478 related articles for article (PubMed ID: 29600961)
21. Opposing effects of viral mediated brain expression of apolipoprotein E2 (apoE2) and apoE4 on apoE lipidation and Aβ metabolism in apoE4-targeted replacement mice.
Hu J; Liu CC; Chen XF; Zhang YW; Xu H; Bu G
Mol Neurodegener; 2015 Mar; 10():6. PubMed ID: 25871773
[TBL] [Abstract][Full Text] [Related]
22. APOE4-specific changes in Aβ accumulation in a new transgenic mouse model of Alzheimer disease.
Youmans KL; Tai LM; Nwabuisi-Heath E; Jungbauer L; Kanekiyo T; Gan M; Kim J; Eimer WA; Estus S; Rebeck GW; Weeber EJ; Bu G; Yu C; Ladu MJ
J Biol Chem; 2012 Dec; 287(50):41774-86. PubMed ID: 23060451
[TBL] [Abstract][Full Text] [Related]
23. APOE3, but not APOE4, bone marrow transplantation mitigates behavioral and pathological changes in a mouse model of Alzheimer disease.
Yang Y; Cudaback E; Jorstad NL; Hemingway JF; Hagan CE; Melief EJ; Li X; Yoo T; Khademi SB; Montine KS; Montine TJ; Keene CD
Am J Pathol; 2013 Sep; 183(3):905-17. PubMed ID: 23831297
[TBL] [Abstract][Full Text] [Related]
24. Intraneuronal amyloid-beta plays a role in mediating the synergistic pathological effects of apoE4 and environmental stimulation.
Levi O; Dolev I; Belinson H; Michaelson DM
J Neurochem; 2007 Nov; 103(3):1031-40. PubMed ID: 17666042
[TBL] [Abstract][Full Text] [Related]
25. Impaired Autophagy in APOE4 Astrocytes.
Simonovitch S; Schmukler E; Bespalko A; Iram T; Frenkel D; Holtzman DM; Masliah E; Michaelson DM; Pinkas-Kramarski R
J Alzheimers Dis; 2016; 51(3):915-27. PubMed ID: 26923027
[TBL] [Abstract][Full Text] [Related]
26. Inhibition of ACAT as a Therapeutic Target for Alzheimer's Disease Is Independent of ApoE4 Lipidation.
Valencia-Olvera AC; Balu D; Faulk N; Amiridis A; Wang Y; Pham C; Avila-Munoz E; York JM; Thatcher GRJ; LaDu MJ
Neurotherapeutics; 2023 Jul; 20(4):1120-1137. PubMed ID: 37157042
[TBL] [Abstract][Full Text] [Related]
27. Cell-autonomous effects of APOE4 in restricting microglial response in brain homeostasis and Alzheimer's disease.
Liu CC; Wang N; Chen Y; Inoue Y; Shue F; Ren Y; Wang M; Qiao W; Ikezu TC; Li Z; Zhao J; Martens Y; Doss SV; Rosenberg CL; Jeevaratnam S; Jia L; Raulin AC; Qi F; Zhu Y; Alnobani A; Knight J; Chen Y; Linares C; Kurti A; Fryer JD; Zhang B; Wu LJ; Kim BYS; Bu G
Nat Immunol; 2023 Nov; 24(11):1854-1866. PubMed ID: 37857825
[TBL] [Abstract][Full Text] [Related]
28. Apolipoprotein E4 inhibits γ-secretase activity via binding to the γ-secretase complex.
Sun Y; Islam S; Gao Y; Nakamura T; Zou K; Michikawa M
J Neurochem; 2023 Mar; 164(6):858-874. PubMed ID: 36582176
[TBL] [Abstract][Full Text] [Related]
29. Temporal Characterization of the Amyloidogenic APPswe/PS1dE9;hAPOE4 Mouse Model of Alzheimer's Disease.
Grenon MB; Papavergi MT; Bathini P; Sadowski M; Lemere CA
Int J Mol Sci; 2024 May; 25(11):. PubMed ID: 38891941
[TBL] [Abstract][Full Text] [Related]
30. Soluble apoE/Aβ complex: mechanism and therapeutic target for APOE4-induced AD risk.
Tai LM; Mehra S; Shete V; Estus S; Rebeck GW; Bu G; LaDu MJ
Mol Neurodegener; 2014 Jan; 9():2. PubMed ID: 24386905
[TBL] [Abstract][Full Text] [Related]
31. High ability of apolipoprotein E4 to stabilize amyloid-β peptide oligomers, the pathological entities responsible for Alzheimer's disease.
