BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

217 related articles for article (PubMed ID: 29555536)

  • 1. mRNA transfection retrofits cell-based assays with xenobiotic metabolism.
    DeGroot DE; Swank A; Thomas RS; Strynar M; Lee MY; Carmichael PL; Simmons SO
    J Pharmacol Toxicol Methods; 2018; 92():77-94. PubMed ID: 29555536
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Xenobiotic-metabolizing cytochrome P450 enzymes in the human feto-placental unit: role in intrauterine toxicity.
    Hakkola J; Pelkonen O; Pasanen M; Raunio H
    Crit Rev Toxicol; 1998 Jan; 28(1):35-72. PubMed ID: 9493761
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The Alginate Immobilization of Metabolic Enzymes Platform Retrofits an Estrogen Receptor Transactivation Assay With Metabolic Competence.
    Deisenroth C; DeGroot DE; Zurlinden T; Eicher A; McCord J; Lee MY; Carmichael P; Thomas RS
    Toxicol Sci; 2020 Dec; 178(2):281-301. PubMed ID: 32991717
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Up-regulation of CYP expression in hepatoma cells stably transfected by chimeric nuclear receptors.
    Küblbeck J; Reinisalo M; Mustonen R; Honkakoski P
    Eur J Pharm Sci; 2010 Jul; 40(4):263-72. PubMed ID: 20381613
    [TBL] [Abstract][Full Text] [Related]  

  • 5. NADPH-cytochrome P450 reductase expression and enzymatic activity in primary-like human hepatocytes and HepG2 cells for in vitro biotransformation studies.
    Schulz C; Kammerer S; Küpper JH
    Clin Hemorheol Microcirc; 2019; 73(1):249-260. PubMed ID: 31561354
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Comparative aflatoxin B(1) activation and cytotoxicity in human bronchial cells expressing cytochromes P450 1A2 and 3A4.
    Van Vleet TR; Macé K; Coulombe RA
    Cancer Res; 2002 Jan; 62(1):105-12. PubMed ID: 11782366
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Establishment of the transformants expressing human cytochrome P450 subtypes in HepG2, and their applications on drug metabolism and toxicology.
    Yoshitomi S; Ikemoto K; Takahashi J; Miki H; Namba M; Asahi S
    Toxicol In Vitro; 2001 Jun; 15(3):245-56. PubMed ID: 11377097
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Expression of cytochrome P450 (CYP) enzymes in human nonpigmented ciliary epithelial cells: induction of CYP1B1 expression by TCDD.
    Volotinen M; Mäenpää J; Kankuri E; Oksala O; Pelkonen O; Nakajima M; Yokoi T; Hakkola J
    Invest Ophthalmol Vis Sci; 2009 Jul; 50(7):3099-105. PubMed ID: 19324859
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Incorporating population variability and susceptible subpopulations into dosimetry for high-throughput toxicity testing.
    Wetmore BA; Allen B; Clewell HJ; Parker T; Wambaugh JF; Almond LM; Sochaski MA; Thomas RS
    Toxicol Sci; 2014 Nov; 142(1):210-24. PubMed ID: 25145659
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Expression and regulation of xenobiotic-metabolizing cytochrome P450 (CYP) enzymes in human lung.
    Hukkanen J; Pelkonen O; Hakkola J; Raunio H
    Crit Rev Toxicol; 2002 Sep; 32(5):391-411. PubMed ID: 12389869
    [TBL] [Abstract][Full Text] [Related]  

  • 11. An in vitro, high throughput, seven CYP cocktail inhibition assay for the evaluation of new chemical entities using LC-MS/MS.
    Otten JN; Hingorani GP; Hartley DP; Kragerud SD; Franklin RB
    Drug Metab Lett; 2011 Jan; 5(1):17-24. PubMed ID: 21198441
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Network analysis and cross species comparison of protein-protein interaction networks of human, mouse and rat cytochrome P450 proteins that degrade xenobiotics.
    Karthikeyan BS; Akbarsha MA; Parthasarathy S
    Mol Biosyst; 2016 Jun; 12(7):2119-34. PubMed ID: 27194593
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Human cytochrome P450 expression in bacteria: Whole-cell high-throughput activity assay for CYP1A2, 2A6 and 3A4.
    Esteves F; Campelo D; Urban P; Bozonnet S; Lautier T; Rueff J; Truan G; Kranendonk M
    Biochem Pharmacol; 2018 Dec; 158():134-140. PubMed ID: 30308189
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Effect of some indole derivatives on xenobiotic metabolism and xenobiotic-induced toxicity in cultured rat liver slices.
    Renwick AB; Mistry H; Barton PT; Mallet F; Price RJ; Beamand JA; Lake BG
    Food Chem Toxicol; 1999 Jun; 37(6):609-18. PubMed ID: 10478829
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Fluorescence-Based High-Throughput Assays for Investigating Cytochrome P450 Enzyme-Mediated Drug-Drug Interactions.
    He R; Dai Z; Finel M; Zhang F; Tu D; Yang L; Ge G
    Drug Metab Dispos; 2023 Oct; 51(10):1254-1272. PubMed ID: 37349113
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Biochemical basis for the age-related sensitivity of broilers to aflatoxin B1.
    Wang H; Li W; Muhammad I; Sun X; Cui X; Cheng P; Qayum A; Zhang X
    Toxicol Mech Methods; 2018 Jun; 28(5):361-368. PubMed ID: 29327633
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Metabolism and cytotoxicity of aflatoxin b1 in cytochrome p-450-expressing human lung cells.
    Van Vleet TR; Klein PJ; Coulombe RA
    J Toxicol Environ Health A; 2002 Jun; 65(12):853-67. PubMed ID: 12079611
    [TBL] [Abstract][Full Text] [Related]  

  • 18. High-throughput metabolism-induced toxicity assays demonstrated on a 384-pillar plate.
    Yu KN; Kang SY; Hong S; Lee MY
    Arch Toxicol; 2018 Aug; 92(8):2501-2516. PubMed ID: 29974144
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Xenobiotic metabolism in the zebrafish: a review of the spatiotemporal distribution, modulation and activity of Cytochrome P450 families 1 to 3.
    Saad M; Cavanaugh K; Verbueken E; Pype C; Casteleyn C; Van Ginneken C; Van Cruchten S
    J Toxicol Sci; 2016 Feb; 41(1):1-11. PubMed ID: 26763387
    [TBL] [Abstract][Full Text] [Related]  

  • 20. High-Throughput Production of Diverse Xenobiotic Metabolites with Cytochrome P450-Transduced Huh7 Hepatoma Cell Lines.
    Lee CM; Liu KH; Singer G; Miller GW; Li S; Jones DP; Morgan ET
    Drug Metab Dispos; 2022 Sep; 50(9):1182-1189. PubMed ID: 35752443
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.