BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

215 related articles for article (PubMed ID: 29573266)

  • 41. Direct tumor lysis by NK cells uses a Ras-independent mitogen-activated protein kinase signal pathway.
    Wei S; Gilvary DL; Corliss BC; Sebti S; Sun J; Straus DB; Leibson PJ; Trapani JA; Hamilton AD; Weber MJ; Djeu JY
    J Immunol; 2000 Oct; 165(7):3811-9. PubMed ID: 11034387
    [TBL] [Abstract][Full Text] [Related]  

  • 42. Sorafenib blocks the RAF/MEK/ERK pathway, inhibits tumor angiogenesis, and induces tumor cell apoptosis in hepatocellular carcinoma model PLC/PRF/5.
    Liu L; Cao Y; Chen C; Zhang X; McNabola A; Wilkie D; Wilhelm S; Lynch M; Carter C
    Cancer Res; 2006 Dec; 66(24):11851-8. PubMed ID: 17178882
    [TBL] [Abstract][Full Text] [Related]  

  • 43. Sorafenib induces growth inhibition and apoptosis of human chondrosarcoma cells by blocking the RAF/ERK/MEK pathway.
    Lu X; Tang X; Guo W; Ren T; Zhao H
    J Surg Oncol; 2010 Dec; 102(7):821-6. PubMed ID: 20812347
    [TBL] [Abstract][Full Text] [Related]  

  • 44. Coxsackievirus B3 induces autophagy in HeLa cells via the AMPK/MEK/ERK and Ras/Raf/MEK/ERK signaling pathways.
    Xin L; Ma X; Xiao Z; Yao H; Liu Z
    Infect Genet Evol; 2015 Dec; 36():46-54. PubMed ID: 26305625
    [TBL] [Abstract][Full Text] [Related]  

  • 45. Synergy between an IGF-1R antibody and Raf/MEK/ERK and PI3K/Akt/mTOR pathway inhibitors in suppressing IGF-1R-mediated growth in hematopoietic cells.
    Bertrand FE; Steelman LS; Chappell WH; Abrams SL; Shelton JG; White ER; Ludwig DL; McCubrey JA
    Leukemia; 2006 Jul; 20(7):1254-60. PubMed ID: 16642049
    [TBL] [Abstract][Full Text] [Related]  

  • 46. Morphoproteomic profile of mTOR, Ras/Raf kinase/ERK, and NF-kappaB pathways in human gastric adenocarcinoma.
    Feng W; Brown RE; Trung CD; Li W; Wang L; Khoury T; Alrawi S; Yao J; Xia K; Tan D
    Ann Clin Lab Sci; 2008; 38(3):195-209. PubMed ID: 18715846
    [TBL] [Abstract][Full Text] [Related]  

  • 47. The Rap-B-Raf signalling pathway is activated by glucose and glucagon-like peptide-1 in human islet cells.
    Trümper J; Ross D; Jahr H; Brendel MD; Göke R; Hörsch D
    Diabetologia; 2005 Aug; 48(8):1534-40. PubMed ID: 15995848
    [TBL] [Abstract][Full Text] [Related]  

  • 48. Sorafenib (BAY 43-9006, Nexavar), a dual-action inhibitor that targets RAF/MEK/ERK pathway in tumor cells and tyrosine kinases VEGFR/PDGFR in tumor vasculature.
    Adnane L; Trail PA; Taylor I; Wilhelm SM
    Methods Enzymol; 2006; 407():597-612. PubMed ID: 16757355
    [TBL] [Abstract][Full Text] [Related]  

  • 49. LY3009120, a panRAF inhibitor, has significant anti-tumor activity in BRAF and KRAS mutant preclinical models of colorectal cancer.
    Vakana E; Pratt S; Blosser W; Dowless M; Simpson N; Yuan XJ; Jaken S; Manro J; Stephens J; Zhang Y; Huber L; Peng SB; Stancato LF
    Oncotarget; 2017 Feb; 8(6):9251-9266. PubMed ID: 27999210
    [TBL] [Abstract][Full Text] [Related]  

