724 related articles for article (PubMed ID: 29562314)
1. TDP-43 regulates the alternative splicing of hnRNP A1 to yield an aggregation-prone variant in amyotrophic lateral sclerosis.
Deshaies JE; Shkreta L; Moszczynski AJ; Sidibé H; Semmler S; Fouillen A; Bennett ER; Bekenstein U; Destroismaisons L; Toutant J; Delmotte Q; Volkening K; Stabile S; Aulas A; Khalfallah Y; Soreq H; Nanci A; Strong MJ; Chabot B; Vande Velde C
Brain; 2018 May; 141(5):1320-1333. PubMed ID: 29562314
[TBL] [Abstract][Full Text] [Related]
2. Loss of hnRNPA1 in ALS spinal cord motor neurons with TDP-43-positive inclusions.
Honda H; Hamasaki H; Wakamiya T; Koyama S; Suzuki SO; Fujii N; Iwaki T
Neuropathology; 2015 Feb; 35(1):37-43. PubMed ID: 25338872
[TBL] [Abstract][Full Text] [Related]
3. Increased cytoplasmic TARDBP mRNA in affected spinal motor neurons in ALS caused by abnormal autoregulation of TDP-43.
Koyama A; Sugai A; Kato T; Ishihara T; Shiga A; Toyoshima Y; Koyama M; Konno T; Hirokawa S; Yokoseki A; Nishizawa M; Kakita A; Takahashi H; Onodera O
Nucleic Acids Res; 2016 Jul; 44(12):5820-36. PubMed ID: 27257061
[TBL] [Abstract][Full Text] [Related]
4. Quantification of the Relative Contributions of Loss-of-function and Gain-of-function Mechanisms in TAR DNA-binding Protein 43 (TDP-43) Proteinopathies.
Cascella R; Capitini C; Fani G; Dobson CM; Cecchi C; Chiti F
J Biol Chem; 2016 Sep; 291(37):19437-48. PubMed ID: 27445339
[TBL] [Abstract][Full Text] [Related]
5. TDP-43 mutations causing amyotrophic lateral sclerosis are associated with altered expression of RNA-binding protein hnRNP K and affect the Nrf2 antioxidant pathway.
Moujalled D; Grubman A; Acevedo K; Yang S; Ke YD; Moujalled DM; Duncan C; Caragounis A; Perera ND; Turner BJ; Prudencio M; Petrucelli L; Blair I; Ittner LM; Crouch PJ; Liddell JR; White AR
Hum Mol Genet; 2017 May; 26(9):1732-1746. PubMed ID: 28334913
[TBL] [Abstract][Full Text] [Related]
6. Transactive response DNA-binding protein 43 (TDP-43) regulates alternative splicing of tau exon 10: Implications for the pathogenesis of tauopathies.
Gu J; Chen F; Iqbal K; Gong CX; Wang X; Liu F
J Biol Chem; 2017 Jun; 292(25):10600-10612. PubMed ID: 28487370
[TBL] [Abstract][Full Text] [Related]
7. Low molecular weight species of TDP-43 generated by abnormal splicing form inclusions in amyotrophic lateral sclerosis and result in motor neuron death.
Xiao S; Sanelli T; Chiang H; Sun Y; Chakrabartty A; Keith J; Rogaeva E; Zinman L; Robertson J
Acta Neuropathol; 2015 Jul; 130(1):49-61. PubMed ID: 25788357
[TBL] [Abstract][Full Text] [Related]
8. PARylation regulates stress granule dynamics, phase separation, and neurotoxicity of disease-related RNA-binding proteins.
Duan Y; Du A; Gu J; Duan G; Wang C; Gui X; Ma Z; Qian B; Deng X; Zhang K; Sun L; Tian K; Zhang Y; Jiang H; Liu C; Fang Y
Cell Res; 2019 Mar; 29(3):233-247. PubMed ID: 30728452
[TBL] [Abstract][Full Text] [Related]
9. TDP-43 functions within a network of hnRNP proteins to inhibit the production of a truncated human SORT1 receptor.
Mohagheghi F; Prudencio M; Stuani C; Cook C; Jansen-West K; Dickson DW; Petrucelli L; Buratti E
Hum Mol Genet; 2016 Feb; 25(3):534-45. PubMed ID: 26614389
[TBL] [Abstract][Full Text] [Related]
10. Tethering-induced destabilization and ATP-binding for tandem RRM domains of ALS-causing TDP-43 and hnRNPA1.
Dang M; Li Y; Song J
Sci Rep; 2021 Jan; 11(1):1034. PubMed ID: 33441818
[TBL] [Abstract][Full Text] [Related]
