240 related articles for article (PubMed ID: 29589340)
1. Influence of Nutritional Status on the Absorption of Polyphyllin I, an Anticancer Candidate from Paris polyphylla in Rats.
Yu FL; Gong WL; Xu FJ; Wu JW; Shakya S; Zhu H
Eur J Drug Metab Pharmacokinet; 2018 Oct; 43(5):587-597. PubMed ID: 29589340
[TBL] [Abstract][Full Text] [Related]
2. Metabolic profile and pharmacokinetics of polyphyllin I, an anticancer candidate, in rats by UPLC-QTOF-MS/MS and LC-TQ-MS/MS.
Liu YC; Zhu H; Shakya S; Wu JW
Biomed Chromatogr; 2017 Mar; 31(3):. PubMed ID: 27552088
[TBL] [Abstract][Full Text] [Related]
3. Study on the pharmacokinetics profiles of polyphyllin I and its bioavailability enhancement through co-administration with P-glycoprotein inhibitors by LC-MS/MS method.
Zhu H; Zhu SC; Shakya S; Mao Q; Ding CH; Long MH; Li SL
J Pharm Biomed Anal; 2015 Mar; 107():119-24. PubMed ID: 25590941
[TBL] [Abstract][Full Text] [Related]
4. Cysteine effects on the pharmacokinetics of etoposide in protein-calorie malnutrition rats: increased gastrointestinal absorption by cysteine.
Suh JH; Kang HE; Yoon IS; Yang SH; Kim SH; Lee HJ; Shim CK; Lee MG
Xenobiotica; 2011 Oct; 41(10):885-94. PubMed ID: 21623701
[TBL] [Abstract][Full Text] [Related]
5. Application of Intestinal Epithelial Cells Differentiated from Human Induced Pluripotent Stem Cells for Studies of Prodrug Hydrolysis and Drug Absorption in the Small Intestine.
Akazawa T; Yoshida S; Ohnishi S; Kanazu T; Kawai M; Takahashi K
Drug Metab Dispos; 2018 Nov; 46(11):1497-1506. PubMed ID: 30135242
[TBL] [Abstract][Full Text] [Related]
6. The Pharmacokinetics and Tissue Distributions of Nine Steroidal Saponins from Paris polyphylla in Rats.
Lu W; Pan M; Zhang P; Zheng T; Huang L; Ye F; Lei P
Eur J Drug Metab Pharmacokinet; 2020 Oct; 45(5):665-673. PubMed ID: 32661907
[TBL] [Abstract][Full Text] [Related]
7. What kinds of substrates show P-glycoprotein-dependent intestinal absorption? Comparison of verapamil with vinblastine.
Ogihara T; Kamiya M; Ozawa M; Fujita T; Yamamoto A; Yamashita S; Ohnishi S; Isomura Y
Drug Metab Pharmacokinet; 2006 Jun; 21(3):238-44. PubMed ID: 16858128
[TBL] [Abstract][Full Text] [Related]
8. Multiple pathways are involved in the oral absorption of BMS-262084, a tryptase inhibitor, in rats: role of paracellular transport, binding to trypsin, and P-glycoprotein efflux.
Kamath AV; Morrison RA; Harper TW; Lan SJ; Marino AM; Chong S
J Pharm Sci; 2005 May; 94(5):1115-23. PubMed ID: 15793809
[TBL] [Abstract][Full Text] [Related]
9. Small intestinal efflux mediated by MRP2 and BCRP shifts sulfasalazine intestinal permeability from high to low, enabling its colonic targeting.
Dahan A; Amidon GL
Am J Physiol Gastrointest Liver Physiol; 2009 Aug; 297(2):G371-7. PubMed ID: 19541926
[TBL] [Abstract][Full Text] [Related]
10. P-glycoprotein is responsible for the poor intestinal absorption and low toxicity of oral aconitine: in vitro, in situ, in vivo and in silico studies.
Yang C; Zhang T; Li Z; Xu L; Liu F; Ruan J; Liu K; Zhang Z
Toxicol Appl Pharmacol; 2013 Dec; 273(3):561-8. PubMed ID: 24120885
[TBL] [Abstract][Full Text] [Related]
11. Simultaneous quantification of Polyphyllin D and Paris H, two potential antitumor active components in Paris polyphylla by liquid chromatography-tandem mass spectrometry and the application to pharmacokinetics in rats.
Wu S; Gao W; Qiu F; Man S; Fu S; Liu C
J Chromatogr B Analyt Technol Biomed Life Sci; 2012 Sep; 905():54-60. PubMed ID: 22917593
[TBL] [Abstract][Full Text] [Related]
12. Intestinal permeability of metformin using single-pass intestinal perfusion in rats.
Song NN; Li QS; Liu CX
World J Gastroenterol; 2006 Jul; 12(25):4064-70. PubMed ID: 16810761
[TBL] [Abstract][Full Text] [Related]
13. P-glycoprotein expression in the gastrointestinal tract of male and female rats is influenced differently by food.
Dou L; Mai Y; Madla CM; Orlu M; Basit AW
Eur J Pharm Sci; 2018 Oct; 123():569-575. PubMed ID: 30118850
[TBL] [Abstract][Full Text] [Related]
14. Montmorillonite-surfactant hybrid particles for modulating intestinal P-glycoprotein-mediated transport.
Nielsen RB; Kahnt A; Dillen L; Wuyts K; Snoeys J; Nielsen UG; Holm R; Nielsen CU
Int J Pharm; 2019 Nov; 571():118696. PubMed ID: 31525443
[TBL] [Abstract][Full Text] [Related]
15. Segmental dependent transport of low permeability compounds along the small intestine due to P-glycoprotein: the role of efflux transport in the oral absorption of BCS class III drugs.
Dahan A; Amidon GL
Mol Pharm; 2009; 6(1):19-28. PubMed ID: 19248230
[TBL] [Abstract][Full Text] [Related]
16. Commonly used surfactant, Tween 80, improves absorption of P-glycoprotein substrate, digoxin, in rats.
Zhang H; Yao M; Morrison RA; Chong S
Arch Pharm Res; 2003 Sep; 26(9):768-72. PubMed ID: 14560928
[TBL] [Abstract][Full Text] [Related]
17. Effect of hydroxyzine on the transport of etoposide in rat small intestine.
Kan WM; Liu YT; Hsiao CL; Shieh CY; Kuo JH; Huang JD; Su SF
Anticancer Drugs; 2001 Mar; 12(3):267-73. PubMed ID: 11290874
[TBL] [Abstract][Full Text] [Related]
18. Molecular mechanisms of Polyphyllin I-induced apoptosis and reversal of the epithelial-mesenchymal transition in human osteosarcoma cells.
Chang J; Wang H; Wang X; Zhao Y; Zhao D; Wang C; Li Y; Yang Z; Lu S; Zeng Q; Zimmerman J; Shi Q; Wang Y; Yang Y
J Ethnopharmacol; 2015 Jul; 170():117-27. PubMed ID: 25978954
[TBL] [Abstract][Full Text] [Related]
19. Anti-cancer effects of Polyphyllin I: An update in 5 years.
Tian Y; Gong GY; Ma LL; Wang ZQ; Song D; Fang MY
Chem Biol Interact; 2020 Jan; 316():108936. PubMed ID: 31870841
[TBL] [Abstract][Full Text] [Related]
20. Baicalin reduces ciclosporin bioavailability by inducing intestinal p-glycoprotein in rats.
Tian X; Chang Y; Wei J; Liu R; Wang L; Zhang J; Zhang X
J Pharm Pharmacol; 2019 May; 71(5):788-796. PubMed ID: 30663770
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