  • 50. Rit, a non-lipid-modified Ras-related protein, transforms NIH3T3 cells without activating the ERK, JNK, p38 MAPK or PI3K/Akt pathways.
    Rusyn EV; Reynolds ER; Shao H; Grana TM; Chan TO; Andres DA; Cox AD
    Oncogene; 2000 Sep; 19(41):4685-94. PubMed ID: 11032018
    [TBL] [Abstract][Full Text] [Related]  

  • 51. Signal transduction of MEK/ERK and PI3K/Akt activation by hypoxia/reoxygenation in renal epithelial cells.
    Kwon DS; Kwon CH; Kim JH; Woo JS; Jung JS; Kim YK
    Eur J Cell Biol; 2006 Nov; 85(11):1189-99. PubMed ID: 16860436
    [TBL] [Abstract][Full Text] [Related]  

  • 52. UL16-binding proteins, novel MHC class I-related proteins, bind to NKG2D and activate multiple signaling pathways in primary NK cells.
    Sutherland CL; Chalupny NJ; Schooley K; VandenBos T; Kubin M; Cosman D
    J Immunol; 2002 Jan; 168(2):671-9. PubMed ID: 11777960
    [TBL] [Abstract][Full Text] [Related]  

  • 53. Cooperative regulation of the cell division cycle by the protein kinases RAF and AKT.
    Mirza AM; Gysin S; Malek N; Nakayama K; Roberts JM; McMahon M
    Mol Cell Biol; 2004 Dec; 24(24):10868-81. PubMed ID: 15572689
    [TBL] [Abstract][Full Text] [Related]  

  • 54. Wogonin induces cross-regulation between autophagy and apoptosis via a variety of Akt pathway in human nasopharyngeal carcinoma cells.
    Chow SE; Chen YW; Liang CA; Huang YK; Wang JS
    J Cell Biochem; 2012 Nov; 113(11):3476-85. PubMed ID: 22689083
    [TBL] [Abstract][Full Text] [Related]  

  • 55. Effects of RAF inhibitors on PI3K/AKT signalling depend on mutational status of the RAS/RAF signalling axis.
    Fritsche-Guenther R; Witzel F; Kempa S; Brummer T; Sers C; Blüthgen N
    Oncotarget; 2016 Feb; 7(7):7960-9. PubMed ID: 26799289
    [TBL] [Abstract][Full Text] [Related]  

  • 56. α-Pinene Enhances the Anticancer Activity of Natural Killer Cells via ERK/AKT Pathway.
    Jo H; Cha B; Kim H; Brito S; Kwak BM; Kim ST; Bin BH; Lee MG
    Int J Mol Sci; 2021 Jan; 22(2):. PubMed ID: 33440866
    [TBL] [Abstract][Full Text] [Related]  

  • 57. Differential role of p38 and c-Jun N-terminal kinase 1 mitogen-activated protein kinases in NK cell cytotoxicity.
    Trotta R; Fettucciari K; Azzoni L; Abebe B; Puorro KA; Eisenlohr LC; Perussia B
    J Immunol; 2000 Aug; 165(4):1782-9. PubMed ID: 10925255
    [TBL] [Abstract][Full Text] [Related]  

  • 58. ERK mediated upregulation of death receptor 5 overcomes the lack of p53 functionality in the diaminothiazole DAT1 induced apoptosis in colon cancer models: efficiency of DAT1 in Ras-Raf mutated cells.
    Thamkachy R; Kumar R; Rajasekharan KN; Sengupta S
    Mol Cancer; 2016 Mar; 15():22. PubMed ID: 26956619
    [TBL] [Abstract][Full Text] [Related]  

  • 59. Neuroendocrine tumor cell growth inhibition by ZM336372 through alterations in multiple signaling pathways.
    Kunnimalaiyaan M; Ndiaye M; Chen H
    Surgery; 2007 Dec; 142(6):959-64; discussion 959-64. PubMed ID: 18063082
    [TBL] [Abstract][Full Text] [Related]  

  • 60. Classical RAS proteins are not essential for paradoxical ERK activation induced by RAF inhibitors.
    Lai LP; Fer N; Burgan W; Wall VE; Xu B; Soppet D; Esposito D; Nissley DV; McCormick F
    Proc Natl Acad Sci U S A; 2022 Feb; 119(5):. PubMed ID: 35091470
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 11.