These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

147 related articles for article (PubMed ID: 29556863)

  • 1. Development of Fc-Fused Cocaine Hydrolase for Cocaine Addiction Treatment: Catalytic and Pharmacokinetic Properties.
    Chen X; Deng J; Cui W; Hou S; Zhang J; Zheng X; Ding X; Wei H; Zhou Z; Kim K; Zhan CG; Zheng F
    AAPS J; 2018 Mar; 20(3):53. PubMed ID: 29556863
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Development of a long-acting Fc-fused cocaine hydrolase with improved yield of protein expression.
    Chen X; Deng J; Zheng X; Zhang J; Zhou Z; Wei H; Zhan CG; Zheng F
    Chem Biol Interact; 2019 Jun; 306():89-95. PubMed ID: 30986387
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Structure-Based Design and Discovery of a Long-Acting Cocaine Hydrolase Mutant with Improved Binding Affinity to Neonatal Fc Receptor for Treatment of Cocaine Abuse.
    Zheng F; Chen X; Kim K; Zhang T; Huang H; Zhou S; Zhang J; Jin Z; Zhan CG
    AAPS J; 2020 Mar; 22(3):62. PubMed ID: 32189158
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Long-acting cocaine hydrolase for addiction therapy.
    Chen X; Xue L; Hou S; Jin Z; Zhang T; Zheng F; Zhan CG
    Proc Natl Acad Sci U S A; 2016 Jan; 113(2):422-7. PubMed ID: 26712009
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Plant expression of cocaine hydrolase-Fc fusion protein for treatment of cocaine abuse.
    Wang G; Zhang T; Huang H; Hou S; Chen X; Zheng F; Zhan CG
    BMC Biotechnol; 2016 Oct; 16(1):72. PubMed ID: 27756365
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Reengineering of Albumin-Fused Cocaine Hydrolase CocH1 (TV-1380) to Prolong Its Biological Half-Life.
    Cai Y; Zhou S; Jin Z; Wei H; Shang L; Deng J; Zhan CG; Zheng F
    AAPS J; 2019 Nov; 22(1):5. PubMed ID: 31754920
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Development of a Highly Efficient Long-Acting Cocaine Hydrolase Entity to Accelerate Cocaine Metabolism.
    Zheng F; Jin Z; Deng J; Chen X; Zheng X; Wang G; Kim K; Shang L; Zhou Z; Zhan CG
    Bioconjug Chem; 2022 Jul; 33(7):1340-1349. PubMed ID: 35767675
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Effects of a cocaine hydrolase engineered from human butyrylcholinesterase on metabolic profile of cocaine in rats.
    Chen X; Zheng X; Zhou Z; Zhan CG; Zheng F
    Chem Biol Interact; 2016 Nov; 259(Pt B):104-109. PubMed ID: 27154495
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Cocaine hydrolase blocks cocaine-induced dopamine transporter trafficking to the plasma membrane.
    Deng J; Kim K; Zheng X; Shang L; Zhan CG; Zheng F
    Addict Biol; 2022 Jan; 27(1):e13089. PubMed ID: 34363291
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Potential anti-obesity effects of a long-acting cocaine hydrolase.
    Zheng X; Deng J; Zhang T; Yao J; Zheng F; Zhan CG
    Chem Biol Interact; 2016 Nov; 259(Pt B):99-103. PubMed ID: 27163854
    [TBL] [Abstract][Full Text] [Related]  

  • 11. PEGylation but Not Fc-Fusion Improves in Vivo Residence Time of a Thermostable Mutant of Bacterial Cocaine Esterase.
    Huang H; Fang L; Xue L; Zhang T; Kim K; Hou S; Zheng F; Zhan CG
    Bioconjug Chem; 2019 Dec; 30(12):3021-3027. PubMed ID: 31661952
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Effectiveness of a Cocaine Hydrolase for Cocaine Toxicity Treatment in Male and Female Rats.
    Zheng X; Zhou Z; Zhang T; Jin Z; Chen X; Deng J; Zhan CG; Zheng F
    AAPS J; 2017 Nov; 20(1):3. PubMed ID: 29181644
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Clinical potential of a rationally engineered enzyme for treatment of cocaine dependence: Long-lasting blocking of the psychostimulant, discriminative stimulus, and reinforcing effects of cocaine.
    Zhang T; Wei H; Deng J; Zheng F; Zhan CG
    Neuropharmacology; 2020 Oct; 176():108251. PubMed ID: 32710979
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Immunoglobulin Fc domain fusion to apolipoprotein(a) kringle V significantly prolongs plasma half-life without affecting its anti-angiogenic activity.
    Yu HK; Lee HJ; Ahn JH; Lim IH; Moon JH; Yoon Y; Yi LS; Kim SJ; Kim JS
    Protein Eng Des Sel; 2013 Jun; 26(6):425-32. PubMed ID: 23571426
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Preparation and in vivo characterization of a cocaine hydrolase engineered from human butyrylcholinesterase for metabolizing cocaine.
    Xue L; Hou S; Tong M; Fang L; Chen X; Jin Z; Tai HH; Zheng F; Zhan CG
    Biochem J; 2013 Aug; 453(3):447-54. PubMed ID: 23849058
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A thermally stable form of bacterial cocaine esterase: a potential therapeutic agent for treatment of cocaine abuse.
    Brim RL; Nance MR; Youngstrom DW; Narasimhan D; Zhan CG; Tesmer JJ; Sunahara RK; Woods JH
    Mol Pharmacol; 2010 Apr; 77(4):593-600. PubMed ID: 20086035
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Catalytic activities of cocaine hydrolases against the most toxic cocaine metabolite norcocaethylene.
    Zheng X; Chen X; Zhang T; Zhan M; Zhan CG; Zheng F
    Org Biomol Chem; 2020 Mar; 18(10):1968-1977. PubMed ID: 32101217
    [TBL] [Abstract][Full Text] [Related]  

  • 18. [Expression of rhEPO-L-Fc fusion protein and analysis of its bioactivity and pharmacokinetics].
    Zhu Q; Huang Z; Huang Y; Qin Y
    Sheng Wu Gong Cheng Xue Bao; 2008 Nov; 24(11):1874-9. PubMed ID: 19256332
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Catalytic activities of a highly efficient cocaine hydrolase for hydrolysis of biologically active cocaine metabolites norcocaine and benzoylecgonine.
    Shang L; Jin Z; Wei H; Park S; Zhan CG; Zheng F
    Sci Rep; 2023 Jan; 13(1):640. PubMed ID: 36635293
    [TBL] [Abstract][Full Text] [Related]  

  • 20. An albumin-butyrylcholinesterase for cocaine toxicity and addiction: catalytic and pharmacokinetic properties.
    Gao Y; LaFleur D; Shah R; Zhao Q; Singh M; Brimijoin S
    Chem Biol Interact; 2008 Sep; 175(1-3):83-7. PubMed ID: 18514640
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.