BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

278 related articles for article (PubMed ID: 29602039)

  • 41. Overview of AKR1C3: Inhibitor Achievements and Disease Insights.
    Liu Y; He S; Chen Y; Liu Y; Feng F; Liu W; Guo Q; Zhao L; Sun H
    J Med Chem; 2020 Oct; 63(20):11305-11329. PubMed ID: 32463235
    [TBL] [Abstract][Full Text] [Related]  

  • 42. Type 5 17beta-hydroxysteroid dehydrogenase/prostaglandin F synthase (AKR1C3): role in breast cancer and inhibition by non-steroidal anti-inflammatory drug analogs.
    Byrns MC; Penning TM
    Chem Biol Interact; 2009 Mar; 178(1-3):221-7. PubMed ID: 19010312
    [TBL] [Abstract][Full Text] [Related]  

  • 43. Novel aldo-keto reductase 1C3 inhibitor affects androgen metabolism but not ovarian function in healthy women: a phase 1 study.
    Gashaw I; Reif S; Wiesinger H; Kaiser A; Zollmann FS; Scheerans C; Grevel J; Piraino P; Seidel H; Peters M; Rottmann A; Rohde B; Arlt W; Hilpert J
    Eur J Endocrinol; 2023 Jul; 188(7):578-591. PubMed ID: 37306288
    [TBL] [Abstract][Full Text] [Related]  

  • 44. AKR1C3 as a target in castrate resistant prostate cancer.
    Adeniji AO; Chen M; Penning TM
    J Steroid Biochem Mol Biol; 2013 Sep; 137():136-49. PubMed ID: 23748150
    [TBL] [Abstract][Full Text] [Related]  

  • 45. Inhibitors of type 5 17β-hydroxysteroid dehydrogenase (AKR1C3): overview and structural insights.
    Byrns MC; Jin Y; Penning TM
    J Steroid Biochem Mol Biol; 2011 May; 125(1-2):95-104. PubMed ID: 21087665
    [TBL] [Abstract][Full Text] [Related]  

  • 46. Nonsteroidal anti-inflammatory drugs and their analogues as inhibitors of aldo-keto reductase AKR1C3: new lead compounds for the development of anticancer agents.
    Gobec S; Brozic P; Rizner TL
    Bioorg Med Chem Lett; 2005 Dec; 15(23):5170-5. PubMed ID: 16183274
    [TBL] [Abstract][Full Text] [Related]  

  • 47. Aldo-Keto Reductase 1C3 Inhibitor Prodrug Improves Pharmacokinetic Profile and Demonstrates In Vivo Efficacy in a Prostate Cancer Xenograft Model.
    Maddeboina K; Jonnalagadda SK; Morsy A; Duan L; Chhonker YS; Murry DJ; Penning TM; Trippier PC
    J Med Chem; 2023 Jul; 66(14):9894-9915. PubMed ID: 37428858
    [TBL] [Abstract][Full Text] [Related]  

  • 48. Development of Biaryl-Containing Aldo-Keto Reductase 1C3 (AKR1C3) Inhibitors for Reversing AKR1C3-Mediated Drug Resistance in Cancer Treatment.
    He S; Chu X; Wu Y; Jiang J; Fang P; Chen Y; Liu Y; Qiu Z; Xiao Y; Li Z; Pan D; Zhang Q; Xie H; Xing S; Feng F; Liu W; Guo Q; Zhao L; Yang P; Sun H
    J Med Chem; 2023 Jul; 66(14):9537-9560. PubMed ID: 37409679
    [TBL] [Abstract][Full Text] [Related]  

  • 49. Intracrine Androgens and AKR1C3 Activation Confer Resistance to Enzalutamide in Prostate Cancer.
    Liu C; Lou W; Zhu Y; Yang JC; Nadiminty N; Gaikwad NW; Evans CP; Gao AC
    Cancer Res; 2015 Apr; 75(7):1413-22. PubMed ID: 25649766
    [TBL] [Abstract][Full Text] [Related]  

  • 50. Buparlisib is a novel inhibitor of daunorubicin reduction mediated by aldo-keto reductase 1C3.
    Bukum N; Novotna E; Morell A; Hofman J; Wsol V
    Chem Biol Interact; 2019 Apr; 302():101-107. PubMed ID: 30703376
    [TBL] [Abstract][Full Text] [Related]  

