These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

615 related articles for article (PubMed ID: 29602020)

  • 1. Mimicking brain tissue binding in an in vitro model of the blood-brain barrier illustrates differences between in vitro and in vivo methods for assessing the rate of brain penetration.
    Heymans M; Sevin E; Gosselet F; Lundquist S; Culot M
    Eur J Pharm Biopharm; 2018 Jun; 127():453-461. PubMed ID: 29602020
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Application of an in Vitro Blood-Brain Barrier Model in the Selection of Experimental Drug Candidates for the Treatment of Huntington's Disease.
    Di Marco A; Gonzalez Paz O; Fini I; Vignone D; Cellucci A; Battista MR; Auciello G; Orsatti L; Zini M; Monteagudo E; Khetarpal V; Rose M; Dominguez C; Herbst T; Toledo-Sherman L; Summa V; Muñoz-Sanjuán I
    Mol Pharm; 2019 May; 16(5):2069-2082. PubMed ID: 30916978
    [TBL] [Abstract][Full Text] [Related]  

  • 3. In vitro porcine blood-brain barrier model for permeability studies: pCEL-X software pKa(FLUX) method for aqueous boundary layer correction and detailed data analysis.
    Yusof SR; Avdeef A; Abbott NJ
    Eur J Pharm Sci; 2014 Dec; 65():98-111. PubMed ID: 25239510
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Porcine brain microvessel endothelial cells as an in vitro model to predict in vivo blood-brain barrier permeability.
    Zhang Y; Li CS; Ye Y; Johnson K; Poe J; Johnson S; Bobrowski W; Garrido R; Madhu C
    Drug Metab Dispos; 2006 Nov; 34(11):1935-43. PubMed ID: 16896068
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Integrating in Silico and in Vitro Approaches To Predict Drug Accessibility to the Central Nervous System.
    Zhang YY; Liu H; Summerfield SG; Luscombe CN; Sahi J
    Mol Pharm; 2016 May; 13(5):1540-50. PubMed ID: 27015243
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Blood-brain barrier models: in vitro to in vivo translation in preclinical development of CNS-targeting biotherapeutics.
    Stanimirovic DB; Bani-Yaghoub M; Perkins M; Haqqani AS
    Expert Opin Drug Discov; 2015 Feb; 10(2):141-55. PubMed ID: 25388782
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Validation of in vitro cell-based human blood-brain barrier model using clinical positron emission tomography radioligands to predict in vivo human brain penetration.
    Mabondzo A; Bottlaender M; Guyot AC; Tsaouin K; Deverre JR; Balimane PV
    Mol Pharm; 2010 Oct; 7(5):1805-15. PubMed ID: 20795735
    [TBL] [Abstract][Full Text] [Related]  

  • 8. In vitro primary human and animal cell-based blood-brain barrier models as a screening tool in drug discovery.
    Lacombe O; Videau O; Chevillon D; Guyot AC; Contreras C; Blondel S; Nicolas L; Ghettas A; Bénech H; Thevenot E; Pruvost A; Bolze S; Krzaczkowski L; Prévost C; Mabondzo A
    Mol Pharm; 2011 Jun; 8(3):651-63. PubMed ID: 21438632
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Prediction of drug transport through the blood-brain barrier in vivo: a comparison between two in vitro cell models.
    Lundquist S; Renftel M; Brillault J; Fenart L; Cecchelli R; Dehouck MP
    Pharm Res; 2002 Jul; 19(7):976-81. PubMed ID: 12180550
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A Human Immortalized Cell-Based Blood-Brain Barrier Triculture Model: Development and Characterization as a Promising Tool for Drug-Brain Permeability Studies.
    Ito R; Umehara K; Suzuki S; Kitamura K; Nunoya KI; Yamaura Y; Imawaka H; Izumi S; Wakayama N; Komori T; Anzai N; Akita H; Furihata T
    Mol Pharm; 2019 Nov; 16(11):4461-4471. PubMed ID: 31573814
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Comparison of blood-brain barrier permeability assays: in situ brain perfusion, MDR1-MDCKII and PAMPA-BBB.
    Di L; Kerns EH; Bezar IF; Petusky SL; Huang Y
    J Pharm Sci; 2009 Jun; 98(6):1980-91. PubMed ID: 18837012
    [TBL] [Abstract][Full Text] [Related]  

  • 12. In-vitro blood-brain barrier models for drug screening and permeation studies: an overview.
    Bagchi S; Chhibber T; Lahooti B; Verma A; Borse V; Jayant RD
    Drug Des Devel Ther; 2019; 13():3591-3605. PubMed ID: 31695329
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Evaluation of drug penetration into the brain: a double study by in vivo imaging with positron emission tomography and using an in vitro model of the human blood-brain barrier.
    Josserand V; Pélerin H; de Bruin B; Jego B; Kuhnast B; Hinnen F; Ducongé F; Boisgard R; Beuvon F; Chassoux F; Daumas-Duport C; Ezan E; Dollé F; Mabondzo A; Tavitian B
    J Pharmacol Exp Ther; 2006 Jan; 316(1):79-86. PubMed ID: 16210395
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Similar molecular descriptors determine the in vitro drug permeability in endothelial and epithelial cells.
    Hakkarainen JJ; Pajander J; Laitinen R; Suhonen M; Forsberg MM
    Int J Pharm; 2012 Oct; 436(1-2):426-43. PubMed ID: 22750947
    [TBL] [Abstract][Full Text] [Related]  

  • 15. In vitro models for the blood-brain barrier.
    Garberg P; Ball M; Borg N; Cecchelli R; Fenart L; Hurst RD; Lindmark T; Mabondzo A; Nilsson JE; Raub TJ; Stanimirovic D; Terasaki T; Oberg JO; Osterberg T
    Toxicol In Vitro; 2005 Apr; 19(3):299-334. PubMed ID: 15713540
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A new PAMPA model using an in-house brain lipid extract for screening the blood-brain barrier permeability of drug candidates.
    Bicker J; Alves G; Fortuna A; Soares-da-Silva P; Falcão A
    Int J Pharm; 2016 Mar; 501(1-2):102-11. PubMed ID: 26836708
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Microfluidic blood-brain barrier model provides in vivo-like barrier properties for drug permeability screening.
    Wang YI; Abaci HE; Shuler ML
    Biotechnol Bioeng; 2017 Jan; 114(1):184-194. PubMed ID: 27399645
    [TBL] [Abstract][Full Text] [Related]  

  • 18. In vitro models of the blood-brain barrier for the study of drug delivery to the brain.
    Wilhelm I; Krizbai IA
    Mol Pharm; 2014 Jul; 11(7):1949-63. PubMed ID: 24641309
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Evaluation of the MDR-MDCK cell line as a permeability screen for the blood-brain barrier.
    Wang Q; Rager JD; Weinstein K; Kardos PS; Dobson GL; Li J; Hidalgo IJ
    Int J Pharm; 2005 Jan; 288(2):349-59. PubMed ID: 15620875
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Zebrafish: A promising in vivo model for assessing the delivery of natural products, fluorescence dyes and drugs across the blood-brain barrier.
    Li Y; Chen T; Miao X; Yi X; Wang X; Zhao H; Lee SM; Zheng Y
    Pharmacol Res; 2017 Nov; 125(Pt B):246-257. PubMed ID: 28867638
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 31.