kinase pathways in keloid fibroblasts.
    He S; Liu X; Yang Y; Huang W; Xu S; Yang S; Zhang X; Roberts MS
    Br J Dermatol; 2010 Mar; 162(3):538-46. PubMed ID: 19772524
    [TBL] [Abstract][Full Text] [Related]  

  • 7. MAPK inhibitors differently modulate TGF-β/Smad signaling in HepG2 cells.
    Boye A; Kan H; Wu C; Jiang Y; Yang X; He S; Yang Y
    Tumour Biol; 2015 May; 36(5):3643-51. PubMed ID: 25560488
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Preferential utilization of Imp7/8 in nuclear import of Smads.
    Yao X; Chen X; Cottonham C; Xu L
    J Biol Chem; 2008 Aug; 283(33):22867-74. PubMed ID: 18519565
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Inhibition of transforming growth factor (TGF)-beta1-induced extracellular matrix with a novel inhibitor of the TGF-beta type I receptor kinase activity: SB-431542.
    Laping NJ; Grygielko E; Mathur A; Butter S; Bomberger J; Tweed C; Martin W; Fornwald J; Lehr R; Harling J; Gaster L; Callahan JF; Olson BA
    Mol Pharmacol; 2002 Jul; 62(1):58-64. PubMed ID: 12065755
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Smad3 phosphoisoform-mediated signaling during sporadic human colorectal carcinogenesis.
    Matsuzaki K
    Histol Histopathol; 2006 Jun; 21(6):645-62. PubMed ID: 16528675
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Role of mitogen-activated protein kinase in the regulation of transforming growth factor-beta-induced fibronectin accumulation in cultured renal interstitial fibroblasts.
    Suzuki H; Uchida K; Nitta K; Nihei H
    Clin Exp Nephrol; 2004 Sep; 8(3):188-95. PubMed ID: 15480895
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Role of reactive oxygen species in TGF-beta1-induced mitogen-activated protein kinase activation and epithelial-mesenchymal transition in renal tubular epithelial cells.
    Rhyu DY; Yang Y; Ha H; Lee GT; Song JS; Uh ST; Lee HB
    J Am Soc Nephrol; 2005 Mar; 16(3):667-75. PubMed ID: 15677311
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The transforming growth factor-beta/SMAD signaling pathway is present and functional in human mesangial cells.
    Poncelet AC; de Caestecker MP; Schnaper HW
    Kidney Int; 1999 Oct; 56(4):1354-65. PubMed ID: 10504488
    [TBL] [Abstract][Full Text] [Related]  

  • 14. p38 MAPK mediates fibrogenic signal through Smad3 phosphorylation in rat myofibroblasts.
    Furukawa F; Matsuzaki K; Mori S; Tahashi Y; Yoshida K; Sugano Y; Yamagata H; Matsushita M; Seki T; Inagaki Y; Nishizawa M; Fujisawa J; Inoue K
    Hepatology; 2003 Oct; 38(4):879-89. PubMed ID: 14512875
    [TBL] [Abstract][Full Text] [Related]  

  • 15. TGF-beta receptor-mediated signalling through Smad2, Smad3 and Smad4.
    Nakao A; Imamura T; Souchelnytskyi S; Kawabata M; Ishisaki A; Oeda E; Tamaki K; Hanai J; Heldin CH; Miyazono K; ten Dijke P
    EMBO J; 1997 Sep; 16(17):5353-62. PubMed ID: 9311995
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Transforming growth factor-beta1 activates interleukin-6 expression in prostate cancer cells through the synergistic collaboration of the Smad2, p38-NF-kappaB, JNK, and Ras signaling pathways.
    Park JI; Lee MG; Cho K; Park BJ; Chae KS; Byun DS; Ryu BK; Park YK; Chi SG
    Oncogene; 2003 Jul; 22(28):4314-32. PubMed ID: 12853969
    [TBL] [Abstract][Full Text] [Related]  

  • 17. MAPK/AP-1-dependent regulation of PAI-1 gene expression by TGF-beta in rat mesangial cells.
    Guo B; Inoki K; Isono M; Mori H; Kanasaki K; Sugimoto T; Akiba S; Sato T; Yang B; Kikkawa R; Kashiwagi A; Haneda M; Koya D
    Kidney Int; 2005 Sep; 68(3):972-84. PubMed ID: 16105028
    [TBL] [Abstract][Full Text] [Related]  

  • 18. TGF-beta and HGF transmit the signals through JNK-dependent Smad2/3 phosphorylation at the linker regions.
    Mori S; Matsuzaki K; Yoshida K; Furukawa F; Tahashi Y; Yamagata H; Sekimoto G; Seki T; Matsui H; Nishizawa M; Fujisawa J; Okazaki K
    Oncogene; 2004 Sep; 23(44):7416-29. PubMed ID: 15326485
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Transforming growth factor-beta1-dependent activation of Smad2/3 and up-regulation of PAI-1 expression is negatively regulated by Src in SKOV-3 human ovarian cancer cells.
    Wakahara K; Kobayashi H; Yagyu T; Matsuzaki H; Kondo T; Kurita N; Sekino H; Inagaki K; Suzuki M; Kanayama N; Terao T
    J Cell Biochem; 2004 Oct; 93(3):437-53. PubMed ID: 15372629
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Compound Astragalus and Salvia miltiorrhiza extract inhibits hepatocellular carcinoma progression via miR-145/miR-21 mediated Smad3 phosphorylation.
    Wu C; Chen W; Fang M; Boye A; Tao X; Xu Y; Hou S; Yang Y
    J Ethnopharmacol; 2019 Mar; 231():98-112. PubMed ID: 30412748
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.