BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

236 related articles for article (PubMed ID: 29575487)

  • 1. PDK1 governs thromboxane generation and thrombosis in platelets by regulating activation of Raf1 in the MAPK pathway.
    Manne BK; Münzer P; Badolia R; Walker-Allgaier B; Campbell RA; Middleton E; Weyrich AS; Kunapuli SP; Borst O; Rondina MT
    J Thromb Haemost; 2018 Jun; 16(6):1211-1225. PubMed ID: 29575487
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The small-molecule MERTK inhibitor UNC2025 decreases platelet activation and prevents thrombosis.
    Branchford BR; Stalker TJ; Law L; Acevedo G; Sather S; Brzezinski C; Wilson KM; Minson K; Lee-Sherick AB; Davizon-Castillo P; Ng C; Zhang W; Neeves KB; Lentz SR; Wang X; Frye SV; Shelton Earp H; DeRyckere D; Brass LF; Graham DK; Di Paola JA
    J Thromb Haemost; 2018 Feb; 16(2):352-363. PubMed ID: 29045015
    [TBL] [Abstract][Full Text] [Related]  

  • 3. PDK1 Determines Collagen-Dependent Platelet Ca2+ Signaling and Is Critical to Development of Ischemic Stroke In Vivo.
    Münzer P; Walker-Allgaier B; Geue S; Geuss E; Hron G; Rath D; Eißler D; Winter S; Schaeffeler E; Meinert M; Schaller M; Greinacher A; Schwab M; Geisler T; Kleinschnitz C; Lang F; Gawaz M; Borst O
    Arterioscler Thromb Vasc Biol; 2016 Aug; 36(8):1507-16. PubMed ID: 27339458
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Ginsenoside-Rp3 inhibits platelet activation and thrombus formation by regulating MAPK and cyclic nucleotide signaling.
    Irfan M; Jeong D; Kwon HW; Shin JH; Park SJ; Kwak D; Kim TH; Lee DH; Park HJ; Rhee MH
    Vascul Pharmacol; 2018 Oct; 109():45-55. PubMed ID: 29890296
    [TBL] [Abstract][Full Text] [Related]  

