These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

615 related articles for article (PubMed ID: 29602020)

  • 21. Studies of blood-brain barrier permeability of gastrodigenin in vitro and in vivo.
    Mi Y; Mao Y; Cheng H; Ke G; Liu M; Fang C; Wang Q
    Fitoterapia; 2020 Jan; 140():104447. PubMed ID: 31805306
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Addressing central nervous system (CNS) penetration in drug discovery: basics and implications of the evolving new concept.
    Reichel A
    Chem Biodivers; 2009 Nov; 6(11):2030-49. PubMed ID: 19937839
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Blood-brain barrier models and their relevance for a successful development of CNS drug delivery systems: a review.
    Bicker J; Alves G; Fortuna A; Falcão A
    Eur J Pharm Biopharm; 2014 Aug; 87(3):409-32. PubMed ID: 24686194
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Comparison of in vitro BBMEC permeability and in vivo CNS uptake by microdialysis sampling.
    Hansen DK; Scott DO; Otis KW; Lunte SM
    J Pharm Biomed Anal; 2002 Mar; 27(6):945-58. PubMed ID: 11836058
    [TBL] [Abstract][Full Text] [Related]  

  • 25. The grasshopper: a novel model for assessing vertebrate brain uptake.
    Andersson O; Hansen SH; Hellman K; Olsen LR; Andersson G; Badolo L; Svenstrup N; Nielsen PA
    J Pharmacol Exp Ther; 2013 Aug; 346(2):211-8. PubMed ID: 23671124
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Physicochemical selectivity of the BBB microenvironment governing passive diffusion--matching with a porcine brain lipid extract artificial membrane permeability model.
    Tsinman O; Tsinman K; Sun N; Avdeef A
    Pharm Res; 2011 Feb; 28(2):337-63. PubMed ID: 20945153
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Case study: adapting in vitro blood-brain barrier models for use in early-stage drug discovery.
    Vandenhaute E; Sevin E; Hallier-Vanuxeem D; Dehouck MP; Cecchelli R
    Drug Discov Today; 2012 Apr; 17(7-8):285-90. PubMed ID: 22033197
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Analysing molecular polar surface descriptors to predict blood-brain barrier permeation.
    Shityakov S; Neuhaus W; Dandekar T; Förster C
    Int J Comput Biol Drug Des; 2013; 6(1-2):146-56. PubMed ID: 23428480
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Application of in vitro PAMPA technique and in silico computational methods for blood-brain barrier permeability prediction of novel CNS drug candidates.
    Radan M; Djikic T; Obradovic D; Nikolic K
    Eur J Pharm Sci; 2022 Jan; 168():106056. PubMed ID: 34740787
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Comparison of brain capillary endothelial cell-based and epithelial (MDCK-MDR1, Caco-2, and VB-Caco-2) cell-based surrogate blood-brain barrier penetration models.
    Hellinger E; Veszelka S; Tóth AE; Walter F; Kittel A; Bakk ML; Tihanyi K; Háda V; Nakagawa S; Duy TD; Niwa M; Deli MA; Vastag M
    Eur J Pharm Biopharm; 2012 Oct; 82(2):340-51. PubMed ID: 22906709
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Blood-brain barrier endogenous transporters as therapeutic targets: a new model for small molecule CNS drug discovery.
    Pardridge WM
    Expert Opin Ther Targets; 2015; 19(8):1059-72. PubMed ID: 25936389
    [TBL] [Abstract][Full Text] [Related]  

  • 32. In vitro blood-brain barrier models using brain capillary endothelial cells isolated from neonatal and adult rats retain age-related barrier properties.
    Takata F; Dohgu S; Yamauchi A; Matsumoto J; Machida T; Fujishita K; Shibata K; Shinozaki Y; Sato K; Kataoka Y; Koizumi S
    PLoS One; 2013; 8(1):e55166. PubMed ID: 23383092
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Development and validation of a LC-MS/MS method for assessment of an anti-inflammatory indolinone derivative by in vitro blood-brain barrier models.
    Jähne EA; Eigenmann DE; Culot M; Cecchelli R; Walter FR; Deli MA; Tremmel R; Fricker G; Smiesko M; Hamburger M; Oufir M
    J Pharm Biomed Anal; 2014 Sep; 98():235-46. PubMed ID: 24949819
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Innovative in vitro method to predict rate and extent of drug delivery to the brain across the blood-brain barrier.
    Mangas-Sanjuan V; González-Álvarez I; González-Álvarez M; Casabó VG; Bermejo M
    Mol Pharm; 2013 Oct; 10(10):3822-31. PubMed ID: 23977999
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Assessment of the Blood-Brain Barrier Permeability of Potential Neuroprotective Aurones in Parallel Artificial Membrane Permeability Assay and Porcine Brain Endothelial Cell Models.
    Liew KF; Hanapi NA; Chan KL; Yusof SR; Lee CY
    J Pharm Sci; 2017 Feb; 106(2):502-510. PubMed ID: 27855959
    [TBL] [Abstract][Full Text] [Related]  

  • 36. How well can in vitro brain microcapillary endothelial cell models predict rodent in vivo blood-brain barrier permeability?
    Avdeef A
    Eur J Pharm Sci; 2011 Jun; 43(3):109-24. PubMed ID: 21514381
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Learning from our failures in blood-brain permeability: what can be done for new drug discovery?
    Martel S
    Expert Opin Drug Discov; 2015 Mar; 10(3):207-11. PubMed ID: 25658294
    [TBL] [Abstract][Full Text] [Related]  

  • 38. In Vitro-In Vivo Correlation of Blood-Brain Barrier Permeability of Drugs: A Feasibility Study Towards Development of Prediction Methods for Brain Drug Concentration in Humans.
    Ito R; Morio H; Baba T; Sakaguchi Y; Wakayama N; Isogai R; Yamaura Y; Komori T; Furihata T
    Pharm Res; 2022 Jul; 39(7):1575-1586. PubMed ID: 35288803
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Progress in brain penetration evaluation in drug discovery and development.
    Liu X; Chen C; Smith BJ
    J Pharmacol Exp Ther; 2008 May; 325(2):349-56. PubMed ID: 18203948
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Hurdles with using in vitro models to predict human blood-brain barrier drug permeability: a special focus on transporters and metabolizing enzymes.
    Shawahna R; Decleves X; Scherrmann JM
    Curr Drug Metab; 2013 Jan; 14(1):120-36. PubMed ID: 23215812
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 31.