697 related articles for article (PubMed ID: 29606353)
1. Direct Promoter Repression by BCL11A Controls the Fetal to Adult Hemoglobin Switch.
Liu N; Hargreaves VV; Zhu Q; Kurland JV; Hong J; Kim W; Sher F; Macias-Trevino C; Rogers JM; Kurita R; Nakamura Y; Yuan GC; Bauer DE; Xu J; Bulyk ML; Orkin SH
Cell; 2018 Apr; 173(2):430-442.e17. PubMed ID: 29606353
[TBL] [Abstract][Full Text] [Related]
2. Transcription factor competition at the γ-globin promoters controls hemoglobin switching.
Liu N; Xu S; Yao Q; Zhu Q; Kai Y; Hsu JY; Sakon P; Pinello L; Yuan GC; Bauer DE; Orkin SH
Nat Genet; 2021 Apr; 53(4):511-520. PubMed ID: 33649594
[TBL] [Abstract][Full Text] [Related]
3. Human fetal hemoglobin expression is regulated by the developmental stage-specific repressor BCL11A.
Sankaran VG; Menne TF; Xu J; Akie TE; Lettre G; Van Handel B; Mikkola HK; Hirschhorn JN; Cantor AB; Orkin SH
Science; 2008 Dec; 322(5909):1839-42. PubMed ID: 19056937
[TBL] [Abstract][Full Text] [Related]
4. Featured Article: Modulation of fetal hemoglobin in hereditary persistence of fetal hemoglobin deletion type-2, compared to Sicilian δβ-thalassemia, by BCL11A and SOX6-targeting microRNAs.
Fornari TA; Lanaro C; Albuquerque DM; Ferreira R; Costa FF
Exp Biol Med (Maywood); 2017 Feb; 242(3):267-274. PubMed ID: 27591578
[TBL] [Abstract][Full Text] [Related]
5. Induction of adult levels of β-globin in human erythroid cells that intrinsically express embryonic or fetal globin by transduction with KLF1 and BCL11A-XL.
Trakarnsanga K; Wilson MC; Lau W; Singleton BK; Parsons SF; Sakuntanaga P; Kurita R; Nakamura Y; Anstee DJ; Frayne J
Haematologica; 2014 Nov; 99(11):1677-85. PubMed ID: 25107887
[TBL] [Abstract][Full Text] [Related]
6. Identification of novel HPFH-like mutations by CRISPR base editing that elevate the expression of fetal hemoglobin.
Ravi NS; Wienert B; Wyman SK; Bell HW; George A; Mahalingam G; Vu JT; Prasad K; Bandlamudi BP; Devaraju N; Rajendiran V; Syedbasha N; Pai AA; Nakamura Y; Kurita R; Narayanasamy M; Balasubramanian P; Thangavel S; Marepally S; Velayudhan SR; Srivastava A; DeWitt MA; Crossley M; Corn JE; Mohankumar KM
Elife; 2022 Feb; 11():. PubMed ID: 35147495
[TBL] [Abstract][Full Text] [Related]
7. MicroRNA-486-3p regulates γ-globin expression in human erythroid cells by directly modulating BCL11A.
Lulli V; Romania P; Morsilli O; Cianciulli P; Gabbianelli M; Testa U; Giuliani A; Marziali G
PLoS One; 2013; 8(4):e60436. PubMed ID: 23593217
[TBL] [Abstract][Full Text] [Related]
8. Natural regulatory mutations elevate the fetal globin gene via disruption of BCL11A or ZBTB7A binding.
Martyn GE; Wienert B; Yang L; Shah M; Norton LJ; Burdach J; Kurita R; Nakamura Y; Pearson RCM; Funnell APW; Quinlan KGR; Crossley M
Nat Genet; 2018 Apr; 50(4):498-503. PubMed ID: 29610478
[TBL] [Abstract][Full Text] [Related]
9. Highly efficient therapeutic gene editing of human hematopoietic stem cells.
Wu Y; Zeng J; Roscoe BP; Liu P; Yao Q; Lazzarotto CR; Clement K; Cole MA; Luk K; Baricordi C; Shen AH; Ren C; Esrick EB; Manis JP; Dorfman DM; Williams DA; Biffi A; Brugnara C; Biasco L; Brendel C; Pinello L; Tsai SQ; Wolfe SA; Bauer DE
Nat Med; 2019 May; 25(5):776-783. PubMed ID: 30911135
[TBL] [Abstract][Full Text] [Related]
10. Targeted deletion of BCL11A gene by CRISPR-Cas9 system for fetal hemoglobin reactivation: A promising approach for gene therapy of beta thalassemia disease.