  • 5. PDK1 selectively phosphorylates Thr(308) on Akt and contributes to human platelet functional responses.
    Dangelmaier C; Manne BK; Liverani E; Jin J; Bray P; Kunapuli SP
    Thromb Haemost; 2014 Mar; 111(3):508-17. PubMed ID: 24352480
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Role of phosphoinositide 3-kinase beta in platelet aggregation and thromboxane A2 generation mediated by Gi signalling pathways.
    Garcia A; Kim S; Bhavaraju K; Schoenwaelder SM; Kunapuli SP
    Biochem J; 2010 Jul; 429(2):369-77. PubMed ID: 20441566
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Cross talk between serine/threonine and tyrosine kinases regulates ADP-induced thromboxane generation in platelets.
    Bhavanasi D; Badolia R; Manne BK; Janapati S; Dangelmaier CT; Mazharian A; Jin J; Kim S; Zhang X; Chen X; Senis YA; Kunapuli SP
    Thromb Haemost; 2015 Aug; 114(3):558-68. PubMed ID: 25947062
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Skepinone-L, a novel potent and highly selective inhibitor of p38 MAP kinase, effectively impairs platelet activation and thrombus formation.
    Borst O; Walker B; Münzer P; Russo A; Schmid E; Faggio C; Bigalke B; Laufer S; Gawaz M; Lang F
    Cell Physiol Biochem; 2013; 31(6):914-24. PubMed ID: 23817201
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Akt and mitogen-activated protein kinase enhance C-type lectin-like receptor 2-mediated platelet activation by inhibition of glycogen synthase kinase 3α/β.
    Moroi AJ; Watson SP
    J Thromb Haemost; 2015 Jun; 13(6):1139-50. PubMed ID: 25858425
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Differential Roles of the NADPH-Oxidase 1 and 2 in Platelet Activation and Thrombosis.
    Delaney MK; Kim K; Estevez B; Xu Z; Stojanovic-Terpo A; Shen B; Ushio-Fukai M; Cho J; Du X
    Arterioscler Thromb Vasc Biol; 2016 May; 36(5):846-54. PubMed ID: 26988594
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Phosphoinositide 3-kinase p110α negatively regulates thrombopoietin-mediated platelet activation and thrombus formation.
    Blair TA; Moore SF; Walsh TG; Hutchinson JL; Durrant TN; Anderson KE; Poole AW; Hers I
    Cell Signal; 2018 Oct; 50():111-120. PubMed ID: 29793021
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Mechanism of activation and functional role of protein kinase Ceta in human platelets.
    Bynagari YS; Nagy B; Tuluc F; Bhavaraju K; Kim S; Vijayan KV; Kunapuli SP
    J Biol Chem; 2009 May; 284(20):13413-13421. PubMed ID: 19286657
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Amyloid beta peptide-activated signal pathways in human platelets.
    Shen MY; Hsiao G; Fong TH; Chen HM; Chou DS; Lin CH; Sheu JR; Hsu CY
    Eur J Pharmacol; 2008 Jul; 588(2-3):259-66. PubMed ID: 18511035
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Extracellular cyclophilin A activates platelets via EMMPRIN (CD147) and PI3K/Akt signaling, which promotes platelet adhesion and thrombus formation in vitro and in vivo.
    Seizer P; Ungern-Sternberg SN; Schönberger T; Borst O; Münzer P; Schmidt EM; Mack AF; Heinzmann D; Chatterjee M; Langer H; Malešević M; Lang F; Gawaz M; Fischer G; May AE
    Arterioscler Thromb Vasc Biol; 2015 Mar; 35(3):655-63. PubMed ID: 25550208
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Role of Kv1.3 Channels in Platelet Functions and Thrombus Formation.
    Fan C; Yang X; Wang WW; Wang J; Li W; Guo M; Huang S; Wang Z; Liu K
    Arterioscler Thromb Vasc Biol; 2020 Oct; 40(10):2360-2375. PubMed ID: 32787516
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Two waves of platelet secretion induced by thromboxane A2 receptor and a critical role for phosphoinositide 3-kinases.
    Li Z; Zhang G; Le Breton GC; Gao X; Malik AB; Du X
    J Biol Chem; 2003 Aug; 278(33):30725-31. PubMed ID: 12796499
    [TBL] [Abstract][Full Text] [Related]  

  • 17. P2Y12 receptor-mediated potentiation of thrombin-induced thromboxane A2 generation in platelets occurs through regulation of Erk1/2 activation.
    Shankar H; Garcia A; Prabhakar J; Kim S; Kunapuli SP
    J Thromb Haemost; 2006 Mar; 4(3):638-47. PubMed ID: 16460446
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Adenosine diphosphate (ADP)-induced thromboxane A(2) generation in human platelets requires coordinated signaling through integrin alpha(IIb)beta(3) and ADP receptors.
    Jin J; Quinton TM; Zhang J; Rittenhouse SE; Kunapuli SP
    Blood; 2002 Jan; 99(1):193-8. PubMed ID: 11756171
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The protein tyrosine phosphatase PTPN7 is a negative regulator of ERK activation and thromboxane generation in platelets.
    Inamdar VV; Reddy H; Dangelmaier C; Kostyak JC; Kunapuli SP
    J Biol Chem; 2019 Aug; 294(33):12547-12554. PubMed ID: 31266805
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Regulation and functional consequences of ADP receptor-mediated ERK2 activation in platelets.
    Garcia A; Shankar H; Murugappan S; Kim S; Kunapuli SP
    Biochem J; 2007 Jun; 404(2):299-308. PubMed ID: 17298299
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.