132 related articles for article (PubMed ID: 29581770)
1. Targeting hepatocarcinogenesis model in C56BL6 mice with pan-aurora kinase inhibitor Danusertib.
Gavriilidis P; Poutahidis T; Giakoustidis A; Makedou K; Angelopoulou K; Hardas A; Andreani P; Zacharioudaki A; Saridis G; Gargavanis A; Louri E; Antoniadis N; Karampela E; Psychalakis N; Michalopoulos A; Papalois A; Iliadis S; Mudan S; Azoulay D; Giakoustidis D
J Cancer; 2018; 9(5):914-922. PubMed ID: 29581770
[No Abstract] [Full Text] [Related]
2. Hepatic B cell leukemia-3 suppresses chemically-induced hepatocarcinogenesis in mice through altered MAPK and NF-κB activation.
Gehrke N; Wörns MA; Mann A; Huber Y; Hoevelmeyer N; Longerich T; Waisman A; Galle PR; Schattenberg JM
Oncotarget; 2017 Aug; 8(34):56095-56109. PubMed ID: 28915576
[TBL] [Abstract][Full Text] [Related]
3. Danusertib, a potent pan-Aurora kinase and ABL kinase inhibitor, induces cell cycle arrest and programmed cell death and inhibits epithelial to mesenchymal transition involving the PI3K/Akt/mTOR-mediated signaling pathway in human gastric cancer AGS and NCI-N78 cells.
Yuan CX; Zhou ZW; Yang YX; He ZX; Zhang X; Wang D; Yang T; Pan SY; Chen XW; Zhou SF
Drug Des Devel Ther; 2015; 9():1293-318. PubMed ID: 25767376
[TBL] [Abstract][Full Text] [Related]
4. Targeting aurora kinases with danusertib (PHA-739358) inhibits growth of liver metastases from gastroenteropancreatic neuroendocrine tumors in an orthotopic xenograft model.
Fraedrich K; Schrader J; Ittrich H; Keller G; Gontarewicz A; Matzat V; Kromminga A; Pace A; Moll J; Bläker M; Lohse AW; Hörsch D; Brümmendorf TH; Benten D
Clin Cancer Res; 2012 Sep; 18(17):4621-32. PubMed ID: 22753592
[TBL] [Abstract][Full Text] [Related]
5. The pan-inhibitor of Aurora kinases danusertib induces apoptosis and autophagy and suppresses epithelial-to-mesenchymal transition in human breast cancer cells.
Li JP; Yang YX; Liu QL; Zhou ZW; Pan ST; He ZX; Zhang X; Yang T; Pan SY; Duan W; He SM; Chen XW; Qiu JX; Zhou SF
Drug Des Devel Ther; 2015; 9():1027-62. PubMed ID: 25733818
[TBL] [Abstract][Full Text] [Related]
6. Protein phosphatase 2A activation mechanism contributes to JS-K induced caspase-dependent apoptosis in human hepatocellular carcinoma cells.
Liu L; Huang Z; Chen J; Wang J; Wang S
J Exp Clin Cancer Res; 2018 Jul; 37(1):142. PubMed ID: 29986744
[TBL] [Abstract][Full Text] [Related]
7. Diethylnitrosamine enhances hepatic tumorigenic pathways in mice fed with high fat diet (Hfd).
Arboatti AS; Lambertucci F; Sedlmeier MG; Pisani G; Monti J; Álvarez ML; Francés DEA; Ronco MT; Carnovale CE
Chem Biol Interact; 2019 Apr; 303():70-78. PubMed ID: 30826251
[TBL] [Abstract][Full Text] [Related]
8. Caspase-3 suppresses diethylnitrosamine-induced hepatocyte death, compensatory proliferation and hepatocarcinogenesis through inhibiting p38 activation.
Shang N; Bank T; Ding X; Breslin P; Li J; Shi B; Qiu W
Cell Death Dis; 2018 May; 9(5):558. PubMed ID: 29752472
[TBL] [Abstract][Full Text] [Related]
9. Efficacy and safety of biweekly i.v. administrations of the Aurora kinase inhibitor danusertib hydrochloride in independent cohorts of patients with advanced or metastatic breast, ovarian, colorectal, pancreatic, small-cell and non-small-cell lung cancer: a multi-tumour, multi-institutional phase II study.
Schöffski P; Besse B; Gauler T; de Jonge MJ; Scambia G; Santoro A; Davite C; Jannuzzo MG; Petroccione A; Delord JP
Ann Oncol; 2015 Mar; 26(3):598-607. PubMed ID: 25488684
[TBL] [Abstract][Full Text] [Related]
10. A quantitative proteomic response of hepatocellular carcinoma Hep3B cells to danusertib, a pan-Aurora kinase inhibitor.