Khosravi MA; Abbasalipour M; Concordet JP; Berg JV; Zeinali S; Arashkia A; Azadmanesh K; Buch T; Karimipoor M
Eur J Pharmacol; 2019 Jul; 854():398-405. PubMed ID: 31039344
[TBL] [Abstract][Full Text] [Related]
11. Epigenetic inactivation of ERF reactivates γ-globin expression in β-thalassemia.
Bao X; Zhang X; Wang L; Wang Z; Huang J; Zhang Q; Ye Y; Liu Y; Chen D; Zuo Y; Liu Q; Xu P; Huang B; Fang J; Lao J; Feng X; Li Y; Kurita R; Nakamura Y; Yu W; Ju C; Huang C; Mohandas N; Li D; Zhao C; Xu X
Am J Hum Genet; 2021 Apr; 108(4):709-721. PubMed ID: 33735615
[TBL] [Abstract][Full Text] [Related]
12. Hemoglobin switching's surprise: the versatile transcription factor BCL11A is a master repressor of fetal hemoglobin.
Bauer DE; Orkin SH
Curr Opin Genet Dev; 2015 Aug; 33():62-70. PubMed ID: 26375765
[TBL] [Abstract][Full Text] [Related]
13. Hemoglobin genetics: recent contributions of GWAS and gene editing.
Smith EC; Orkin SH
Hum Mol Genet; 2016 Oct; 25(R2):R99-R105. PubMed ID: 27340226
[TBL] [Abstract][Full Text] [Related]
14. Base editing of key residues in the BCL11A-XL-specific zinc finger domains derepresses fetal globin expression.
Rajendiran V; Devaraju N; Haddad M; Ravi NS; Panigrahi L; Paul J; Gopalakrishnan C; Wyman S; Ariudainambi K; Mahalingam G; Periyasami Y; Prasad K; George A; Sukumaran D; Gopinathan S; Pai AA; Nakamura Y; Balasubramanian P; Ramalingam R; Thangavel S; Velayudhan SR; Corn JE; Mackay JP; Marepally S; Srivastava A; Crossley M; Mohankumar KM
Mol Ther; 2024 Mar; 32(3):663-677. PubMed ID: 38273654
[TBL] [Abstract][Full Text] [Related]
15. A genome-editing strategy to treat β-hemoglobinopathies that recapitulates a mutation associated with a benign genetic condition.
Traxler EA; Yao Y; Wang YD; Woodard KJ; Kurita R; Nakamura Y; Hughes JR; Hardison RC; Blobel GA; Li C; Weiss MJ
Nat Med; 2016 Sep; 22(9):987-90. PubMed ID: 27525524
[TBL] [Abstract][Full Text] [Related]
16. Human globin knock-in mice complete fetal-to-adult hemoglobin switching in postnatal development.
McConnell SC; Huo Y; Liu S; Ryan TM
Mol Cell Biol; 2011 Feb; 31(4):876-83. PubMed ID: 21173165
[TBL] [Abstract][Full Text] [Related]
17. Transcriptional silencing of fetal hemoglobin by BCL11A.
Sankaran VG; Xu J; Orkin SH
Ann N Y Acad Sci; 2010 Aug; 1202():64-8. PubMed ID: 20712774
[TBL] [Abstract][Full Text] [Related]
18. Transcriptional regulators Myb and BCL11A interplay with DNA methyltransferase 1 in developmental silencing of embryonic and fetal β-like globin genes.
Roosjen M; McColl B; Kao B; Gearing LJ; Blewitt ME; Vadolas J
FASEB J; 2014 Apr; 28(4):1610-20. PubMed ID: 24371119
[TBL] [Abstract][Full Text] [Related]
19. Transcription factors LRF and BCL11A independently repress expression of fetal hemoglobin.
Masuda T; Wang X; Maeda M; Canver MC; Sher F; Funnell AP; Fisher C; Suciu M; Martyn GE; Norton LJ; Zhu C; Kurita R; Nakamura Y; Xu J; Higgs DR; Crossley M; Bauer DE; Orkin SH; Kharchenko PV; Maeda T
Science; 2016 Jan; 351(6270):285-9. PubMed ID: 26816381
[TBL] [Abstract][Full Text] [Related]
20. Transcriptional silencing of {gamma}-globin by BCL11A involves long-range interactions and cooperation with SOX6.
Xu J; Sankaran VG; Ni M; Menne TF; Puram RV; Kim W; Orkin SH
Genes Dev; 2010 Apr; 24(8):783-98. PubMed ID: 20395365
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
