485 related articles for article (PubMed ID: 29572438)
1. Interruption of lactate uptake by inhibiting mitochondrial pyruvate transport unravels direct antitumor and radiosensitizing effects.
Corbet C; Bastien E; Draoui N; Doix B; Mignion L; Jordan BF; Marchand A; Vanherck JC; Chaltin P; Schakman O; Becker HM; Riant O; Feron O
Nat Commun; 2018 Mar; 9(1):1208. PubMed ID: 29572438
[TBL] [Abstract][Full Text] [Related]
2. The anti-tumour agent lonidamine is a potent inhibitor of the mitochondrial pyruvate carrier and plasma membrane monocarboxylate transporters.
Nancolas B; Guo L; Zhou R; Nath K; Nelson DS; Leeper DB; Blair IA; Glickson JD; Halestrap AP
Biochem J; 2016 Apr; 473(7):929-36. PubMed ID: 26831515
[TBL] [Abstract][Full Text] [Related]
3. MCT1 Modulates Cancer Cell Pyruvate Export and Growth of Tumors that Co-express MCT1 and MCT4.
Hong CS; Graham NA; Gu W; Espindola Camacho C; Mah V; Maresh EL; Alavi M; Bagryanova L; Krotee PAL; Gardner BK; Behbahan IS; Horvath S; Chia D; Mellinghoff IK; Hurvitz SA; Dubinett SM; Critchlow SE; Kurdistani SK; Goodglick L; Braas D; Graeber TG; Christofk HR
Cell Rep; 2016 Feb; 14(7):1590-1601. PubMed ID: 26876179
[TBL] [Abstract][Full Text] [Related]
4. Mechanism of antineoplastic activity of lonidamine.
Nath K; Guo L; Nancolas B; Nelson DS; Shestov AA; Lee SC; Roman J; Zhou R; Leeper DB; Halestrap AP; Blair IA; Glickson JD
Biochim Biophys Acta; 2016 Dec; 1866(2):151-162. PubMed ID: 27497601
[TBL] [Abstract][Full Text] [Related]
5. Hyperpolarized [1-
Rao Y; Gammon S; Zacharias NM; Liu T; Salzillo T; Xi Y; Wang J; Bhattacharya P; Piwnica-Worms D
Proc Natl Acad Sci U S A; 2020 Sep; 117(36):22378-22389. PubMed ID: 32839325
[TBL] [Abstract][Full Text] [Related]
6. Identification of key binding site residues of MCT1 for AR-C155858 reveals the molecular basis of its isoform selectivity.
Nancolas B; Sessions RB; Halestrap AP
Biochem J; 2015 Feb; 466(1):177-88. PubMed ID: 25437897
[TBL] [Abstract][Full Text] [Related]
7. MCT4 as a potential therapeutic target for metastatic gastric cancer with peritoneal carcinomatosis.
Lee JY; Lee I; Chang WJ; Ahn SM; Lim SH; Kim HS; Yoo KH; Jung KS; Song HN; Cho JH; Kim SY; Kim KM; Lee S; Kim ST; Park SH; Lee J; Park JO; Park YS; Lim HY; Kang WK
Oncotarget; 2016 Jul; 7(28):43492-43503. PubMed ID: 27224918
[TBL] [Abstract][Full Text] [Related]
8. The pyruvate-lactate axis modulates cardiac hypertrophy and heart failure.
Cluntun AA; Badolia R; Lettlova S; Parnell KM; Shankar TS; Diakos NA; Olson KA; Taleb I; Tatum SM; Berg JA; Cunningham CN; Van Ry T; Bott AJ; Krokidi AT; Fogarty S; Skedros S; Swiatek WI; Yu X; Luo B; Merx S; Navankasattusas S; Cox JE; Ducker GS; Holland WL; McKellar SH; Rutter J; Drakos SG
Cell Metab; 2021 Mar; 33(3):629-648.e10. PubMed ID: 33333007
[TBL] [Abstract][Full Text] [Related]
9. miR-29a and miR-29b contribute to pancreatic beta-cell-specific silencing of monocarboxylate transporter 1 (Mct1).