Zhu Q; Yu X; Zhou ZW; Luo M; Zhou C; He ZX; Chen Y; Zhou SF
J Cancer; 2018; 9(12):2061-2071. PubMed ID: 29937924
[TBL] [Abstract][Full Text] [Related]
11. Morin regulates the expression of NF-kappaB-p65, COX-2 and matrix metalloproteinases in diethylnitrosamine induced rat hepatocellular carcinoma.
Sivaramakrishnan V; Niranjali Devaraj S
Chem Biol Interact; 2009 Aug; 180(3):353-9. PubMed ID: 19539802
[TBL] [Abstract][Full Text] [Related]
12. Effects of Fas-mediated liver cell apoptosis on diethylnitrosamine-induced hepatocarcinogenesis in mice.
Hara A; Yoshimi N; Yamada Y; Matsunaga K; Kawabata K; Sugie S; Mori H
Br J Cancer; 2000 Jan; 82(2):467-71. PubMed ID: 10646906
[TBL] [Abstract][Full Text] [Related]
13. Effects of Wnt-1 blockade in DEN-induced hepatocellular adenomas of mice.
Sklavos A; Poutahidis T; Giakoustidis A; Makedou K; Angelopoulou K; Hardas A; Andreani P; Zacharioudaki A; Saridis G; Goulopoulos T; Tsarea K; Karamperi M; Papadopoulos V; Papanikolaou V; Papalois A; Iliadis S; Mudan S; Azoulay D; Giakoustidis D
Oncol Lett; 2018 Jan; 15(1):1211-1219. PubMed ID: 29399175
[TBL] [Abstract][Full Text] [Related]
14. Hepatocyte-specific activation of NF-kappaB does not aggravate chemical hepatocarcinogenesis in transgenic mice.
Yau TO; Chan CF; Gee-San Lam S; Cheung OF; Ching YP; Jin DY; Sham MH; Ng IO
J Pathol; 2009 Feb; 217(3):353-61. PubMed ID: 19090486
[TBL] [Abstract][Full Text] [Related]
15. High-saturate-fat diet delays initiation of diethylnitrosamine-induced hepatocellular carcinoma.
Duan XY; Pan Q; Yan SY; Ding WJ; Fan JG; Qiao L
BMC Gastroenterol; 2014 Nov; 14():195. PubMed ID: 25410681
[TBL] [Abstract][Full Text] [Related]
16. Influence of different pH milieu on the structure and function of human Aurora kinase B protein (AURK-B): Amalgamation of both spectroscopic and computational approach.
Gupta D; Kumari R; Kumar M; Singh M; Rawat S; Ethayathulla AS; Kaur P
Spectrochim Acta A Mol Biomol Spectrosc; 2024 May; 312():124047. PubMed ID: 38394881
[TBL] [Abstract][Full Text] [Related]
17. The Supression of Migration and Metastasis via Inhibition of Vascular Endothelial Growth Factor in Pancreatic Adenocarcinoma Cells Applied Danusertib.
Alabaş E; Ata Özçimen A
Turk J Gastroenterol; 2024 Feb; 35(2):150-157. PubMed ID: 38454247
[TBL] [Abstract][Full Text] [Related]
18. Induction of p53 renders ATM-deficient mice refractory to hepatocarcinogenesis.
Teoh N; Pyakurel P; Dan YY; Swisshelm K; Hou J; Mitchell C; Fausto N; Gu Y; Farrell G
Gastroenterology; 2010 Mar; 138(3):1155-65.e1-2. PubMed ID: 19919837
[TBL] [Abstract][Full Text] [Related]
19. Inhibition of hepatocarcinogenesis by the deletion of the p50 subunit of NF-kappaB in mice administered the peroxisome proliferator Wy-14,643.
Glauert HP; Eyigor A; Tharappel JC; Cooper S; Lee EY; Spear BT
Toxicol Sci; 2006 Apr; 90(2):331-6. PubMed ID: 16434500
[TBL] [Abstract][Full Text] [Related]
20. NADPH Oxidase 1 in Liver Macrophages Promotes Inflammation and Tumor Development in Mice.
Liang S; Ma HY; Zhong Z; Dhar D; Liu X; Xu J; Koyama Y; Nishio T; Karin D; Karin G; Mccubbin R; Zhang C; Hu R; Yang G; Chen L; Ganguly S; Lan T; Karin M; Kisseleva T; Brenner DA
Gastroenterology; 2019 Mar; 156(4):1156-1172.e6. PubMed ID: 30445007
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]