614 related articles for article (PubMed ID: 29602020)
1. Mimicking brain tissue binding in an in vitro model of the blood-brain barrier illustrates differences between in vitro and in vivo methods for assessing the rate of brain penetration.
Heymans M; Sevin E; Gosselet F; Lundquist S; Culot M
Eur J Pharm Biopharm; 2018 Jun; 127():453-461. PubMed ID: 29602020
[TBL] [Abstract][Full Text] [Related]
2. Application of an in Vitro Blood-Brain Barrier Model in the Selection of Experimental Drug Candidates for the Treatment of Huntington's Disease.
Di Marco A; Gonzalez Paz O; Fini I; Vignone D; Cellucci A; Battista MR; Auciello G; Orsatti L; Zini M; Monteagudo E; Khetarpal V; Rose M; Dominguez C; Herbst T; Toledo-Sherman L; Summa V; Muñoz-Sanjuán I
Mol Pharm; 2019 May; 16(5):2069-2082. PubMed ID: 30916978
[TBL] [Abstract][Full Text] [Related]
3. In vitro porcine blood-brain barrier model for permeability studies: pCEL-X software pKa(FLUX) method for aqueous boundary layer correction and detailed data analysis.
Yusof SR; Avdeef A; Abbott NJ
Eur J Pharm Sci; 2014 Dec; 65():98-111. PubMed ID: 25239510
[TBL] [Abstract][Full Text] [Related]
4. Porcine brain microvessel endothelial cells as an in vitro model to predict in vivo blood-brain barrier permeability.
Zhang Y; Li CS; Ye Y; Johnson K; Poe J; Johnson S; Bobrowski W; Garrido R; Madhu C
Drug Metab Dispos; 2006 Nov; 34(11):1935-43. PubMed ID: 16896068
[TBL] [Abstract][Full Text] [Related]
5. Integrating in Silico and in Vitro Approaches To Predict Drug Accessibility to the Central Nervous System.
Zhang YY; Liu H; Summerfield SG; Luscombe CN; Sahi J
Mol Pharm; 2016 May; 13(5):1540-50. PubMed ID: 27015243
[TBL] [Abstract][Full Text] [Related]
6. Blood-brain barrier models: in vitro to in vivo translation in preclinical development of CNS-targeting biotherapeutics.
Stanimirovic DB; Bani-Yaghoub M; Perkins M; Haqqani AS
Expert Opin Drug Discov; 2015 Feb; 10(2):141-55. PubMed ID: 25388782
[TBL] [Abstract][Full Text] [Related]
7. Validation of in vitro cell-based human blood-brain barrier model using clinical positron emission tomography radioligands to predict in vivo human brain penetration.
Mabondzo A; Bottlaender M; Guyot AC; Tsaouin K; Deverre JR; Balimane PV
Mol Pharm; 2010 Oct; 7(5):1805-15. PubMed ID: 20795735
[TBL] [Abstract][Full Text] [Related]
8. In vitro primary human and animal cell-based blood-brain barrier models as a screening tool in drug discovery.
Lacombe O; Videau O; Chevillon D; Guyot AC; Contreras C; Blondel S; Nicolas L; Ghettas A; Bénech H; Thevenot E; Pruvost A; Bolze S; Krzaczkowski L; Prévost C; Mabondzo A
Mol Pharm; 2011 Jun; 8(3):651-63. PubMed ID: 21438632
[TBL] [Abstract][Full Text] [Related]
9. Prediction of drug transport through the blood-brain barrier in vivo: a comparison between two in vitro cell models.
Lundquist S; Renftel M; Brillault J; Fenart L; Cecchelli R; Dehouck MP
Pharm Res; 2002 Jul; 19(7):976-81. PubMed ID: 12180550
[TBL] [Abstract][Full Text] [Related]
10. A Human Immortalized Cell-Based Blood-Brain Barrier Triculture Model: Development and Characterization as a Promising Tool for Drug-Brain Permeability Studies.
