336 related articles for article (PubMed ID: 29571157)
1. Antimalarial agents against both sexual and asexual parasites stages: structure-activity relationships and biological studies of the Malaria Box compound 1-[5-(4-bromo-2-chlorophenyl)furan-2-yl]-N-[(piperidin-4-yl)methyl]methanamine (MMV019918) and analogues.
Vallone A; D'Alessandro S; Brogi S; Brindisi M; Chemi G; Alfano G; Lamponi S; Lee SG; Jez JM; Koolen KJM; Dechering KJ; Saponara S; Fusi F; Gorelli B; Taramelli D; Parapini S; Caldelari R; Campiani G; Gemma S; Butini S
Eur J Med Chem; 2018 Apr; 150():698-718. PubMed ID: 29571157
[TBL] [Abstract][Full Text] [Related]
2. Computational and experimental elucidation of Plasmodium falciparum phosphoethanolamine methyltransferase inhibitors: Pivotal drug target.
Singh J; Vijay S; Mansuri R; Rawal R; Kadian K; Sahoo GC; Kumar M; Sharma A
PLoS One; 2019; 14(8):e0221032. PubMed ID: 31437171
[TBL] [Abstract][Full Text] [Related]
3. The cytoplasmic prolyl-tRNA synthetase of the malaria parasite is a dual-stage target of febrifugine and its analogs.
Herman JD; Pepper LR; Cortese JF; Estiu G; Galinsky K; Zuzarte-Luis V; Derbyshire ER; Ribacke U; Lukens AK; Santos SA; Patel V; Clish CB; Sullivan WJ; Zhou H; Bopp SE; Schimmel P; Lindquist S; Clardy J; Mota MM; Keller TL; Whitman M; Wiest O; Wirth DF; Mazitschek R
Sci Transl Med; 2015 May; 7(288):288ra77. PubMed ID: 25995223
[TBL] [Abstract][Full Text] [Related]
4. Interrogating alkyl and arylalkylpolyamino (bis)urea and (bis)thiourea isosteres as potent antimalarial chemotypes against multiple lifecycle forms of Plasmodium falciparum parasites.
Verlinden BK; de Beer M; Pachaiyappan B; Besaans E; Andayi WA; Reader J; Niemand J; van Biljon R; Guy K; Egan T; Woster PM; Birkholtz LM
Bioorg Med Chem; 2015 Aug; 23(16):5131-43. PubMed ID: 25684422
[TBL] [Abstract][Full Text] [Related]
5. Identification of MMV malaria box inhibitors of plasmodium falciparum early-stage gametocytes using a luciferase-based high-throughput assay.
Lucantoni L; Duffy S; Adjalley SH; Fidock DA; Avery VM
Antimicrob Agents Chemother; 2013 Dec; 57(12):6050-62. PubMed ID: 24060871
[TBL] [Abstract][Full Text] [Related]
6. Design, synthesis and biological evaluation of small molecules as potent glucosidase inhibitors.
Hati S; Madurkar SM; Bathula C; Thulluri C; Agarwal R; Siddiqui FA; Dangi P; Adepally U; Singh A; Singh S; Sen S
Eur J Med Chem; 2015 Jul; 100():188-96. PubMed ID: 26087029
[TBL] [Abstract][Full Text] [Related]
7. In vitro Multistage Malaria Transmission Blocking Activity of Selected Malaria Box Compounds.
Malebo HM; D'Alessandro S; Ebstie YA; Sorè H; Tenoh Guedoung AR; Katani SJ; Parapini S; Taramelli D; Habluetzel A
Drug Des Devel Ther; 2020; 14():1593-1607. PubMed ID: 32425505
[TBL] [Abstract][Full Text] [Related]
8. Synthesis, characterization and in vitro evaluation of novel enantiomerically-pure sulphonamide antimalarials.
Anusha S; Sinha A; Babu Rajeev CP; Chu TT; Mathai J; Ximei H; Fuchs JE; Shivananju N; Bender A; Preiser PR; Rangappa KS; Basappa ; Chandramohanadas R
Org Biomol Chem; 2015 Nov; 13(43):10681-90. PubMed ID: 26347024
[TBL] [Abstract][Full Text] [Related]
9. Structure activity refinement of phenylsulfonyl piperazines as antimalarials that block erythrocytic invasion.
Nguyen W; Dans MG; Ngo A; Gancheva MR; Romeo O; Duffy S; de Koning-Ward TF; Lowes KN; Sabroux HJ; Avery VM; Wilson DW; Gilson PR; Sleebs BE
Eur J Med Chem; 2021 Mar; 214():113253. PubMed ID: 33610028
[TBL] [Abstract][Full Text] [Related]
10. Ivermectin Impairs the Development of Sexual and Asexual Stages of Plasmodium falciparum
de Carvalho LP; Sandri TL; José Tenório de Melo E; Fendel R; Kremsner PG; Mordmüller B; Held J
Antimicrob Agents Chemother; 2019 Aug; 63(8):. PubMed ID: 31109978
[TBL] [Abstract][Full Text] [Related]
11. A New Set of Chemical Starting Points with Plasmodium falciparum Transmission-Blocking Potential for Antimalarial Drug Discovery.