  • 51. In vitro and in vivo characterisation of ASP9521: a novel, selective, orally bioavailable inhibitor of 17β-hydroxysteroid dehydrogenase type 5 (17βHSD5; AKR1C3).
    Kikuchi A; Furutani T; Azami H; Watanabe K; Niimi T; Kamiyama Y; Kuromitsu S; Baskin-Bey E; Heeringa M; Ouatas T; Enjo K
    Invest New Drugs; 2014 Oct; 32(5):860-70. PubMed ID: 24981575
    [TBL] [Abstract][Full Text] [Related]  

  • 52. Development of highly potent and specific AKR1C3 inhibitors to restore the chemosensitivity of drug-resistant breast cancer.
    Liu Y; Chen Y; Jiang J; Chu X; Guo Q; Zhao L; Feng F; Liu W; Zhang X; He S; Yang P; Fang P; Sun H
    Eur J Med Chem; 2023 Feb; 247():115013. PubMed ID: 36566714
    [TBL] [Abstract][Full Text] [Related]  

  • 53. Selective inhibition of aldo-keto reductase 1C3: a novel mechanism involved in midostaurin and daunorubicin synergism.
    Morell A; Novotná E; Milan J; Danielisová P; Büküm N; Wsól V
    Arch Toxicol; 2021 Jan; 95(1):67-78. PubMed ID: 33025066
    [TBL] [Abstract][Full Text] [Related]  

  • 54. Development of potent and selective indomethacin analogues for the inhibition of AKR1C3 (Type 5 17β-hydroxysteroid dehydrogenase/prostaglandin F synthase) in castrate-resistant prostate cancer.
    Liedtke AJ; Adeniji AO; Chen M; Byrns MC; Jin Y; Christianson DW; Marnett LJ; Penning TM
    J Med Chem; 2013 Mar; 56(6):2429-46. PubMed ID: 23432095
    [TBL] [Abstract][Full Text] [Related]  

  • 55. Morpholylureas are a new class of potent and selective inhibitors of the type 5 17-β-hydroxysteroid dehydrogenase (AKR1C3).
    Flanagan JU; Atwell GJ; Heinrich DM; Brooke DG; Silva S; Rigoreau LJ; Trivier E; Turnbull AP; Raynham T; Jamieson SM; Denny WA
    Bioorg Med Chem; 2014 Feb; 22(3):967-77. PubMed ID: 24411201
    [TBL] [Abstract][Full Text] [Related]  

  • 56. Characterization of a highly specific monoclonal antibody against human aldo-keto reductase AKR1C3.
    Liu J; He P; Lin L; Zhao Y; Deng W; Ding H; Li Q; Wang Z
    Steroids; 2019 Mar; 143():73-79. PubMed ID: 30639543
    [TBL] [Abstract][Full Text] [Related]  

  • 57. Overexpression of AKR1C3 significantly enhances human prostate cancer cells resistance to radiation.
    Sun SQ; Gu X; Gao XS; Li Y; Yu H; Xiong W; Yu H; Wang W; Li Y; Teng Y; Zhou D
    Oncotarget; 2016 Jul; 7(30):48050-48058. PubMed ID: 27385003
    [TBL] [Abstract][Full Text] [Related]  

  • 58. Structure of AKR1C3 with 3-phenoxybenzoic acid bound.
    Jackson VJ; Yosaatmadja Y; Flanagan JU; Squire CJ
    Acta Crystallogr Sect F Struct Biol Cryst Commun; 2012 Apr; 68(Pt 4):409-13. PubMed ID: 22505408
    [TBL] [Abstract][Full Text] [Related]  

  • 59. Interaction between leukocyte aldo-keto reductase 1C3 activity, genotypes, biological, lifestyle and clinical features in a prostate cancer cohort from New Zealand.
    Karunasinghe N; Symes E; Gamage A; Wang A; Murray P; Zhu S; Goudie M; Masters J; Ferguson LR
    PLoS One; 2019; 14(5):e0217373. PubMed ID: 31125365
    [TBL] [Abstract][Full Text] [Related]  

  • 60. Human dehydrogenase/reductase SDR family member 11 (DHRS11) and aldo-keto reductase 1C isoforms in comparison: Substrate and reaction specificity in the reduction of 11-keto-C
    Endo S; Morikawa Y; Kudo Y; Suenami K; Matsunaga T; Ikari A; Hara A
    J Steroid Biochem Mol Biol; 2020 May; 199():105586. PubMed ID: 31926269
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 14.