Ito R; Umehara K; Suzuki S; Kitamura K; Nunoya KI; Yamaura Y; Imawaka H; Izumi S; Wakayama N; Komori T; Anzai N; Akita H; Furihata T
Mol Pharm; 2019 Nov; 16(11):4461-4471. PubMed ID: 31573814
[TBL] [Abstract][Full Text] [Related]
11. In-vitro blood-brain barrier models for drug screening and permeation studies: an overview.
Bagchi S; Chhibber T; Lahooti B; Verma A; Borse V; Jayant RD
Drug Des Devel Ther; 2019; 13():3591-3605. PubMed ID: 31695329
[TBL] [Abstract][Full Text] [Related]
12. Comparison of blood-brain barrier permeability assays: in situ brain perfusion, MDR1-MDCKII and PAMPA-BBB.
Di L; Kerns EH; Bezar IF; Petusky SL; Huang Y
J Pharm Sci; 2009 Jun; 98(6):1980-91. PubMed ID: 18837012
[TBL] [Abstract][Full Text] [Related]
13. Evaluation of drug penetration into the brain: a double study by in vivo imaging with positron emission tomography and using an in vitro model of the human blood-brain barrier.
Josserand V; Pélerin H; de Bruin B; Jego B; Kuhnast B; Hinnen F; Ducongé F; Boisgard R; Beuvon F; Chassoux F; Daumas-Duport C; Ezan E; Dollé F; Mabondzo A; Tavitian B
J Pharmacol Exp Ther; 2006 Jan; 316(1):79-86. PubMed ID: 16210395
[TBL] [Abstract][Full Text] [Related]
14. Similar molecular descriptors determine the in vitro drug permeability in endothelial and epithelial cells.
Hakkarainen JJ; Pajander J; Laitinen R; Suhonen M; Forsberg MM
Int J Pharm; 2012 Oct; 436(1-2):426-43. PubMed ID: 22750947
[TBL] [Abstract][Full Text] [Related]
15. In vitro models for the blood-brain barrier.
Garberg P; Ball M; Borg N; Cecchelli R; Fenart L; Hurst RD; Lindmark T; Mabondzo A; Nilsson JE; Raub TJ; Stanimirovic D; Terasaki T; Oberg JO; Osterberg T
Toxicol In Vitro; 2005 Apr; 19(3):299-334. PubMed ID: 15713540
[TBL] [Abstract][Full Text] [Related]
16. A new PAMPA model using an in-house brain lipid extract for screening the blood-brain barrier permeability of drug candidates.
Bicker J; Alves G; Fortuna A; Soares-da-Silva P; Falcão A
Int J Pharm; 2016 Mar; 501(1-2):102-11. PubMed ID: 26836708
[TBL] [Abstract][Full Text] [Related]
17. Microfluidic blood-brain barrier model provides in vivo-like barrier properties for drug permeability screening.
Wang YI; Abaci HE; Shuler ML
Biotechnol Bioeng; 2017 Jan; 114(1):184-194. PubMed ID: 27399645
[TBL] [Abstract][Full Text] [Related]
18. In vitro models of the blood-brain barrier for the study of drug delivery to the brain.
Wilhelm I; Krizbai IA
Mol Pharm; 2014 Jul; 11(7):1949-63. PubMed ID: 24641309
[TBL] [Abstract][Full Text] [Related]
19. Evaluation of the MDR-MDCK cell line as a permeability screen for the blood-brain barrier.
Wang Q; Rager JD; Weinstein K; Kardos PS; Dobson GL; Li J; Hidalgo IJ
Int J Pharm; 2005 Jan; 288(2):349-59. PubMed ID: 15620875
[TBL] [Abstract][Full Text] [Related]
20. Zebrafish: A promising in vivo model for assessing the delivery of natural products, fluorescence dyes and drugs across the blood-brain barrier.
Li Y; Chen T; Miao X; Yi X; Wang X; Zhao H; Lee SM; Zheng Y
Pharmacol Res; 2017 Nov; 125(Pt B):246-257. PubMed ID: 28867638
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