11. Divergent roles of ALS-linked proteins FUS/TLS and TDP-43 intersect in processing long pre-mRNAs.
Lagier-Tourenne C; Polymenidou M; Hutt KR; Vu AQ; Baughn M; Huelga SC; Clutario KM; Ling SC; Liang TY; Mazur C; Wancewicz E; Kim AS; Watt A; Freier S; Hicks GG; Donohue JP; Shiue L; Bennett CF; Ravits J; Cleveland DW; Yeo GW
Nat Neurosci; 2012 Nov; 15(11):1488-97. PubMed ID: 23023293
[TBL] [Abstract][Full Text] [Related]
12. Non-genetically modified models exhibit TARDBP mRNA increase due to perturbed TDP-43 autoregulation.
Sugai A; Kato T; Koyama A; Koike Y; Konno T; Ishihara T; Onodera O
Neurobiol Dis; 2019 Oct; 130():104534. PubMed ID: 31310801
[TBL] [Abstract][Full Text] [Related]
13. hnRNP A1 Regulates Alternative Splicing of Tau Exon 10 by Targeting 3' Splice Sites.
Liu Y; Kim D; Choi N; Oh J; Ha J; Zhou J; Zheng X; Shen H
Cells; 2020 Apr; 9(4):. PubMed ID: 32290247
[TBL] [Abstract][Full Text] [Related]
14. Pathological TDP-43 changes in Betz cells differ from those in bulbar and spinal α-motoneurons in sporadic amyotrophic lateral sclerosis.
Braak H; Ludolph AC; Neumann M; Ravits J; Del Tredici K
Acta Neuropathol; 2017 Jan; 133(1):79-90. PubMed ID: 27757524
[TBL] [Abstract][Full Text] [Related]
15. Distinct responses of neurons and astrocytes to TDP-43 proteinopathy in amyotrophic lateral sclerosis.
Smethurst P; Risse E; Tyzack GE; Mitchell JS; Taha DM; Chen YR; Newcombe J; Collinge J; Sidle K; Patani R
Brain; 2020 Feb; 143(2):430-440. PubMed ID: 32040555
[TBL] [Abstract][Full Text] [Related]
16. Loss of nuclear TDP-43 in amyotrophic lateral sclerosis (ALS) causes altered expression of splicing machinery and widespread dysregulation of RNA splicing in motor neurones.
Highley JR; Kirby J; Jansweijer JA; Webb PS; Hewamadduma CA; Heath PR; Higginbottom A; Raman R; Ferraiuolo L; Cooper-Knock J; McDermott CJ; Wharton SB; Shaw PJ; Ince PG
Neuropathol Appl Neurobiol; 2014 Oct; 40(6):670-85. PubMed ID: 24750229
[TBL] [Abstract][Full Text] [Related]
17. Mice with endogenous TDP-43 mutations exhibit gain of splicing function and characteristics of amyotrophic lateral sclerosis.
Fratta P; Sivakumar P; Humphrey J; Lo K; Ricketts T; Oliveira H; Brito-Armas JM; Kalmar B; Ule A; Yu Y; Birsa N; Bodo C; Collins T; Conicella AE; Mejia Maza A; Marrero-Gagliardi A; Stewart M; Mianne J; Corrochano S; Emmett W; Codner G; Groves M; Fukumura R; Gondo Y; Lythgoe M; Pauws E; Peskett E; Stanier P; Teboul L; Hallegger M; Calvo A; Chiò A; Isaacs AM; Fawzi NL; Wang E; Housman DE; Baralle F; Greensmith L; Buratti E; Plagnol V; Fisher EM; Acevedo-Arozena A
EMBO J; 2018 Jun; 37(11):. PubMed ID: 29764981
[TBL] [Abstract][Full Text] [Related]
18. MTHFSD and DDX58 are novel RNA-binding proteins abnormally regulated in amyotrophic lateral sclerosis.
MacNair L; Xiao S; Miletic D; Ghani M; Julien JP; Keith J; Zinman L; Rogaeva E; Robertson J
Brain; 2016 Jan; 139(Pt 1):86-100. PubMed ID: 26525917
[TBL] [Abstract][Full Text] [Related]
19. Point mutations in the N-terminal domain of transactive response DNA-binding protein 43 kDa (TDP-43) compromise its stability, dimerization, and functions.
Mompeán M; Romano V; Pantoja-Uceda D; Stuani C; Baralle FE; Buratti E; Laurents DV
J Biol Chem; 2017 Jul; 292(28):11992-12006. PubMed ID: 28566288
[TBL] [Abstract][Full Text] [Related]
20. Quantitative analysis of cryptic splicing associated with TDP-43 depletion.
Humphrey J; Emmett W; Fratta P; Isaacs AM; Plagnol V
BMC Med Genomics; 2017 May; 10(1):38. PubMed ID: 28549443
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