Almela MJ; Lozano S; Lelièvre J; Colmenarejo G; Coterón JM; Rodrigues J; Gonzalez C; Herreros E
PLoS One; 2015; 10(8):e0135139. PubMed ID: 26317851
[TBL] [Abstract][Full Text] [Related]
12. Discovery of HDAC inhibitors with potent activity against multiple malaria parasite life cycle stages.
Hansen FK; Sumanadasa SD; Stenzel K; Duffy S; Meister S; Marek L; Schmetter R; Kuna K; Hamacher A; Mordmüller B; Kassack MU; Winzeler EA; Avery VM; Andrews KT; Kurz T
Eur J Med Chem; 2014 Jul; 82():204-13. PubMed ID: 24904967
[TBL] [Abstract][Full Text] [Related]
13. Antimalarial and antiplasmodial activities of norneolignans. Syntheses and SAR.
Skytte DM; Nielsen SF; Chen M; Zhai L; Olsen CE; Christensen SB
J Med Chem; 2006 Jan; 49(1):436-40. PubMed ID: 16392829
[TBL] [Abstract][Full Text] [Related]
14. Plasmodium falciparum dihydroorotate dehydrogenase: a drug target against malaria.
Hoelz LV; Calil FA; Nonato MC; Pinheiro LC; Boechat N
Future Med Chem; 2018 Aug; 10(15):1853-1874. PubMed ID: 30019917
[TBL] [Abstract][Full Text] [Related]
15. De novo lead optimization of triazine derivatives identifies potent antimalarials.
Shandilya A; Hoda N; Khan S; Jameel E; Kumar J; Jayaram B
J Mol Graph Model; 2017 Jan; 71():96-103. PubMed ID: 27880887
[TBL] [Abstract][Full Text] [Related]
16. Targeting Asexual and Sexual Blood Stages of the Human Malaria Parasite P. falciparum with 7-Chloroquinoline-Based 1,2,3-Triazoles.
Wadi I; Prasad D; Batra N; Srivastava K; Anvikar AR; Valecha N; Nath M
ChemMedChem; 2019 Feb; 14(4):484-493. PubMed ID: 30609264
[TBL] [Abstract][Full Text] [Related]
17. Design and Synthesis of Terephthalic Acid-Based Histone Deacetylase Inhibitors with Dual-Stage Anti-Plasmodium Activity.
Stenzel K; Chua MJ; Duffy S; Antonova-Koch Y; Meister S; Hamacher A; Kassack MU; Winzeler E; Avery VM; Kurz T; Andrews KT; Hansen FK
ChemMedChem; 2017 Oct; 12(19):1627-1636. PubMed ID: 28812327
[TBL] [Abstract][Full Text] [Related]
18. Ferrocene-pyrimidine conjugates: Synthesis, electrochemistry, physicochemical properties and antiplasmodial activities.
Chopra R; de Kock C; Smith P; Chibale K; Singh K
Eur J Med Chem; 2015 Jul; 100():1-9. PubMed ID: 26057222
[TBL] [Abstract][Full Text] [Related]
19. In vitro dual activity of Aloe marlothii roots and its chemical constituents against Plasmodium falciparum asexual and sexual stage parasites.
Mianda SM; Invernizzi L; van der Watt ME; Reader J; Moyo P; Birkholtz LM; Maharaj VJ
J Ethnopharmacol; 2022 Oct; 297():115551. PubMed ID: 35850311
[TBL] [Abstract][Full Text] [Related]
20. Evaluation of analogues of furan-amidines as inhibitors of NQO2.
Alnabulsi S; Hussein B; Santina E; Alsalahat I; Kadirvel M; Magwaza RN; Bryce RA; Schwalbe CH; Baldwin AG; Russo I; Stratford IJ; Freeman S
Bioorg Med Chem Lett; 2018 May; 28(8):1292-1297. PubMed ID: 29567345
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