Cerf E; Gustot A; Goormaghtigh E; Ruysschaert JM; Raussens V
FASEB J; 2011 May; 25(5):1585-95. PubMed ID: 21266538
[TBL] [Abstract][Full Text] [Related]
32. Apolipoprotein E4 influences amyloid deposition but not cell loss after traumatic brain injury in a mouse model of Alzheimer's disease.
Hartman RE; Laurer H; Longhi L; Bales KR; Paul SM; McIntosh TK; Holtzman DM
J Neurosci; 2002 Dec; 22(23):10083-7. PubMed ID: 12451108
[TBL] [Abstract][Full Text] [Related]
33. Differential Signaling Mediated by ApoE2, ApoE3, and ApoE4 in Human Neurons Parallels Alzheimer's Disease Risk.
Huang YA; Zhou B; Nabet AM; Wernig M; Südhof TC
J Neurosci; 2019 Sep; 39(37):7408-7427. PubMed ID: 31331998
[TBL] [Abstract][Full Text] [Related]
34. Murine versus human apolipoprotein E4: differential facilitation of and co-localization in cerebral amyloid angiopathy and amyloid plaques in APP transgenic mouse models.
Liao F; Zhang TJ; Jiang H; Lefton KB; Robinson GO; Vassar R; Sullivan PM; Holtzman DM
Acta Neuropathol Commun; 2015 Nov; 3():70. PubMed ID: 26556230
[TBL] [Abstract][Full Text] [Related]
35. Levels of soluble apolipoprotein E/amyloid-β (Aβ) complex are reduced and oligomeric Aβ increased with APOE4 and Alzheimer disease in a transgenic mouse model and human samples.
Tai LM; Bilousova T; Jungbauer L; Roeske SK; Youmans KL; Yu C; Poon WW; Cornwell LB; Miller CA; Vinters HV; Van Eldik LJ; Fardo DW; Estus S; Bu G; Gylys KH; Ladu MJ
J Biol Chem; 2013 Feb; 288(8):5914-26. PubMed ID: 23293020
[TBL] [Abstract][Full Text] [Related]
36. APOE effects on regional tau in preclinical Alzheimer's disease.
Young CB; Johns E; Kennedy G; Belloy ME; Insel PS; Greicius MD; Sperling RA; Johnson KA; Poston KL; Mormino EC; ;
Mol Neurodegener; 2023 Jan; 18(1):1. PubMed ID: 36597122
[TBL] [Abstract][Full Text] [Related]
37. Anti-ApoE antibody given after plaque onset decreases Aβ accumulation and improves brain function in a mouse model of Aβ amyloidosis.
Liao F; Hori Y; Hudry E; Bauer AQ; Jiang H; Mahan TE; Lefton KB; Zhang TJ; Dearborn JT; Kim J; Culver JP; Betensky R; Wozniak DF; Hyman BT; Holtzman DM
J Neurosci; 2014 May; 34(21):7281-92. PubMed ID: 24849360
[TBL] [Abstract][Full Text] [Related]
38. Reducing human apolipoprotein E levels attenuates age-dependent Aβ accumulation in mutant human amyloid precursor protein transgenic mice.
Bien-Ly N; Gillespie AK; Walker D; Yoon SY; Huang Y
J Neurosci; 2012 Apr; 32(14):4803-11. PubMed ID: 22492035
[TBL] [Abstract][Full Text] [Related]
39. Astrocytic APOE4 removal confers cerebrovascular protection despite increased cerebral amyloid angiopathy.
Xiong M; Wang C; Gratuze M; Saadi F; Bao X; Bosch ME; Lee C; Jiang H; Serrano JR; Gonzales ER; Kipnis M; Holtzman DM
Mol Neurodegener; 2023 Mar; 18(1):17. PubMed ID: 36922879
[TBL] [Abstract][Full Text] [Related]
40. APOE genotype and sex affect microglial interactions with plaques in Alzheimer's disease mice.
Stephen TL; Cacciottolo M; Balu D; Morgan TE; LaDu MJ; Finch CE; Pike CJ
Acta Neuropathol Commun; 2019 May; 7(1):82. PubMed ID: 31113487
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
