189 related articles for article (PubMed ID: 29572350)
1. Gain-of-function mutations in granulocyte colony-stimulating factor receptor (CSF3R) reveal distinct mechanisms of CSF3R activation.
Zhang H; Coblentz C; Watanabe-Smith K; Means S; Means J; Maxson JE; Tyner JW
J Biol Chem; 2018 May; 293(19):7387-7396. PubMed ID: 29572350
[TBL] [Abstract][Full Text] [Related]
2. Ligand independence of the T618I mutation in the colony-stimulating factor 3 receptor (CSF3R) protein results from loss of O-linked glycosylation and increased receptor dimerization.
Maxson JE; Luty SB; MacManiman JD; Abel ML; Druker BJ; Tyner JW
J Biol Chem; 2014 Feb; 289(9):5820-7. PubMed ID: 24403076
[TBL] [Abstract][Full Text] [Related]
3. The Colony-Stimulating Factor 3 Receptor T640N Mutation Is Oncogenic, Sensitive to JAK Inhibition, and Mimics T618I.
Maxson JE; Luty SB; MacManiman JD; Paik JC; Gotlib J; Greenberg P; Bahamadi S; Savage SL; Abel ML; Eide CA; Loriaux MM; Stevens EA; Tyner JW
Clin Cancer Res; 2016 Feb; 22(3):757-64. PubMed ID: 26475333
[TBL] [Abstract][Full Text] [Related]
4. Characterization of the leukemogenic potential of distal cytoplasmic CSF3R truncation and missense mutations.
Zhang H; Reister Schultz A; Luty S; Rofelty A; Su Y; Means S; Bottomly D; Wilmot B; McWeeney SK; Tyner JW
Leukemia; 2017 Dec; 31(12):2752-2760. PubMed ID: 28439110
[TBL] [Abstract][Full Text] [Related]
5. Effect of the unfolded protein response and oxidative stress on mutagenesis in CSF3R: a model for evolution of severe congenital neutropenia to myelodysplastic syndrome/acute myeloid leukemia.
Sapra A; Jaksik R; Mehta H; Biesiadny S; Kimmel M; Corey SJ
Mutagenesis; 2020 Dec; 35(5):381-389. PubMed ID: 33511998
[TBL] [Abstract][Full Text] [Related]
6. T618I CSF3R mutations in chronic neutrophilic leukemia induce oncogenic signals through aberrant trafficking and constitutive phosphorylation of the O-glycosylated receptor form.
Price A; Druhan LJ; Lance A; Clark G; Vestal CG; Zhang Q; Foureau D; Parsons J; Hamilton A; Steuerwald NM; Avalos BR
Biochem Biophys Res Commun; 2020 Feb; 523(1):208-213. PubMed ID: 31848046
[TBL] [Abstract][Full Text] [Related]
7. Mutational screens highlight glycosylation as a modulator of colony-stimulating factor 3 receptor (CSF3R) activity.
Hollander MJ; Malaker SA; Riley NM; Perez I; Abney NM; Gray MA; Maxson JE; Cochran JR; Bertozzi CR
J Biol Chem; 2023 Jun; 299(6):104755. PubMed ID: 37116708
[TBL] [Abstract][Full Text] [Related]
8. Janus kinases promote cell-surface expression and provoke autonomous signalling from routing-defective G-CSF receptors.
Meenhuis A; Irandoust M; Wölfler A; Roovers O; Valkhof M; Touw IP
Biochem J; 2009 Feb; 417(3):737-46. PubMed ID: 18922133
[TBL] [Abstract][Full Text] [Related]
9. A Novel Germline Variant in CSF3R Reduces N-Glycosylation and Exerts Potent Oncogenic Effects in Leukemia.
Spiciarich DR; Oh ST; Foley A; Hughes SB; Mauro MJ; Abdel-Wahab O; Press RD; Viner R; Thompson SL; Chen Q; Azadi P; Bertozzi CR; Maxson JE
Cancer Res; 2018 Dec; 78(24):6762-6770. PubMed ID: 30348809
[TBL] [Abstract][Full Text] [Related]
10. Unpaired Extracellular Cysteine Mutations of CSF3R Mediate Gain or Loss of Function.
Zhang H; Means S; Schultz AR; Watanabe-Smith K; Medeiros BC; Bottomly D; Wilmot B; McWeeney SK; Kükenshöner T; Hantschel O; Tyner JW
Cancer Res; 2017 Aug; 77(16):4258-4267. PubMed ID: 28652245
[TBL] [Abstract][Full Text] [Related]