Pullen TJ; da Silva Xavier G; Kelsey G; Rutter GA
Mol Cell Biol; 2011 Aug; 31(15):3182-94. PubMed ID: 21646425
[TBL] [Abstract][Full Text] [Related]
10. Targeting lactate-fueled respiration selectively kills hypoxic tumor cells in mice.
Sonveaux P; Végran F; Schroeder T; Wergin MC; Verrax J; Rabbani ZN; De Saedeleer CJ; Kennedy KM; Diepart C; Jordan BF; Kelley MJ; Gallez B; Wahl ML; Feron O; Dewhirst MW
J Clin Invest; 2008 Dec; 118(12):3930-42. PubMed ID: 19033663
[TBL] [Abstract][Full Text] [Related]
11. Preclinical Efficacy of the Novel Monocarboxylate Transporter 1 Inhibitor BAY-8002 and Associated Markers of Resistance.
Quanz M; Bender E; Kopitz C; Grünewald S; Schlicker A; Schwede W; Eheim A; Toschi L; Neuhaus R; Richter C; Toedling J; Merz C; Lesche R; Kamburov A; Siebeneicher H; Bauser M; Hägebarth A
Mol Cancer Ther; 2018 Nov; 17(11):2285-2296. PubMed ID: 30115664
[TBL] [Abstract][Full Text] [Related]
12. Excess exogenous pyruvate inhibits lactate dehydrogenase activity in live cells in an MCT1-dependent manner.
Rao Y; Gammon ST; Sutton MN; Zacharias NM; Bhattacharya P; Piwnica-Worms D
J Biol Chem; 2021 Jul; 297(1):100775. PubMed ID: 34022218
[TBL] [Abstract][Full Text] [Related]
13. Nuclear factor E2-related factor-2 has a differential impact on MCT1 and MCT4 lactate carrier expression in colonic epithelial cells: a condition favoring metabolic symbiosis between colorectal cancer and stromal cells.
Diehl K; Dinges LA; Helm O; Ammar N; Plundrich D; Arlt A; Röcken C; Sebens S; Schäfer H
Oncogene; 2018 Jan; 37(1):39-51. PubMed ID: 28846107
[TBL] [Abstract][Full Text] [Related]
14. The SLC16 gene family - structure, role and regulation in health and disease.
Halestrap AP
Mol Aspects Med; 2013; 34(2-3):337-49. PubMed ID: 23506875
[TBL] [Abstract][Full Text] [Related]
15. Glucose deprivation increases monocarboxylate transporter 1 (MCT1) expression and MCT1-dependent tumor cell migration.
De Saedeleer CJ; Porporato PE; Copetti T; Pérez-Escuredo J; Payen VL; Brisson L; Feron O; Sonveaux P
Oncogene; 2014 Jul; 33(31):4060-8. PubMed ID: 24166504
[TBL] [Abstract][Full Text] [Related]
16. Inhibition of monocarboxyate transporter 1 by AZD3965 as a novel therapeutic approach for diffuse large B-cell lymphoma and Burkitt lymphoma.
Noble RA; Bell N; Blair H; Sikka A; Thomas H; Phillips N; Nakjang S; Miwa S; Crossland R; Rand V; Televantou D; Long A; Keun HC; Bacon CM; Bomken S; Critchlow SE; Wedge SR
Haematologica; 2017 Jul; 102(7):1247-1257. PubMed ID: 28385782
[TBL] [Abstract][Full Text] [Related]
17. A Holistic Evolutionary and 3D Pharmacophore Modelling Study Provides Insights into the Metabolism, Function, and Substrate Selectivity of the Human Monocarboxylate Transporter 4 (hMCT4).
Papakonstantinou E; Vlachakis D; Thireou T; Vlachoyiannopoulos PG; Eliopoulos E
Int J Mol Sci; 2021 Mar; 22(6):. PubMed ID: 33805725
[TBL] [Abstract][Full Text] [Related]
18. Intracellular and extracellular carbonic anhydrases cooperate non-enzymatically to enhance activity of monocarboxylate transporters.
Klier M; Andes FT; Deitmer JW; Becker HM
J Biol Chem; 2014 Jan; 289(5):2765-75. PubMed ID: 24338019
[TBL] [Abstract][Full Text] [Related]
19. Na(+)/H(+) antiporter (NHE1) and lactate/H(+) symporters (MCTs) in pH homeostasis and cancer metabolism.
Counillon L; Bouret Y; Marchiq I; Pouysségur J
Biochim Biophys Acta; 2016 Oct; 1863(10):2465-80. PubMed ID: 26944480
[TBL] [Abstract][Full Text] [Related]
20. A novel KDM5A/MPC-1 signaling pathway promotes pancreatic cancer progression via redirecting mitochondrial pyruvate metabolism.
Cui J; Quan M; Xie D; Gao Y; Guha S; Fallon MB; Chen J; Xie K
Oncogene; 2020 Jan; 39(5):1140-1151. PubMed ID: 31641207
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