11. Colony Stimulating Factor 3 Mutations and Myeloid Malignancies.
Xing Y; Zhao MF
Zhongguo Yi Xue Ke Xue Yuan Xue Bao; 2016 Feb; 38(1):103-7. PubMed ID: 26956865
[TBL] [Abstract][Full Text] [Related]
12. A Truncated Granulocyte Colony-stimulating Factor Receptor (G-CSFR) Inhibits Apoptosis Induced by Neutrophil Elastase G185R Mutant: IMPLICATION FOR UNDERSTANDING CSF3R GENE MUTATIONS IN SEVERE CONGENITAL NEUTROPENIA.
Qiu Y; Zhang Y; Hu N; Dong F
J Biol Chem; 2017 Feb; 292(8):3496-3505. PubMed ID: 28073911
[TBL] [Abstract][Full Text] [Related]
13. In vivo expansion of cells expressing acquired CSF3R mutations in patients with severe congenital neutropenia.
Germeshausen M; Welte K; Ballmaier M
Blood; 2009 Jan; 113(3):668-70. PubMed ID: 19020310
[TBL] [Abstract][Full Text] [Related]
14. Role of CSF3R mutations in the pathomechanism of congenital neutropenia and secondary acute myeloid leukemia.
Klimiankou M; Mellor-Heineke S; Zeidler C; Welte K; Skokowa J
Ann N Y Acad Sci; 2016 Apr; 1370(1):119-25. PubMed ID: 27270496
[TBL] [Abstract][Full Text] [Related]
15. Heterozygous germ line CSF3R variants as risk alleles for development of hematologic malignancies.
Trottier AM; Druhan LJ; Kraft IL; Lance A; Feurstein S; Helgeson M; Segal JP; Das S; Avalos BR; Godley LA
Blood Adv; 2020 Oct; 4(20):5269-5284. PubMed ID: 33108454
[TBL] [Abstract][Full Text] [Related]
16. Incidence of CSF3R mutations in severe congenital neutropenia and relevance for leukemogenesis: Results of a long-term survey.
Germeshausen M; Ballmaier M; Welte K
Blood; 2007 Jan; 109(1):93-9. PubMed ID: 16985178
[TBL] [Abstract][Full Text] [Related]
17. Constitutively activating mutations of c-kit receptor tyrosine kinase confer factor-independent growth and tumorigenicity of factor-dependent hematopoietic cell lines.
Kitayama H; Kanakura Y; Furitsu T; Tsujimura T; Oritani K; Ikeda H; Sugahara H; Mitsui H; Kanayama Y; Kitamura Y
Blood; 1995 Feb; 85(3):790-8. PubMed ID: 7530509
[TBL] [Abstract][Full Text] [Related]
18. Cooperativity of RUNX1 and CSF3R mutations in severe congenital neutropenia: a unique pathway in myeloid leukemogenesis.
Skokowa J; Steinemann D; Katsman-Kuipers JE; Zeidler C; Klimenkova O; Klimiankou M; Unalan M; Kandabarau S; Makaryan V; Beekman R; Behrens K; Stocking C; Obenauer J; Schnittger S; Kohlmann A; Valkhof MG; Hoogenboezem R; Göhring G; Reinhardt D; Schlegelberger B; Stanulla M; Vandenberghe P; Donadieu J; Zwaan CM; Touw IP; van den Heuvel-Eibrink MM; Dale DC; Welte K
Blood; 2014 Apr; 123(14):2229-37. PubMed ID: 24523240
[TBL] [Abstract][Full Text] [Related]
19. An activating mutation in the CSF3R gene induces a hereditary chronic neutrophilia.
Plo I; Zhang Y; Le Couédic JP; Nakatake M; Boulet JM; Itaya M; Smith SO; Debili N; Constantinescu SN; Vainchenker W; Louache F; de Botton S
J Exp Med; 2009 Aug; 206(8):1701-7. PubMed ID: 19620628
[TBL] [Abstract][Full Text] [Related]
20. A congenital CSF3R mutation in chronic neutropenia reveals a vital role for a cytokine receptor extracellular hinge motif in the response to granulocyte colony-stimulating factor.
Feyen J; Ernst MPT; van der Velden VHJ; Valk PJM; Broeders L; Touw IP; Raaijmakers MHGP
Pediatr Blood Cancer; 2023 Apr; 70(4):e30039. PubMed ID: 36316822
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
